User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

IL-22 inhibitors to treat inflammatory disorders such as arthritis

Primary tabs

Renauld, Jean-Christophe [UCL]

IL-22 is a recently described cytokine showing 23% amino acid identity with IL-10, and which has been previously shown to induce the production of acute phase proteins in liver and pancreas, suggesting a role in inflammatory responses. This patent application claims agents that modulate IL-22 activity useful as modulators of a large panel of inflammatory disorders, including autoimmune diseases, cancer and sepsis. More particularly, anti-IL-22 antibodies are reported to inhibit arthritis in a mouse model.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2005
Language Anglais
Journal information "Expert Opinion on Therapeutic Patents" - Vol. 13, no.3, p. 373-375 (2003)
Peer reviewed yes
Publisher Informa Healthcare (London)
issn 1354-3776
e-issn 1744-7674
Publication status Publié
Affiliation UCL - MD/MIGE - Département de microbiologie, d'immunologie et de génétique
Keywords Cytokines ; IL-22 ; Inflammation ; Rheumatoid arthritis
Links
Bibliographic reference Renauld, Jean-Christophe. IL-22 inhibitors to treat inflammatory disorders such as arthritis. In: Expert Opinion on Therapeutic Patents, Vol. 13, no.3, p. 373-375 (2003)
Permanent URL http://hdl.handle.net/2078.1/239123