User menu

Glucuronidation of diflunisal in liver and kidney microsomes of rat and man.

Bibliographic reference Brunelle, F M ; Verbeeck, Roger-K.. Glucuronidation of diflunisal in liver and kidney microsomes of rat and man.. In: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 26, no. 2, p. 123-31 (1996)
Permanent URL
  1. Amar-Costesec A., ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER: II. Preparation and Composition of the Microsomal Fraction, 10.1083/jcb.61.1.201
  2. Brunelle F. M., Biopharmaceutics and Drug Disposition (1996)
  3. Brunelle Fraçoise M., Verbeeck Roger K., Glucuronidation of diflunisal by rat liver microsomes, 10.1016/0006-2952(93)90636-b
  4. Cappiello M., Giuliani L., Pacifici G. M., Distribution of UDP-glucuronosyltransferase and its endogenous substrate uridine 5?-diphosphoglucuronic acid in human tissues, 10.1007/bf00314965
  5. Clarke D. J., Burchell B., The Uridine Diphosphate Glucuronosyltransferase Multigene Family: Function and Regulation, Handbook of Experimental Pharmacology (1994) ISBN:9783642784316 p.3-43, 10.1007/978-3-642-78429-3_1
  6. Dickinson Ronald G., King Andrew R., Reactivity Considerations in the Analysis of Glucuronide and Sulfate Conjugates of Diflunisal : , 10.1097/00007691-198911000-00018
  7. Dickinson R. G., Verbeeck R. K., King A. R., Absence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat, 10.3109/00498259109044403
  8. Dutton G. J, Glucuronidation of Drugs and Other Compounds (1980)
  9. Dwivedi C., FASEB Journal, 1, 303 (1987)
  10. Ebner T., Drug Metabolism and Disposition, 21, 50 (1993)
  11. Fevery J, Van de Vijver M, Michiels R, Heirwegh K P M, Comparison in different species of biliary bilirubin-IX α conjugates with the activities of hepatic and renal bilirubin-IX α-uridine diphosphate glycosyltransferases, 10.1042/bj1640737
  12. Green M. D., Drug Metabolism and Disposition, 23, 299 (1995)
  13. Heirwegh K. P. M., Van De Vijver M., Fevery J., Assay and properties of digitonin-activated bilirubin uridine diphosphate glucuronyltransferase from rat liver, 10.1042/bj1290605
  14. Kauffman F. C., Regulation of Drug Conjugate Production by Futile Cycling in Intact Cells, Handbook of Experimental Pharmacology (1994) ISBN:9783642784316 p.245-255, 10.1007/978-3-642-78429-3_9
  15. Krishna Devarakonda R., Klotz Ulrich, Extrahepatic Metabolism of Drugs in Humans : , 10.2165/00003088-199426020-00007
  16. Kroemer Heyo K., Klotz Ulrich, Glucuronidation of Drugs : A Re-Evaluation of the Pharmacological Significance of the Conjugates and Modulating Factors, 10.2165/00003088-199223040-00005
  17. Lear L., Nation R.L., Stupans I., Influence of morphine concentration on detergent activation of rat liver morphine-UDP-glucuronosyltransferase, 10.1016/0006-2952(91)90392-i
  18. Lin J. H., Journal of Pharmacology and Experimental Therapeutics, 235, 402 (1985)
  19. Loewen Gordon R., Macdonald James I., Verbeeck Roger K., High-Performance Liquid Chromatographic Method for the Simultaneous Quantitation of Diflunisal and its Glucuronide and Sulfate Conjugates in Human Urine, 10.1002/jps.2600780317
  20. Lowry O. H., Journal of Biological Chemistry, 193, 265 (1951)
  21. Marselos Marios, Dutton Geoffrey, Hänninen Osmo, Evidence that d-glucaro-1,4-lactone shortens the pharmacological action of drugs being disposed via the bile as glucuronides, 10.1016/0006-2952(75)90403-7
  22. Mazoit Jean Xavier, Sandouk Pierre, Scherrmann Jean-Michel, Roche Alain, Extrahepatic metabolism of morphine occurs in humans, 10.1038/clpt.1990.203
  23. Miners John O., Mackenzie Peter I., Drug glucuronidation in humans, 10.1016/0163-7258(91)90065-t
  24. Mulder G J, Glucuronidation and its Role in Regulation of Biological Activity of Drugs, 10.1146/
  25. Mulder G J, van Doorn A B, A rapid NAD+-linked assay for microsomal uridine diphosphate glucuronyltransferase of rat liver and some observations on substrate specificity of the enzyme, 10.1042/bj1510131
  26. Pritchard M., Molecular Pharmacology, 45, 42 (1994)
  27. Spahn-Langguth Hildegard, Benet Leslie Z., MicrosomalAcyl Glucuronidation: Enzyme-Kinetic Studies with Labile Glucuronides, 10.1159/000139054
  28. Sutherland Lesley, Ebner Thomas, Burchell Brian, The expression of UDP-glucuronosyltransferases of the UGT1 family in human liver and kidney and in response to drugs, 10.1016/0006-2952(93)90064-4
  29. Tocco D. J., Drug Metabolism and Disposition, 6, 453 (1975)
  30. Tomašić J., Keglević D., The kinetics of hydrolysis of synthetic glucuronic esters and glucuronic ethers by bovine liver andEscherichia coliβ-glucuronidase, 10.1042/bj1330789
  31. Verbeeck RK, Loewen GR, MacDonald JI, Herman RJ, The effect of multiple dosage on the kinetics of glucuronidation and sulphation of diflunisal in man., 10.1111/j.1365-2125.1990.tb03654.x
  32. Walaszek Z., Potential use of d-glucaric acid derivatives in cancer prevention, 10.1016/0304-3835(90)90083-a
  33. Walaszek Zbigniew, Hanausek-Walaszek Malgorzata, Webb Thomas E., Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumorigenesis by 2,5-di-O-acetyl-D-glucaro-1, 4:6,3-dilactone, an in vivo β-glucuronidase inhibitor, 10.1093/carcin/5.6.767
  34. Walaszek Zbigniew, Hanausek-Walaszek Malgorzata, Webb Thomas E., Dietary glucarate-mediated reduction of sensitivity of murine strains to chemical carcinogenesis, 10.1016/0304-3835(86)90098-4
  35. Whiting J. F., Journal of Biological Chemistry, 268, 23197 (1993)