| Authors |
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| Document type |
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Article de périodique (Journal article) – Case Reports, Journal Article
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| Abstract |
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The authors describe the clinical course of a 50-year-old woman who presented with life-threatening cardiac dysfunction after aneurysmal subarachnoid hemorrhage (Fisher Grade 4). The pathophysiology of cardiac injury in this setting is not fully understood, but excess sympathetic activation can lead to neurogenic stressed myocardium. A metabolic intervention using the continuous intravenous infusion of high doses of insulin with euglycemia resulted in a rapid improvement of cardiac contractility. The observed benefit could be due to better myocardial glucose utilization that could not have been achieved by catecholamine administration. |
| Publication date |
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2008 |
| Journal information |
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"Journal of neurosurgery" - Vol. 110, no. 1, p. 64-6 (2009) |
| Peer reviewed |
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yes |
| issn |
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0022-3085 |
| Publication status |
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Publié |
| Affiliation |
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UCL |
| MESH Subject |
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Troponin I - blood ; Tachycardia, Sinus - drug therapy - etiology ; Subarachnoid Hemorrhage - complications ; Myocardial Stunning - drug therapy - etiology ; Middle Aged ; Male ; Long QT Syndrome - drug therapy - etiology ; Intensive Care ; Insulin - administration & dosage - therapeutic use ; Infusions, Intravenous ; Hypoglycemic Agents - administration & dosage - therapeutic use ; Humans ; Electrocardiography ; Cardiac Output ; Blood Glucose - metabolism
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