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The role of Dopamine in Preparatory Inhibition: What can we learn from Parkinson’s disease?

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Wilhelm, Emmanuelle [UCL] Quoilin, Caroline [UCL] Derosiere, Gerard [UCL] Jeanjean, Anne Duque, Julie [UCL]

Recent transcranial magnetic stimulation studies have shown that the motor output pathway shows a profound inhibition during the preparation of an action. This phenomenon, called “preparatory inhibition”, remains incompletely understood, as it is still unclear which neural structures support it and what function it exactly serves during action preparation. In the current study, we tested this preparatory inhibition in Parkinson’s disease (PD) patients and matched healthy control subjects. The aim was to better understand the role of basal ganglia (which are dysfunctional in PD) and the influence of dopamine replacement therapy on motor inhibition during action preparation.

Document type Communication à un colloque (Conference Paper) – Présentation orale avec comité de sélection, Abstract
Access type Accès libre
Publication date 2018
Language Anglais
Conference "Belgian Brain Congress 2018", Liège (19/10/2018)
Journal information "Front. Neurosci. Belgian Brain Congress 2018" - Vol. 1, no.1, p. 1 (2018)
Peer reviewed yes
issn 1662-4548
e-issn 1662-4548
Publisher Frontiers Research Foundation (Switzerland (Lausanne))
Publication status Publié
Affiliation UCL - SSS/IONS/COSY - Systems & cognitive Neuroscience
Links
Bibliographic reference Wilhelm, Emmanuelle ; Quoilin, Caroline ; Derosiere, Gerard ; Jeanjean, Anne ; Duque, Julie. The role of Dopamine in Preparatory Inhibition: What can we learn from Parkinson’s disease?.Belgian Brain Congress 2018 (Liège, 19/10/2018). In: Front. Neurosci. Belgian Brain Congress 2018, Vol. 1, no.1, p. 1 (2018)
Permanent URL http://hdl.handle.net/2078.1/240143