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Spontaneous ascending aortic intramural haematoma in a patient on dabigatran.

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Mastrobuoni, Stefano [UCL] Robblee, James A Boodhwani, Munir

A patient on oral anticoagulation with dabigatran presented with chest pain and dyspnoea. A CT scan of the chest revealed an intramural haematoma of the ascending aorta with a large pericardial effusion. The patient underwent a modified Bentall procedure. In the absence of a specific antidote for this novel oral anticoagulant medication, even in an emergency situation, successful surgical treatment was possible with an aggressive use of available prohaemostatic agents.

Document type Article de périodique (Journal article)
Publication date 2012
Language Anglais
Journal information "Interactive cardiovascular and thoracic surgery" - Vol. 15, no.2, p. 299-300 (2012)
Peer reviewed yes
e-issn 1569-9285
Publication status Publié
Affiliation UCL - SSS/IREC - Institut de recherche expérimentale et clinique
MESH Subject Administration, Oral ; Aged ; Anticoagulants ; Aortic Diseases ; Aortic Valve ; Benzimidazoles ; Blood Vessel Prosthesis Implantation ; Chest Pain ; Dabigatran ; Dyspnea ; Female ; Heart Valve Diseases ; Heart Valve Prosthesis Implantation ; Hematoma ; Humans ; Pericardial Effusion ; Risk Factors ; Tomography, X-Ray Computed ; Treatment Outcome ; beta-Alanine
Links
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  2. Connolly Stuart J., Ezekowitz Michael D., Yusuf Salim, Eikelboom John, Oldgren Jonas, Parekh Amit, Pogue Janice, Reilly Paul A., Themeles Ellison, Varrone Jeanne, Wang Susan, Alings Marco, Xavier Denis, Zhu Jun, Diaz Rafael, Lewis Basil S., Darius Harald, Diener Hans-Christoph, Joyner Campbell D., Wallentin Lars, Dabigatran versus Warfarin in Patients with Atrial Fibrillation, 10.1056/nejmoa0905561
  3. Thrombosis and haemostasis, 103, 116 (2010)
  4. Wann L. Samuel, Curtis Anne B., Ellenbogen Kenneth A., Estes N.A. Mark, Ezekowitz Michael D., Jackman Warren M., January Craig T., Lowe James E., Page Richard L., Slotwiner David J., Stevenson William G., Tracy Cynthia M., 2011 ACCF/AHA/HRS Focused Update on the Management of Patients With Atrial Fibrillation (Update on Dabigatran), 10.1016/j.jacc.2011.01.010
Bibliographic reference Mastrobuoni, Stefano ; Robblee, James A ; Boodhwani, Munir. Spontaneous ascending aortic intramural haematoma in a patient on dabigatran.. In: Interactive cardiovascular and thoracic surgery, Vol. 15, no.2, p. 299-300 (2012)
Permanent URL http://hdl.handle.net/2078.1/210824