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Contrast-enhanced nanofocus X-ray computed tomography allows virtual three-dimensional histopathology and morphometric analysis of osteoarthritis in small animal models

Bibliographic reference Kerckhofs, Greet ; Sainz, Julie ; Marechal, Marina ; Wevers, Martine ; Van de Putte, Tom ; et. al. Contrast-enhanced nanofocus X-ray computed tomography allows virtual three-dimensional histopathology and morphometric analysis of osteoarthritis in small animal models. In: Cartilage, Vol. 5, no.1, p. 55-65 (2014)
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  1. Bijlsma Johannes WJ, Berenbaum Francis, Lafeber Floris PJG, Osteoarthritis: an update with relevance for clinical practice, 10.1016/s0140-6736(11)60243-2
  2. Gelber Allan C., Joint Injury in Young Adults and Risk for Subsequent Knee and Hip Osteoarthritis, 10.7326/0003-4819-133-5-200009050-00007
  3. Messner Karola, Maletius Wolfgang, The long-term prognosis for severe damage to weight-bearing cartilage in the knee: A 14-year clinical and radiographic follow-up in 28 young athletes, 10.3109/17453679608994664
  4. Maréchal Marina, Van Hauwermeiren Hadewych, Neys Johan, Vanderlinden Gert, Van de Putte Tom, In Vivo Evaluation of Different Surgical Procedures for Autologous Chondrocyte Implantation, 10.1177/1947603512457564
  5. Christiansen B.A., Anderson M.J., Lee C.A., Williams J.C., Yik J.H.N., Haudenschild D.R., Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis, 10.1016/j.joca.2012.04.014
  6. Botter S.M., Glasson S.S., Hopkins B., Clockaerts S., Weinans H., van Leeuwen J.P.T.M., van Osch G.J.V.M., ADAMTS5−/− mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes, 10.1016/j.joca.2008.09.018
  7. Furman Bridgette D., Strand Jens, Hembree W. Chad, Ward Benjamin D., Guilak Farshid, Olson Steven A., Joint degeneration following closed intraarticular fracture in the mouse knee: A model of posttraumatic arthritis, 10.1002/jor.20331
  8. MANKIN HENRY J., DORFMAN HOWARD, LIPPIELLO LOUIS, ZARINS ANTRA, Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-Arthritic Human Hips : II. CORRELATION OF MORPHOLOGY WITH BIOCHEMICAL AND METABOLIC DATA, 10.2106/00004623-197153030-00009
  9. Glasson S.S., Chambers M.G., Van Den Berg W.B., Little C.B., The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse, 10.1016/j.joca.2010.05.025
  10. Xie L., Lin A.S.P., Levenston M.E., Guldberg R.E., Quantitative assessment of articular cartilage morphology via EPIC-μCT, 10.1016/j.joca.2008.07.015
  11. Palmer A. W., Guldberg R. E., Levenston M. E., Analysis of cartilage matrix fixed charge density and three-dimensional morphology via contrast-enhanced microcomputed tomography, 10.1073/pnas.0606406103
  12. Kotwal N., Li J., Sandy J., Plaas A., Sumner D.R., Initial application of EPIC-μCT to assess mouse articular cartilage morphology and composition: effects of aging and treadmill running, 10.1016/j.joca.2012.04.012
  13. Silvast Tuomo S., Jurvelin Jukka S., Tiitu Virpi, Quinn Thomas M., Töyräs Juha, Bath Concentration of Anionic Contrast Agents Does Not Affect Their Diffusion and Distribution in Articular Cartilage In Vitro, 10.1177/1947603512451023
  14. Bansal P.N., Stewart R.C., Entezari V., Snyder B.D., Grinstaff M.W., Contrast agent electrostatic attraction rather than repulsion to glycosaminoglycans affords a greater contrast uptake ratio and improved quantitative CT imaging in cartilage, 10.1016/j.joca.2011.04.004
  15. Xie L., Lin A.S.P., Guldberg R.E., Levenston M.E., Nondestructive assessment of sGAG content and distribution in normal and degraded rat articular cartilage via EPIC-μCT, 10.1016/j.joca.2009.07.014
  16. Kerckhofs G, , Sainz J, Wevers M, Van de Putte T, Schrooten J, Contrast-enhanced nanofocus computed tomography images the cartilage subtissue architecture in three dimensions, 10.22203/ecm.v025a13
  17. Glasson S.S., Blanchet T.J., Morris E.A., The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse, 10.1016/j.joca.2007.03.006
  18. Stewart Rachel C., Bansal Prashant N., Entezari Vahid, Lusic Hrvoje, Nazarian Rosalynn M., Snyder Brian D., Grinstaff Mark W., Contrast-enhanced CT with a High-Affinity Cationic Contrast Agent for Imaging ex Vivo Bovine, Intact ex Vivo Rabbit, and in Vivo Rabbit Cartilage, 10.1148/radiol.12112246
  19. Otsu Nobuyuki, A Threshold Selection Method from Gray-Level Histograms, 10.1109/tsmc.1979.4310076
  20. Hildebrand T., Ruegsegger P., A new method for the model-independent assessment of thickness in three-dimensional images, 10.1046/j.1365-2818.1997.1340694.x
  21. Janes K. A., A Systems Model of Signaling Identifies a Molecular Basis Set for Cytokine-Induced Apoptosis, 10.1126/science.1116598
  22. Miller-Jensen Kathryn, Janes Kevin A., Brugge Joan S., Lauffenburger Douglas A., Common effector processing mediates cell-specific responses to stimuli, 10.1038/nature06001
  23. Platt Manu O., Wilder Catera L., Wells Alan, Griffith Linda G., Lauffenburger Douglas A., Multipathway Kinase Signatures of Multipotent Stromal Cells Are Predictive for Osteogenic Differentiation : Tissue-Specific Stem Cells, 10.1002/stem.215
  24. Janes Kevin A., Kelly Jason R., Gaudet Suzanne, Albeck John G., Sorger Peter K., Lauffenburger Douglas A., Cue-Signal-Response Analysis of TNF-Induced Apoptosis by Partial Least Squares Regression of Dynamic Multivariate Data, 10.1089/cmb.2004.11.544