Coulie, Pierre G.
[UCL]
van der Bruggen, Pierre
[UCL]
Following vaccination with defined tumor antigens that are recognized by T cells, a small proportion of cancer patients display tumor regressions. Several reports describe anti-vaccine T-cell responses, evaluated with a variety of methods, for example, by assessing T-cell function or expression of specific TCR. However, a correlation between these T-cell responses and the tumor regressions has not yet been established. It appears that some patients display tumor regression with an unexpectedly low frequency of anti-vaccine T cells.
Bibliographic reference |
Coulie, Pierre G. ; van der Bruggen, Pierre. T-cell responses of vaccinated cancer patients.. In: Current Opinion in Immunology, Vol. 15, no. 2, p. 131-137 (2003) |
Permanent URL |
http://hdl.handle.net/2078.1/26749 |