Use of calixarenes bearing diazonium groups for the development of robust monolayers with unique tailored properties

Troian-Gautier, Ludovic [UCL] Mattiuzzi, Alice Reinaud, Olivia Lagrost, Corinne Jabin, Ivan

Surface modification represents an active field of research that finds applications, amongst others, in the development of medical devices, sensors and biosensors, anti-biofouling materials, self-cleaning surfaces, surfaces with controlled wettability, corrosion resistance, heterogeneous catalysis and microelectronics. For some applications, surface functionalization with a nanometric-size monolayer is desired. In this review, efforts to covalently functionalize a wide array of surfaces with calixarenes bearing diazonium groups are described. More specifically, methodologies to obtain monolayers of calix[4 or 6]arene derivatives on conductive, semi-conductive or insulating surfaces as well as on nanoparticles are presented. The main advantages of this general surface modification strategy (i.e. formation of true monolayers that can be post-functionalized, high robustness and control over the composition of the calixarene-based coating) and its current scope of applications and future challenges are discussed.