Palma, Margarida
Seret, Marie-Line
[UCL]
Baret, Philippe
[UCL]
The sugar porter family in yeasts encompasses a wide variety of transporters including the hexose transporters and glucose sensors. We analysed a total of 75 members from both groups in nine hemiascomycetous species, with complete and well-annotated genomes: Saccharomyces cerevisiae, Candida glabrata, Zygosaccharomyces rouxii, Kluyveromyces thermotolerans, Saccharomyces kluyverii, Kluyveromyces lactis, Eremothecium gossypii, Debaryomyces hansenii and Yarrowia lipolytica. We present a model for the evolution of the hexose transporters and glucose sensors, supported by two types of complementary evidences: phylogeny and neighbourhood analysis. Five lineages of evolution were identified and discussed according to different mechanisms of gene evolution: lineage A for HXT1, HXT3, HXT4, HXT5, HXT6 and HXT7; lineage B for HXT2 and HXT10; lineage C for HXT8; lineage D for HXT14; and lineage E for SNF3 and RGT2.
Bibliographic reference |
Palma, Margarida ; Seret, Marie-Line ; Baret, Philippe. Combined phylogenetic and neighbourhood analysis of the hexose transporters and glucose sensors in yeasts. In: FEMS Yeast Research, Vol. 9, no. 4, p. 526-534 (2009) |
Permanent URL |
http://hdl.handle.net/2078.1/35596 |