User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Efficient Construction of Polycyclic Derivatives via a Highly Selective Cu(I)-Catalyzed Domino Reductive-Aldol Cyclization.

Primary tabs

Deschamp, Julia Olivia [UCL] Riant, Olivier [UCL]

A versatile methodology for the diastereo- and enantioselective domino reductive-aldol cyclizations is reported. By using a copper (I)/diphosphane ligand, various five- and six-membered rings were generated with good to excellent diastereo- and enantioselectivities (cis:trans up to 100:0 and ee up to 95%).

Document type Article de périodique (Journal article) – Journal Article, Research Support, Non-U.S. Gov't
Access type Accès restreint
Publication date 2009
Journal information "Organic letters" - Vol. 11, no. 6, p. 1217-20 (2009)
Peer reviewed yes
issn 1523-7060
e-issn 1523-7052
Affiliation UCL - SC/CHIM - Département de chimie
MESH Subject Stereoisomerism ; Polycyclic Compounds - chemical synthesis - chemistry ; Phosphines - chemistry ; Oxidation-Reduction ; Molecular Structure ; Iodides - chemistry ; Cyclization ; Copper - chemistry ; Catalysis ; Aldehydes - chemistry
Links
Bibliographic reference Deschamp, Julia Olivia ; Riant, Olivier. Efficient Construction of Polycyclic Derivatives via a Highly Selective Cu(I)-Catalyzed Domino Reductive-Aldol Cyclization.. In: Organic letters, Vol. 11, no. 6, p. 1217-20 (2009)
Permanent URL http://hdl.handle.net/2078.1/21463