User menu

Chronic relapsing experimental allergic encephalomyelitis (CREAE) in plasminogen activator inhibitor-1 knockout mice: the effect of fibrinolysis during neuroinflammation

Bibliographic reference East, E. ; Gveric, D. ; Baker, D. ; Pryce, G. ; Lijnen, H. R. ; et. al. Chronic relapsing experimental allergic encephalomyelitis (CREAE) in plasminogen activator inhibitor-1 knockout mice: the effect of fibrinolysis during neuroinflammation. In: Neuropathology and Applied Neurobiology, Vol. 34, no. 2, p. 216-230 (2008)
Permanent URL
  1. East Emma, Baker David, Pryce Gareth, Lijnen H. Roger, Cuzner M. Louise, Gverić Djordje, A Role for the Plasminogen Activator System in Inflammation and Neurodegeneration in the Central Nervous System during Experimental Allergic Encephalomyelitis, 10.1016/s0002-9440(10)62996-3
  2. Gveric D., Plasminogen activators in multiple sclerosis lesions: Implications for the inflammatory response and axonal damage, 10.1093/brain/124.10.1978
  3. Lo Eng H., Wang Xiaoying, Cuzner M. Louise, Extracellular proteolysis in brain injury and inflammation: Role for plasminogen activators and matrix metalloproteinases, 10.1002/jnr.10270
  4. Teesalu Tambet, Hinkkanen Ari E., Vaheri Antti, Coordinated Induction of Extracellular Proteolysis Systems During Experimental Autoimmune Encephalomyelitis in Mice, 10.1016/s0002-9440(10)63073-8
  5. Gveric D., Impaired fibrinolysis in multiple sclerosis: a role for tissue plasminogen activator inhibitors, 10.1093/brain/awg167
  6. Akenami F O, Koskiniemi M, Farkkila M, Vaheri A, Cerebrospinal fluid plasminogen activator inhibitor-1 in patients with neurological disease., 10.1136/jcp.50.2.157
  7. Akassoglou Katerina, Kombrinck Keith W., Degen Jay L., Strickland Sidney, Tissue Plasminogen Activator–Mediated Fibrinolysis Protects against Axonal Degeneration and Demyelination after Sciatic Nerve Injury, 10.1083/jcb.149.5.1157
  8. Paterson PY, Fed Proc, 35, 2428 (1976)
  9. Koh Chang-Sung, Gausas John, Paterson Philip Y., Neurovascular permeability and fibrin deposition in the central neuraxis of Lewis rats with cell-transferred experimental allergic encephalomyelitis in relationship to clinical and histopathological features of the disease, 10.1016/0165-5728(93)90024-s
  10. Binder BR, News Physiol Sci, 17, 56 (2002)
  11. Carmeliet P, Ann N Y Acad Sci, 17, 367 (1995)
  12. Carmeliet P, J Clin Invest, 92, 2746 (1993)
  13. Baker D., O'Neill J.K., Gschmeissner S.E., Wilcox C.E., Butter C., Turk J.L., Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice, 10.1016/0165-5728(90)90019-j
  14. Levine S, J Immunol, 110, 139 (1973)
  15. Allen Sandra J., Baker David, O'Neill Janet K., Davison Alan N., Turk John L., Isolation and Characterization of Cells Infiltrating the Spinal Cord during the Course of Chronic Relapsing Experimental Allergic Encephalomyelitis in the Biozzi AB/H Mouse, 10.1006/cimm.1993.1031
  16. Gveric, Cuzner, Newcombe, Insulin-like growth factors and binding proteins in multiple sclerosis plaques, 10.1046/j.1365-2990.1999.00187.x
  17. Lowry OH, J Biol Chem, 193, 265 (1951)
  18. Declerck PJ, Thromb Haemost, 74, 1305 (1995)
  19. Urano T, Haemostasis, 26, 220 (1996)
  20. Pryce Gareth, Ahmed Zubair, Hankey Deborah J. R., Jackson Samuel J., Croxford J. Ludovic, Pocock Jennifer M., Ledent Catherine, Petzold Axel, Thompson Alan J., Giovannoni Gavin, Cuzner M. Louise, Baker David, Cannabinoids inhibit neurodegeneration in models of multiple sclerosis, 10.1093/brain/awg224
  21. Butter C., Baker D., O'Neill J.K., Turk J.L., Mononuclear cell trafficking and plasma protein extravasation into the CNS during chronic relapsing experimental allergic encephalomyelitis in Biozzi AB/H mice, 10.1016/0022-510x(91)90209-p
  22. Johnson G. V. W., Jope R. S., The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration, 10.1002/jnr.490330402
  23. Matesic DF, J Neurochem, 63, 1012 (1994)
  24. Zhu Bing, Luo Liqing, Moore G. R. Wayne, Paty Donald W., Cynader Max S., Dendritic and Synaptic Pathology in Experimental Autoimmune Encephalomyelitis, 10.1016/s0002-9440(10)64298-8
  25. Kerschensteiner Martin, Bareyre Florence M., Buddeberg Bigna S., Merkler Doron, Stadelmann Christine, Brück Wolfgang, Misgeld Thomas, Schwab Martin E., Remodeling of Axonal Connections Contributes to Recovery in an Animal Model of Multiple Sclerosis, 10.1084/jem.20040452
  26. Wegner C., Esiri M. M., Chance S. A., Palace J., Matthews P. M., Neocortical neuronal, synaptic, and glial loss in multiple sclerosis, 10.1212/01.wnl.0000237551.26858.39
  27. Claudio Luz, Raine Cedric S., Brosnan Celia F., Evidence of persistent blood-brain barrier abnormalities in chronic-progressive multiple sclerosis, 10.1007/bf00296505
  28. Dellas C, Thromb Haemost, 93, 631 (2005)
  29. Loskutoff DJ, APMIS, 107, 54 (1999)
  30. Hertig Alexandre, Rondeau Eric, Plasminogen activator inhibitor type 1: the two faces of the same coin : , 10.1097/00041552-200401000-00006
  31. Deng G., Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?, 10.1083/jcb.134.6.1563
  32. Benowitz Larry I, Routtenberg Aryeh, GAP-43: an intrinsic determinant of neuronal development and plasticity, 10.1016/s0166-2236(96)10072-2
  33. Wegner C., Esiri M. M., Chance S. A., Palace J., Matthews P. M., Neocortical neuronal, synaptic, and glial loss in multiple sclerosis, 10.1212/01.wnl.0000237551.26858.39
  34. Bogdanovic N., Davidsson P., Volkmann I., Winblad B., Blennow K., Growth-associated protein GAP-43 in the frontal cortex and in the hippocampus in Alzheimer's disease: an immunohistochemical and quantitative study, 10.1007/s007020070088
  35. Thompson Stephanie N., Gibson Tonya R., Thompson Brian M., Deng Ying, Hall Edward D., Relationship of calpain-mediated proteolysis to the expression of axonal and synaptic plasticity markers following traumatic brain injury in mice, 10.1016/j.expneurol.2006.04.013
  36. Akassoglou Katerina, Yu Wei-Ming, Akpinar Pinar, Strickland Sidney, Fibrin Inhibits Peripheral Nerve Remyelination by Regulating Schwann Cell Differentiation, 10.1016/s0896-6273(02)00617-7
  37. Schachtrup C., Lu P., Jones L. L., Lee J. K., Lu J., Sachs B. D., Zheng B., Akassoglou K., Fibrinogen inhibits neurite outgrowth via beta3 integrin-mediated phosphorylation of the EGF receptor, 10.1073/pnas.0704045104
  38. Huber Kurt, 10.1023/a:1011955018052
  40. Smiley S. T., King J. A., Hancock W. W., Fibrinogen Stimulates Macrophage Chemokine Secretion Through Toll-Like Receptor 4, 10.4049/jimmunol.167.5.2887
  41. Flick Matthew J., Du XinLi, Witte David P., Jiroušková Markéta, Soloviev Dmitry A., Busuttil Steven J., Plow Edward F., Degen Jay L., Leukocyte engagement of fibrin(ogen) via the integrin receptor αMβ2/Mac-1 is critical for host inflammatory response in vivo, 10.1172/jci200420741
  42. Adams RA, Mol Interv, 4, 163 (2004)
  43. Cruz-Topete D, Iwaki T, Ploplis VA, Castellino FJ, Delayed inflammatory responses to endotoxin in fibrinogen-deficient mice, 10.1002/path.2060
  44. Languino L. R., Duperray A., Joganic K. J., Fornaro M., Thornton G. B., Altieri D. C., Regulation of leukocyte-endothelium interaction and leukocyte transendothelial migration by intercellular adhesion molecule 1-fibrinogen recognition., 10.1073/pnas.92.5.1505
  45. Akassoglou K., Adams R. A., Bauer J., Mercado P., Tseveleki V., Lassmann H., Probert L., Strickland S., Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis, 10.1073/pnas.0303859101
  46. Adams Ryan A., Bauer Jan, Flick Matthew J., Sikorski Shoana L., Nuriel Tal, Lassmann Hans, Degen Jay L., Akassoglou Katerina, The fibrin-derived γ377-395peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease, 10.1084/jem.20061931
  47. Strickland D. K., Ranganathan S., Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling, 10.1046/j.1538-7836.2003.00330.x
  48. Rogove AD, J Cell Sci, 112, 4007 (1999)
  49. Dobrovolsky A. B., Titaeva E. V., 10.1023/a:1013960416302
  50. Hastings Gregg A., Coleman Timothy A., Haudenschild Christian C., Stefansson Steingrimur, Smith Elizabeth P., Barthlow Ray, Cherry Scott, Sandkvist Maria, Lawrence Daniel A., Neuroserpin, a Brain-associated Inhibitor of Tissue Plasminogen Activator Is Localized Primarily in Neurons : IMPLICATIONS FOR THE REGULATION OF MOTOR LEARNING AND NEURONAL SURVIVAL, 10.1074/jbc.272.52.33062
  51. Teesalu T, Thromb Haemost, 92, 358 (2004)
  52. LEIK C. E., SU E. J., NAMBI P., CRANDALL D. L., LAWRENCE D. A., Effect of pharmacologic plasminogen activator inhibitor-1 inhibition on cell motility and tumor angiogenesis, 10.1111/j.1538-7836.2006.02244.x
  53. Gorlatova Natalia V., Cale Jacqueline M., Elokdah Hassan, Li Donghua, Fan Kristi, Warnock Mark, Crandall David L., Lawrence Daniel A., Mechanism of Inactivation of Plasminogen Activator Inhibitor-1 by a Small Molecule Inhibitor, 10.1074/jbc.m611642200