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Study claiming target in sepsis with erythromycin has no effect upon mortality and secondary outcomes includes patients with CRRT and RRT.

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Honoré, Patrick [UCL] Blackman, Sydney Perriens, Emily Bousbiat, Ibrahim

(eng) Reijnders et al. recently published an article concluding that, in their target trial emulation on critically ill patients with sepsis, they could not demonstrate an effect of treatment with low-dose erythromycin on mortality, secondary clinical outcomes, or host response biomarkers. However, when carefully reviewing the baseline characteristics, we found that 49.8% of the patients in the treated group had acute kidney injury (AKI). [...]

Document type Article de périodique (Journal article) – Lettre à l'éditeur
Access type Accès libre
Publication date 2023
Language Anglais
Journal information "Critical care" - Vol. 27, no. 1, p. 52 [1-2] (2023)
Peer reviewed yes
Publisher BioMed Central Ltd ((United Kingdom) London)
issn 1364-8535
e-issn 1466-609X
Publication status Publié
Affiliations UCL - SSS/IREC/MONT - Pôle Mont Godinne
UCL - (MGD) Services des soins intensifs
MESH Subject Humans ; Critical Illness ; Erythromycin ; Renal Replacement Therapy ; Acute Kidney Injury ; Sepsis
Links
Bibliographic reference Honoré, Patrick ; Blackman, Sydney ; Perriens, Emily ; Bousbiat, Ibrahim. Study claiming target in sepsis with erythromycin has no effect upon mortality and secondary outcomes includes patients with CRRT and RRT.. In: Critical care, Vol. 27, no. 1, p. 52 [1-2] (2023)
Permanent URL http://hdl.handle.net/2078.1/272578