Treatment with Micafungin in a Preterm Neonate with an Invasive Infection after a Severe Terlipressin-Induced Skin Necrosis.

De Rose, Domenico Umberto Piersigilli, Fiammetta [UCL] Goffredo, Bianca Maria Danhaive, Olivier [UCL] Dotta, Andrea Auriti, Cinzia

infections are increasingly reported in preterm neonates, but the optimal treatment remains uncertain. We report the clinical history of an extremely preterm neonate, who developed a devastating skin necrosis due to terlipressin administration, with subsequent superinfection by . The infant underwent multiple curettages and skin grafts to resolve skin lesions and was treated with systemic micafungin administration at a high dose (8 mg/kg/day), with resolution of the fungal infection.