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Chilblains and COVID-19: why SARS-CoV-2 endothelial infection is questioned.

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Baeck, Marie [UCL] Hoton, Delphine [UCL] Marot, Liliane [UCL] Herman, Anne [UCL]

Recently, Colmenero et al (1) demonstrated, by immunohistochemistry, the presence of SARS‐CoV‐2 in endothelial cells of skin biopsy specimens of chilblains in seven patients. These results raise some questions: The presence of the virus at cutaneous and vascular levels in otherwise asymptomatic patients with negative RT‐PCR is unexpected. Vascular damage by direct viral effect is expected to be a sign of severity. It is also surprising that only feet are affected.

Document type Article de périodique (Journal article) – Lettre à l'éditeur
Access type Accès libre
Publication date 2020
Language Anglais
Journal information "The British journal of dermatology" - Vol. 183, no.6, p. 1152-1153 (2020)
Peer reviewed yes
Publisher Blackwell Scientific Publications ((United Kingdom) Oxford)
issn 0007-0963
e-issn 1365-2133
Publication status Publié
Affiliations UCL - SSS/IREC/LUNS - Pôle pneumologie, ORL (airways) et dermatologie (skin)
UCL - SSS/IREC/SLUC - Pôle St.-Luc
UCL - (SLuc) Service de dermatologie
UCL - (SLuc) Service d'anatomie pathologique
MESH Subject COVID-19 ; Chilblains ; Child ; Humans ; Risk Factors ; SARS-CoV-2
Links
Bibliographic reference Baeck, Marie ; Hoton, Delphine ; Marot, Liliane ; Herman, Anne. Chilblains and COVID-19: why SARS-CoV-2 endothelial infection is questioned.. In: The British journal of dermatology, Vol. 183, no.6, p. 1152-1153 (2020)
Permanent URL http://hdl.handle.net/2078.1/243420