User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Efficient syntheses of the polyene fragments present in amphidinols

Primary tabs

Cossy, Janine Tsuchiya, Tomoki Ferrie, Laurent Reymond, Sebastien Kreuzer, Thomas Jourdain, Pierre [UCL] Marko, Istvan [UCL]

The C53-C67 and C53-C65 polyene fragments of amphidinols have been synthesized in an efficient and convergent fashion from sorbic acid in good overall yields (30-31%) by employing a chemoselective cross-metathesis of a Weinreb amide and a Julia-Kocienski olefination as the key steps.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 2007
Language Anglais
Journal information "Synlett : accounts and rapid communications in synthetic organic chemistry" - , no. 14, p. 2286-2288 (2007)
Peer reviewed yes
Publisher Georg Thieme Verlag Kg (Stuttgart)
issn 0936-5214
e-issn 1437-2096
Publication status Publié
Affiliation UCL - SC/CHIM - Département de chimie
Keywords cross-metathesis ; Julia-Kocienski olefination ; amphidinols ; polyenes
Links
Bibliographic reference Cossy, Janine ; Tsuchiya, Tomoki ; Ferrie, Laurent ; Reymond, Sebastien ; Kreuzer, Thomas ; et. al. Efficient syntheses of the polyene fragments present in amphidinols. In: Synlett : accounts and rapid communications in synthetic organic chemistry, , no. 14, p. 2286-2288 (2007)
Permanent URL http://hdl.handle.net/2078.1/37321