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Future of Renal Sympathetic Denervation in the Treatment of Hypertension

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Kjeldsen, Sverre E. Fadl Elmula, Fadl E.M. Persu, Alexandre [UCL]

(eng) In this issue of the Journal, Sardar et al. (1) report the results of a meta-analysis evaluating the blood pressure (BP) response to renal sympathetic denervation (RSD) in 6 sham-controlled randomized clinical trials including 3 recently published trials and totaling 977 patients. Compared with sham control, RSD significantly reduced both systolic and diastolic office, 24-h ambulatory, and daytime BP. The authors conclude that these results should guide the design of larger, pivotal trials to evaluate the long-term efficacy and safety of RSD in patients with uncontrolled and resistant hypertension. [...]

Document type Article de périodique (Journal article) – Éditorial
Access type Accès libre
Publication date 2019
Language Anglais
Journal information "Journal of the American College of Cardiology" - Vol. 73, no. 13, p. 1643-1645 (2019)
Peer reviewed yes
Publisher Elsevier Biomedical ((United States) New York, NY)
issn 0735-1097
e-issn 1558-3597
Publication status Publié
Affiliations UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire
UCL - (SLuc) Service de cardiologie
Keywords Cardiology and Cardiovascular Medicine ; Blood pressure ; Hypertension ; Renal arteries ; Renal nerves ; Sympathetic ablation ; Sympathetic activity
Links
Bibliographic reference Kjeldsen, Sverre E. ; Fadl Elmula, Fadl E.M. ; Persu, Alexandre. Future of Renal Sympathetic Denervation in the Treatment of Hypertension. In: Journal of the American College of Cardiology, Vol. 73, no. 13, p. 1643-1645 (2019)
Permanent URL http://hdl.handle.net/2078.1/230865