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Comprehensive assessment of the severity and mechanism of aortic regurgitation using multidetector CT and MR.

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Goffinet, Céline [UCL] Kersten, Valérie [UCL] Pouleur, Anne-Catherine [UCL] Le Polain De Waroux, Jean-Benoît [UCL] Vancraeynest, David [UCL] Pasquet, Agnes [UCL] Vanoverschelde, Jean-Louis [UCL] Gerber, Bernhard [UCL]

Recent studies have suggested that both cardiac magnetic resonance (MR) and multidetector computed tomography (MDCT) can quantify aortic regurgitation (AR) by planimetry of the anatomical regurgitant orifice (ARO). However, this measurement was not compared with quantitative assessment of AR such as the effective regurgitant orifice (ERO) by proximal isosurface area (PISA) transthoracic echocardiography (TTE) or phase contrast MR. In 42 patients (34 men, age 54 +/- 11 years) we compared planimetered ARO by MDCT and MR with ERO and regurgitant volume by PISA TTE and phase contrast MR. ARO by MDCT (r = 0.87, p < 0.001) and MR (r = 0.81, p < 0.001) correlated highly with ERO by TTE. However, ARO by MDCT (27 +/- 15 mm(2), p < 0.001), but not by MR (23 +/- 13 mm(2), p = 0.58), were larger than PISA ERO (22 +/- 11 mm(2)). ARO by MDCT (r = 0.78, p < 0.001; r = 0.85, p < 0.001) and MR (r = 0.85, p < 0.001; r = 0.87 p < 0.001) correlated well with regurgitant volume by PISA and phase contrast MR. Both MDCT (small ka, Cyrillic = 0.80, p < 0.001) and MR (small ka, Cyrillic = 0.84, p < 0.001) demonstrated excellent agreement in correctly assessing the mechanisms of AR, i.e. aortic root dilatation (type I), cusp prolapse (type II) and restrictive cusp motion (type III), using surgical inspection as a reference. Measurement of ARO by both MDCT and MR allows accurate quantitative assessment of AR. Both techniques can also accurately determine the mechanism of AR.

Document type Article de périodique (Journal article) – Article de recherche – Journal Article, Research Support, Non-U.S. Gov't
Access type Accès restreint
Publication date 2010
Language Anglais
Journal information "European radiology" - Vol. 20, no. 2, p. 326-36 (2010)
Peer reviewed yes
issn 0938-7994
Publication status Publié
Affiliations UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire
UCL - (SLuc) Service de cardiologie
MESH Subject Tomography, X-Ray Computed - methods ; Subtraction Technique ; Sensitivity and Specificity ; Reproducibility of Results ; Middle Aged ; Male ; Magnetic Resonance Angiography - methods ; Humans ; Female ; Aortography - methods ; Aortic Valve Insufficiency - diagnosis ; Aged ; Adult
Links
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Bibliographic reference Goffinet, Céline ; Kersten, Valérie ; Pouleur, Anne-Catherine ; Le Polain De Waroux, Jean-Benoît ; Vancraeynest, David ; et. al. Comprehensive assessment of the severity and mechanism of aortic regurgitation using multidetector CT and MR.. In: European radiology, Vol. 20, no. 2, p. 326-36 (2010)
Permanent URL http://hdl.handle.net/2078.1/26639