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Phosphorylated neurofilament epitopes in neuronal perikarya in the septum, mesencephalon and dorsal root ganglia of mammals and birds.

Bibliographic reference Klosen, P. ; Van den Bosch de Aguilar, P. Phosphorylated neurofilament epitopes in neuronal perikarya in the septum, mesencephalon and dorsal root ganglia of mammals and birds.. In: Journal of neurocytology, Vol. 23, no. 5, p. 297-311 (1994)
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  1. Anderton, B. H., Breinburg, D., Downes, M. J., Green, P. J., Tomlinson, B. E., Ulrich, J., Wood, J. N. &Kahn, J. (1982) Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants.Nature 298, 84?6.
  2. Berglund, A. M. &Ryugo, D. K. (1986) A monoclonal antibody labels type II neurons of the spiral ganglion.Brain Research 383, 327?32.
  3. Berglund, A. M. &Ryugo, D. K. (1991) Neurofilament antibodies and spiral ganglion neurons of the mammalian cochlea.Journal of Comparative Neurology 306, 393?408.
  4. Brion, J. P., Cheetham, M. E., Couck, A. M., Flament-Durand, J., Hanger, D. P. &Anderton, B. H. (1990) Characterization of a partial cDNA specific for the high molecular weight microtubule-associated protein MAP2 that encodes epitopes shared with paired helical filaments of Alzheimer's disease.Dementia 1, 304?15.
  5. Calvert, R. &Anderton, B. H. (1982)In vivo metabolism of mammalian neurofilament polypeptides in developing and adult rat brain.FEBS Letters 145, 171?5.
  6. Carden, M. J., Schlaepfer, W. W. &Lee, V. M.-Y. (1985) The structure, biochemical properties and immunogenicity of neurofilament peripheral regions are determined by phosphorylation state.Journal of Biological Chemistry 260, 9805?17.
  7. Coleman, M. P. &Anderton, B. H. (1990) Phosphatedependent monoclonal antibodies to neurofilaments and Alzheimer neurofibrillary tangles recognize a synthetic phosphopeptide.Journal of Neurochemistry 54, 1548?55.
  8. Cork, L. C., Troncoso, J. C., Klavano, G. G., Johnson, E. S., Sternberger, L. A., Sternberger, N. H. &Price, D. L. (1988) Neurofilamentous abnormalities in motor neurons in spontaneously occurring animal disorders.Journal of Neuropathology and Experimental Neurology 47, 420?31.
  9. Dahl, D., Labkovsky, B. &Bignami, A. (1988) Neurofilament phosphorylation in axons and perikarya: immuno-fluorescence study of the rat spinal cord and dorsal root ganglia with monoclonal antibodies.Journal of Comparative Neurology 271, 445?50.
  10. Debus, E., Weber, K. &Osborn, M. (1983) Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and each of the neurofilament triplet polypeptides.Differentiation,25, 193?203.
  11. Dickson, D. W., Yen, S.-M., Suzuki, K. I., Davies, P. &Garcia, J. H. (1986) Ballooned neurons in select neuro-degenerative diseases contain phosphorylated neurofilament epitopes.Acta Neuropathologica 71, 216?23.
  12. Doucet, J.-P., Murphy, B. J. &Tuana, B. S. (1990) Modification of a discontinuous and highly porous sodium dodecyl sulfate-polyacrylamide gel system for minigel electrophoresis.Analytical Biochemistry 190, 209?11.
  13. Eaker, E. Y., Shaw, G. &Sninsky, C. A. (1990) Neurofilament immunoreactivity in myenteric neurons differs from that found in the central nervous system.Gastroenterology 99, 1364?71.
  14. Geisler, N., Kaufman, E., Fisher, S., Pleasmann, U. &Weber, K. (1983) Neurofilament structure combines structural principles of intermediate filaments with carboxy-terminal extensions increasing in size between triplet proteins.EMBO Journal 2, 1295?302.
  15. Glicksman, M. A., Soppet, D. &Willard, M. B. (1987) Posttranslational modification of neurofilament polypeptides in rabbit retina.Journal of Neurobiology 18, 167?96.
  16. Goldstein, M. E., Cooper, H. S., Bruce, J., Carden, M. J., Lee, V. M. Y. &Schlaepfer, W. W. (1987) Phosphorylation of neurofilament proteins and chromatolysis following transection of rat sciatic nerve.Journal of Neuroscience 7, 1586?94.
  17. Griffiths, I. R., Lusk, S. A., Kyriakides, E. &Smith, S. (1993) Neurones in autonomic ganglia of normal horses contain phosphorylated neurofilaments.Journal of Comparative Pathology 108, 109?12.
  18. Hauch, M. C., Probst, A., Ulrich, J., Kahn, J. &Anderton, B. H. (1986) Alzheimer neurofibrillary tangles contain phosphorylated and hidden neurofilament epitppes.Journal of Neurology, Neurosurgery and Psychiatry 49, 1213?20.
  19. Itoh, T., Sobue, G., Ken, E., Mitsuma, T., Takahashi, A. &Trojanowski, J. Q. (1992) Phosphorylated high molecular weight neurofilament protein in the peripheral motor, sensory and sympathetic neuronal perikarya: system-dependent normal variations and changes in amyotrophic lateral sclerosis and multiple system atrophy.Acta Neuropathologica 83, 240?5.
  20. Kai-Kai, M. A., Anderton, B. H. &Keen, P. (1986) A quantitative analysis of the interrelationships between subpopulations of rat sensory neurons containing arginine vasopressin or oxytocin and that containing substance P, fluoride-resistant acid phosphatase or neurofilament protein.Neuroscience 18, 475?86.
  21. Klosen, P., Goemaere-Vanneste, J., Terao, E. &Van Den Bosch De Aguilar, P. (1989) Approche expérimentale des manifestations de la démence sénile.Acta Neurologica Belgica 89, 294?9.
  22. Klosen, P., Anderton, B. H., Brion, J.-P. &Van Den Bosch De Aguilar, P. (1990) Perikaryal neurofilament phosphorylation in axotomized and 6-OH-dopaminelesioned CNS neurons.Brain Research 526, 259?69.
  23. Klosen, P. &Van Den Bosch De Aguilar, P. (1992) Spontaneous perikaryal neurofilament phosphorylation in the septofimbrial nucleus of the rat.Neuroscience Letters 139, 108?13.
  24. Klosen P, Maessen X, van den Bosch de Aguilar P, PEG embedding for immunocytochemistry: application to the analysis of immunoreactivity loss during histological processing., 10.1177/41.3.8429209
  25. Koliatsos, V. E., Applegate, M. D., Kitt, C. A., Walker, L. C., De Long, M. R. &Price, D. L. (1989) Aberrant phosphorylation of neurofilaments accompanies transmitter-related changes in rat septal neurons following transection of the fimbria-fornix.Brain Research 482, 205?18.
  26. Ksiezak-Reding, H., Dickson, D. W., Davies, P. &Yen, S. H. (1987) Recognition of tau epitopes by anti-neurofilament antibodies that bind to Alzheimer neurofibrillary tangles.Proceedings of the National Academy of the Sciences (USA) 84, 3410?14.
  27. Lawson, S. N., Harper, A. A., Harper, E. I., Garson, J. A. &Anderton, B. H. (1984) A monoclonal antibody against neurofilament protein specifically labels a sub-population of rat sensory neurons.Journal of Comparative Neurology 228, 263?72.
  28. Lee, V. M.-Y., Carden, M. J., Schlaepfer, W. W. &Trojanowski, J. Q. (1987) Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats.Journal of Neuroscience 7, 3474?88.
  29. Lewis, S. A. &Nixon, R. A. (1988) Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments.Journal of Cell Biology 107, 2689?701.
  30. Manetto, V., Sternberger, N. H., Perry, G., Sternberger, L. A. &Gambetti, P. (1988) Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis.Journal of Neuropathology and Experimental Neurology 47, 642?53.
  31. Martin, J. E., Mather, K. S., Swash, M., Garofalo, O., Dale, G. E., Leigh, P. N. &Anderton, B. H. (1990) Spinal cord trauma in man: studies of phosphorylated neurofilament and ubiquitin expression.Brain 113, 1553?62.
  32. Mclean, I. &Nakane, P. K. (1974) Periodate-lysine-paraformaldehyde fixative ? a new fixative for immuno-electron-microscopy.Journal of Histochemistry and Cytochemistry 22, 1077?83.
  33. Miller, C. C. J., Brion, J. P., Calvert, R., Chin, T. K., Eagles, P. A. M., Downes, M. J., Flament-Durand, J., Hauch, M., Kahn, J., Probst, A., Ulrich, J. &Anderton, B. H. (1986) Alzheimer's paired helical filaments share epitopes with neurofilament side arms.EMBO Journal 5, 269?76.
  34. Moss, T. H. &Lewkowicz, S. J. (1983) The axon reaction in motor and sensory neurones of mice studied by a monoclonal antibody marker of neurofilament protein.Journal of Neurological Sciences 60, 267?80.
  35. Munoz, D. G., Greene, C., Perl, D. P. &Selkoe, D. J. (1988) Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients.Journal of Neuropathology and Experimental Neurology 47, 9?18.
  36. Nakazato, Y., Hirato, J., Ishida, Y., Hoshi, S., Hasegawa, M. &Fukuda, T. (1990) Swollen cortical neurons in Creutzfeldt-Jakob disease contain a phosphorylated neurofilament epitope.Journal of Neuropathology and Experimental Neurology 49, 197?205.
  37. Nixon, R. A., Brown, B. A. &Marotta, C. A. (1982) Posttranslational modification of a neurofilament protein during axonal transport: implications for regional specialization of CNS axons.Journal of Cell Biology 94, 150?8.
  38. Nixon, R. A. &Lewis, S. E. (1986) Differential turnover of phosphate groups on neurofilament subunits in mammalian neuronsin vivo.Journal of Biological Chemistry 261, 16298?301.
  39. Nixon, R. A., Lewis, S. E., Dahl, D., Marotta, C. A. &Draeger, U. C. (1989) Early posttranslational modifications of the three neurofilament subunits in mouse retinal ganglion cells: neuronal site and time course in relation to subunit polymerization and axonal transport.Molecular Brain Research 5, 93?108.
  40. Nukina, N., Kosik, K. S. &Selkoe, D. J. (1987) Recognition of Alzheimer paired helical filaments by monoclonal neurofilament antibodies is due to crossreaction with tau protein.Proceedings of the National Academy of the Sciences (USA) 84, 3415?19.
  41. Perry, M. J., Lawson, S. N. &Robertson, J. (1991) Neurofilament immunoreactivity in populations of rat primary afferent neurons: a quantitative study of phosphorylated and non-phosphorylated subunits.Journal of Neurocytology 20, 746?58.
  42. Perry, M. J. &Lawson, S. N. (1993) Neurofilament in feline primary afferent neurones: a quantitative immunocytochemical study.Brain Research 607, 307?13.
  43. Poltorak, M. &Freed, W. J. (1987) Normal neuronal cell bodies of the nucleus tractus mesencephalici nervi trigemini react with antibodies against phosphorylated epitopes on neurofilaments.Experimental Neurology 97, 735?8.
  44. Romand, R., Hafidi, A. &Despres, G. (1988) Immunocytochemical localization of neurofilament protein subunits in the spiral ganglion of the rat.Brain Research 462, 167?73.
  45. Rosenfeld, J., Dorman, M. E., Griffin, J. W., Sternberger, L. A., Sternberger, N. H. &Price, D. L. (1987) Distribution of neurofilament antigens after axonal injury.Journal of Neuropathology and Experimental Neurology 46, 269?82.
  46. Shaw, G., Debus, E. &Weber, K. (1984) The immunological relatedness of neurofilament proteins of higher vertebrates.European Journal of Cell Biology 34, 130?6.
  47. Shaw, G., Osborn, M. &Weber, K. (1986) Reactivity of a panel of neurofilament antibodies on phosphorylated and dephosphorylated neurofilaments.European Journal of Cell Biology 42, 1?9.
  48. Shaw, G., Winialski, D. &Reier, P. (1988) The effect of axotomy and deafferentation on phosphorylation dependent antigenicity of neurofilaments in rat superior cervical ganglion neurons.Brain Research 460, 227?34.
  49. Shaw, G. (1991) Neurofilament proteins. InThe Neuronal Cytoskeleton (edited byBurgoyne, R. D.) pp. 185?214. New York: Wiley-Liss.
  50. Soppet, D. R., Beasley, L. L. &Willard, M. B. (1992) Evidence for unequal crossing over in the evolution of the neurofilament polypeptide H.Journal of Biological Chemistry 267, 17354?61.
  51. Sternberger, L. A. &Sternberger, N. H. (1983) Monoclonal antibodies distinguish phosphorylated and non-phosphorylated forms of neurofilamentsin situ.Proceedings of the National Academy of the Sciences (USA) 80, 6126?30.
  52. Toyoshima, I., Yamamoto, A. &Satake, M. (1988) Processing of neurofilament proteins from perikaryal to axonal type.Neurochemical Research 13, 621?4.
  53. Towbin, H., Staehelin, T. &Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.Proceedings of the National Academy of the Sciences (USA) 76, 4350?4.
  54. Van Den Bosch De Aguilar, P. &Vanneste, J. (1981) Etude ultrastructurale des neurones ganglionaires spinaux au cours du vieillissement chez le rat.Acta Anatomica 110, 59?70.
  55. Van Den Bosch De Aguilar, P. &Goemaere-Vanneste, J. (1984) Paired helical filaments in spinal ganglion neurons of elderly rats.Virchows Archiv B (Cellular Pathology) 47, 217?22.
  56. Van Den Bosch De Aguilar, P., Goemaere-Vanneste, J., Klosen, P. &Terao, E. (1992) Ageing changes of spinal ganglion neurons. InDevelopment and Involution of Neurones (edited byFujisawa, K. &Morimatsu, Y.) pp. 111?51. Tokyo: Japan Scientific Societies Press.
  57. Vickers, J. C., Costa, M., Vitadello, M., Dahl, D. &Marotta, C. A. (1990) Neurofilament protein-triplet immunoreactivity in distinct subpopulations of peptide-containing neurons in the guinea-pig coeliac ganglion.Neuroscience 39, 743?59.
  58. Vickers, J. C. &Costa, M. (1991) Neurofilament protein triplet immunoreactivity in the dorsal root ganglia of the guinea-pig.Cell and Tissue Research 265, 159?67.
  59. Willard, M. B. (1976) Genetically determined protein polymorphism in the rabbit nervous system.Proceedings of the National Academy of the Sciences (USA) 73, 3641?5.
  60. Zaman, Z. &Verwilghen, R. L. (1979) Quantitation of proteins solubilized in sodium dodecyl sulfate-mercaptoethanol-tris electrophoresis buffer.Analytical Biochemistry 100, 64?9.