Horsmans, Yves
[UCL]
Rahier, Jacques
[UCL]
Geubel, André
[UCL]
A 67-year-old patient, with primary polymyositis and without previous evidence of liver disease, developed clinical and biochemical features of severe cholestasis 3 months after initiation of azathioprine therapy. Liver biopsy showed cholestasis with both cytological and architectural alterations of interlobular bile ducts. Azathioprine withdrawal resulted after 7 weeks in the resolution of clinical and biochemical abnormalities. It is believed that this is the first reported case of reversible azathioprine-induced cholestasis associated with histological evidence of bile duct injury.
Bibliographic reference |
Horsmans, Yves ; Rahier, Jacques ; Geubel, André. Reversible cholestasis with bile duct injury following azathioprine therapy. A case report.. In: Liver, Vol. 11, no. 2, p. 89-93 (1991) |
Permanent URL |
http://hdl.handle.net/2078.1/26400 |