User menu

A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3.

Bibliographic reference Coulie, Pierre ; Karanikas, V ; Colau, Didier ; Lurquin, C. ; Landry, C ; et. al. A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3.. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, no. 18, p. 10290-5 (2001)
Permanent URL
  1. van der Bruggen P, Traversari C, Chomez P, Lurquin C, De Plaen E, Van den Eynde B, Knuth A, Boon T, A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma, 10.1126/science.1840703
  2. Van den Eynde Benoît J, van der Bruggen Pierre, T cell defined tumor antigens, 10.1016/s0952-7915(97)80050-7
  3. Gaugler B., Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes, 10.1084/jem.179.3.921
  4. De Smet C., De Backer O., Faraoni I., Lurquin C., Brasseur F., Boon T., The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation., 10.1073/pnas.93.14.7149
  5. De Smet Charles, Lurquin Christophe, Lethé Bernard, Martelange Valérie, Boon Thierry, DNA Methylation Is the Primary Silencing Mechanism for a Set of Germ Line- and Tumor-Specific Genes with a CpG-Rich Promoter, 10.1128/mcb.19.11.7327
  6. Brasseur Francis, Rimoldi Donata, Liénard Danielle, Lethé Bernard, Carrel Stefan, Arienti Flavio, Suter Ludwig, Vanwijck Romain, Bourlond André, Humblet Yves, Vacca Angelo, Conese Marina, Lahaye Thierry, Degiovanni Gérard, Deraemaecker Rika, Beauduin Marc, Sastre Xavier, Salamon Emile, Dréno Brigitte, Jäger Elke, Knuth Alex, Chevreau Christine, Suciu Stefan, Lachapelle Jean-Marie, Pouillart Pierre, Parmiani Giorgio, Lejeune Ferdy, Cerottini Jean-Charles, Boon Thierry, Marchand Marie, Expression ofMAGE genes in primary and metastatic cutaneous melanoma, 10.1002/ijc.2910630313
  7. Marchand M., Weynants P., Rankin E., Arienti F., Belli F., Parmiani G., Cascinelli N., Bourlond A., Vanwuck R., Humblet Y., Canon J.-L., Laurent C., Naeyaert J.-M., Plagne R., Deraemaeker R., Knuth A., Jager E., Brasseur F., Herman J., Couiae P. G., Boon T., Tumor regression responses in melanoma patients treated with a peptide encoded by geneMAGES-3, 10.1002/ijc.2910630622
  8. Marchand Marie, van Baren Nicolas, Weynants Patrick, Brichard Vincent, Dr�no Brigitte, Tessier Marie-H�l�ne, Rankin Elaine, Parmiani Giorgio, Arienti Flavio, Humblet Yves, Bourlond Andr�, Vanwijck Romain, Li�nard Danielle, Beauduin Marc, Dietrich Pierre-Yves, Russo Vincenzo, Kerger Joseph, Masucci Giuseppe, J�ger Elke, De Greve Jacques, Atzpodien Jens, Brasseur Francis, Coulie Pierre G., van der Bruggen Pierre, Boon Thierry, Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by geneMAGE-3 and presented by HLA-A1, 10.1002/(sici)1097-0215(19990118)80:2<219::aid-ijc10>;2-s
  9. Nestle Frank O., Alijagic Selma, Gilliet Michel, Sun Yuansheng, Grabbe Stephan, Dummer Reinhard, Burg Günter, Schadendorf Dirk, Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells, 10.1038/nm0398-328
  10. Thurner Beatrice, Haendle Ina, Röder Claudia, Dieckmann Detlef, Keikavoussi Petra, Jonuleit Helmut, Bender Armin, Maczek Christian, Schreiner Doris, von den Driesch Peter, Bröcker Eva B., Steinman Ralph M., Enk Alexander, Kämpgen Eckhart, Schuler Gerold, Vaccination with Mage-3a1 Peptide–Pulsed Mature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells and Induces Regression of Some Metastases in Advanced Stage IV Melanoma, 10.1084/jem.190.11.1669
  11. Baldo Maurizio, Schiavon Mauro, Cicogna Pier A., Boccato Paolo, Mazzoleni Francesco, Spontaneous Regression of Subcutaneous Metastasis of Cutaneous Melanoma : , 10.1097/00006534-199212000-00022
  12. Toes R. E., Offringa R., Blom R. J., Melief C. J., Kast W. M., Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction., 10.1073/pnas.93.15.7855
  13. Schild Hansjörg, Deres Karl, Wiesmüller Karl-Heinz, Jung Günther, Rammensee Hans-Georg, Efficiency of peptides and lipopeptides forin vivo priming of virus-specific cytotoxic T cells, 10.1002/eji.1830211102
  14. Chaux Pascal, Vantomme Valérie, Coulie Pierre, Boon Thierry, van der Bruggen Pierre, Estimation of the frequencies of anti-MAGE-3 cytolytic T-lymphocyte precursors in blood from individuals without cancer, 10.1002/(sici)1097-0215(19980812)77:4<538::aid-ijc11>;2-2
  15. Altman J. D., Moss P. A. H., Goulder P. J. R., Barouch D. H., McHeyzer-Williams M. G., Bell J. I., McMichael A. J., Davis M. M., Phenotypic Analysis of Antigen-Specific T Lymphocytes, 10.1126/science.274.5284.94
  16. Baurain J.-F., Colau D., van Baren N., Landry C., Martelange V., Vikkula M., Boon T., Coulie P. G., High Frequency of Autologous Anti-Melanoma CTL Directed Against an Antigen Generated by a Point Mutation in a New Helicase Gene, 10.4049/jimmunol.164.11.6057
  17. Genevée Catherine, Diu Anita, Nierat Janine, Caignard Anne, Dietrich Pierre-Yves, Ferradini Laurent, Roman-Roman Sergio, Triebel Frédéaric, Hercend Thierry, An experimentally validated panel of subfamily-specific oligonucleotide primers (Vα1-w29/Vβ1-w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction, 10.1002/eji.1830220522
  18. Immunology, 162, 7080 (1999)
  19. Hamann D., Baars P. A., Rep M. H.G., Hooibrink B., Kerkhof-Garde S. R., Klein M. R., Lier R. A.W. v., Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells, 10.1084/jem.186.9.1407
  20. Sallusto Federica, Lenig Danielle, Förster Reinhold, Lipp Martin, Lanzavecchia Antonio, Two subsets of memory T lymphocytes with distinct homing potentials and effector functions, 10.1038/44385
  21. Maryanski Janet L., Van Snick Jacques, Cerottini Jean-Charles, Boon Thierry, Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. III. Clonal analysis of the syngeneic cytolytic T lymphocyte response, 10.1002/eji.1830120508
  22. Karanikas, Cancer Research, 61, 3718 (2001)
  23. Callan Margaret F.C., Steven Neil, Krausa Pete, Wilson Jamie D.K., Moss Paul A.H., Gillespie Geraldine M., Bell John I., Rickinson Alan B., McMichael Andrew J., Large clonal expansions of CD8+ T cells in acute infectious mononucleosis, 10.1038/nm0896-906
  24. Weekes, The Journal of Immunology, 162, 7569 (1999)
  25. Weekes, Journal of Virology, 73, 2099 (1999)
  26. Wilson Jamie D.K., Ogg Graham S., Allen Rachel L., Goulder Philip J.R., Kelleher Anthony, Sewell Andy K., O'Callaghan Christopher A., Rowland-Jones Sarah L., Callan Margaret F.C., McMichael Andrew J., Oligoclonal Expansions of CD8+T Cells in Chronic HIV Infection Are Antigen Specific, 10.1084/jem.188.4.785
  27. Valmori D., Dutoit V., Lienard D., Lejeune F., Speiser D., Rimoldi D., Cerundolo V., Dietrich P.-Y., Cerottini J.-C., Romero P., Tetramer-Guided Analysis of TCR  -Chain Usage Reveals a Large Repertoire of Melan-A-Specific CD8+ T Cells in Melanoma Patients, 10.4049/jimmunol.165.1.533
  28. Davis Mark M., Lee Peter P., Yee Cassian, Savage Peter A., Fong Lawrence, Brockstedt Dirk, Weber Jeffrey S., Johnson Denise, Swetter Susan, Thompson John, Greenberg Philip D., Roederer Mario, 10.1038/9525
  29. Pittet Mikaël J., Valmori Danila, Dunbar P. Rod, Speiser Daniel E., Liénard Danielle, Lejeune Ferdy, Fleischhauer Katharina, Cerundolo Vincenzo, Cerottini Jean-Charles, Romero Pedro, High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals, 10.1084/jem.190.5.705