Poncin, William
[UCL]
Rombaut, Samy
[UCL]
Macedo, Juliana
Reychler, Gregory
[UCL]
Liistro, Giuseppe
[UCL]
BACKGROUND: SIMEOX produces a non-invasive succession of very short air depressions through a mouthpiece During expiration. Therefore, the SIMEOX technology claims to reduce expiratory flow limitation. OBJECTIVE: To assess the safety and to measure expiratory volume and flow mobilized with SIMEOX. METHODS: Non-smoker adults with no history of cardio-respiratory disease were recruited. Each participant performed 3 slow vital capacity (VC) maneuvers followed by 3 slow maximal exhalations from total lung capacity with SIMEOX. Flow and volume were measured using a pneumotachograph. The highest volume of each attempt was reported while flow was averaged from the 3 repetitions. Participants were further Categorized according to the lower limit of normality (LLN) of VC calculated from ERS 1993 equations. RESULTS: Thirty-two subjects (21F, 24 ± 8y) were recruited. Mean (±SD) volume during slow expiration with SIMEOX and slow VC was respectively 4.01 ± 0.93L and 4.05 ± 1.08L (p=0.55). Mean expiratory flow with SIMEOX was significantly lower than during slow VC (0.8 ± 0.1L/s vs 2 ± 0.9L/s, p<0.001). Twenty-three subjects had a VC higher than LLN. In these subjects, SIMEOX yielded a lower expiratory volume than slow VC (mean difference = -0.15 ± 0.29L, p=0.02). Conversely, the remaining 9 subjects (median [range] VC%pred = 73% [48-82%]) exhaled significantly more volume with SIMEOX (median [range] difference = 0.22L [-0.18 – 0.68], p=0.02). No adverse effect was observed. CONCLUSIONS: Our preliminary data suggest that SIMEOX modifies the expiratory pattern and may be able to mobilize an extra volume of air in subjects with abnormal lung function. Collection of data in patients with COPD is ongoing.


Bibliographic reference |
Poncin, William ; Rombaut, Samy ; Macedo, Juliana ; Reychler, Gregory ; Liistro, Giuseppe. Assessment of a new airway clearance technology on maximal slow expiratory volume.ERS International Congress 2019 ((Spain) Madrid, du 28/09/2019 au 02/10/2019). |
Permanent URL |
http://hdl.handle.net/2078.1/240777 |