User menu

Chloride transporters and receptor-mediated endocytosis in the renal proximal tubule

Bibliographic reference Devuyst, Olivier ; Luciani, Alessandro. Chloride transporters and receptor-mediated endocytosis in the renal proximal tubule. In: The Journal of Physiology, Vol. 593, no.18, p. 4151-4164 (2015)
Permanent URL http://hdl.handle.net/2078.1/187514
  1. Baines Richard J., Brunskill Nigel J., Tubular toxicity of proteinuria, 10.1038/nrneph.2010.174
  2. Becker-Cohen Rachel, Rinat Choni, Ben-Shalom Efrat, Feinstein Sofia, Ivgi Heftziba, Frishberg Yaacov, Vitamin A deficiency associated with urinary retinol binding protein wasting in Dent’s disease, 10.1007/s00467-012-2121-0
  3. Bonventre J. V., Dedifferentiation and Proliferation of Surviving Epithelial Cells in Acute Renal Failure, 10.1097/01.asn.0000067652.51441.21
  4. Cheng Seng H., Gregory Richard J., Marshall John, Paul Sucharita, Souza David W., White Gary A., O'Riordan Catherine R., Smith Alan E., Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis, 10.1016/0092-8674(90)90148-8
  5. Christensen Erik Ilsø, Birn Henrik, Megalin and cubilin: multifunctional endocytic receptors, 10.1038/nrm778
  6. Christensen E. I., Devuyst O., Dom G., Nielsen R., Van Der Smissen P., Verroust P., Leruth M., Guggino W. B., Courtoy P. J., Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules, 10.1073/pnas.1432873100
  7. Coudroy G., Contribution of Cubilin and Amnionless to Processing and Membrane Targeting of Cubilin-Amnionless Complex, 10.1681/asn.2004110925
  8. De Angeli A., Monachello D., Ephritikhine G., Frachisse J. M., Thomine S., Gambale F., Barbier-Brygoo H., The nitrate/proton antiporter AtCLCa mediates nitrate accumulation in plant vacuoles, 10.1038/nature05013
  9. Devuyst, Am J Physiol Renal Physiol, 271, F723 (1996)
  10. Devuyst O, Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease, 10.1093/hmg/8.2.247
  11. Devuyst Olivier, Knoers Nine V A M, Remuzzi Giuseppe, Schaefer Franz, Rare inherited kidney diseases: challenges, opportunities, and perspectives, 10.1016/s0140-6736(14)60659-0
  12. Devuyst O., Pirson Y., Genetics of hypercalciuric stone forming diseases, 10.1038/sj.ki.5002441
  13. Devuyst Olivier, Thakker Rajesh V, Dent's disease, 10.1186/1750-1172-5-28
  14. Dickson L. E., Wagner M. C., Sandoval R. M., Molitoris B. A., The Proximal Tubule and Albuminuria: Really!, 10.1681/asn.2013090950
  15. Dutzler Raimund, Campbell Ernest B., Cadene Martine, Chait Brian T., MacKinnon Roderick, X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity, 10.1038/415287a
  16. Eckardt Kai-Uwe, Coresh Josef, Devuyst Olivier, Johnson Richard J, Köttgen Anna, Levey Andrew S, Levin Adeera, Evolving importance of kidney disease: from subspecialty to global health burden, 10.1016/s0140-6736(13)60439-0
  17. Erdmann Kai S., Mao Yuxin, McCrea Heather J., Zoncu Roberto, Lee Sangyoon, Paradise Summer, Modregger Jan, Biemesderfer Daniel, Toomre Derek, De Camilli Pietro, A Role of the Lowe Syndrome Protein OCRL in Early Steps of the Endocytic Pathway, 10.1016/j.devcel.2007.08.004
  18. Faundez, Sci STKE, 2004, re8 (2004)
  19. Feng L., Campbell E. B., Hsiung Y., MacKinnon R., Structure of a Eukaryotic CLC Transporter Defines an Intermediate State in the Transport Cycle, 10.1126/science.1195230
  20. Fyfe J. C., The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless, 10.1182/blood-2003-08-2852
  21. Gadsby David C., Vergani Paola, Csanády László, The ABC protein turned chloride channel whose failure causes cystic fibrosis, 10.1038/nature04712
  22. Gailly P., Jouret F., Martin D., Debaix H., Parreira K.S., Nishita T., Blanchard A., Antignac C., Willnow T.E., Courtoy P.J., Scheinman S.J., Christensen E.I., Devuyst O., A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunction, 10.1038/sj.ki.5002794
  23. Gekle Michael, RENAL TUBULE ALBUMIN TRANSPORT, 10.1146/annurev.physiol.67.031103.154845
  24. Gorvin C. M., Wilmer M. J., Piret S. E., Harding B., van den Heuvel L. P., Wrong O., Jat P. S., Lippiat J. D., Levtchenko E. N., Thakker R. V., Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients, 10.1073/pnas.1302063110
  25. Gunther W., Luchow A., Cluzeaud F., Vandewalle A., Jentsch T. J., ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells, 10.1073/pnas.95.14.8075
  26. Günther Willy, Piwon Nils, Jentsch Thomas J., The ClC-5 chloride channel knock-out mouse – an animal model for Dent's disease, 10.1007/s00424-002-0950-6
  27. Guggino William B., Stanton Bruce A., New insights into cystic fibrosis: molecular switches that regulate CFTR, 10.1038/nrm1949
  28. Herak-Kramberger Carol M., Brown Dennis, Sabolić Ivan, Cadmium inhibits vacuolar H+-ATPase and endocytosis in rat kidney cortex, 10.1046/j.1523-1755.1998.00914.x
  29. Hoopes Richard R., Shrimpton Antony E., Knohl Stephen J., Hueber Paul, Hoppe Bernd, Matyus Janos, Simckes Ari, Tasic Velibor, Toenshoff Burkhard, Suchy Sharon F., Nussbaum Robert L., Scheinman Steven J., Dent Disease with Mutations in OCRL1, 10.1086/427887
  30. Hurtado-Lorenzo Andrés, Skinner Mhairi, Annan Jaafar El, Futai Masamitsu, Sun-Wada Ge-Hong, Bourgoin Sylvain, Casanova James, Wildeman Alan, Bechoua Shaliha, Ausiello Dennis A., Brown Dennis, Marshansky Vladimir, V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway, 10.1038/ncb1348
  31. Igarashi Takashi, Fanconi Syndrome, Pediatric Nephrology (2009) ISBN:9783540763277 p.1039-1067, 10.1007/978-3-540-76341-3_42
  32. Iglesias, Am J Physiol Renal Physiol, 277, F711 (1999)
  33. Jentsch Thomas J., Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters : Endosomal CLC chloride transport, 10.1113/jphysiol.2006.124719
  34. Jentsch Thomas J., CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and Physiology, 10.1080/10409230701829110
  35. Jouret F., Bernard A., Hermans C., Dom G., Terryn S., Leal T., Lebecque P., Cassiman J.-J., Scholte B. J., de Jonge H. R., Courtoy P. J., Devuyst O., Cystic Fibrosis Is Associated with a Defect in Apical Receptor-Mediated Endocytosis in Mouse and Human Kidney, 10.1681/asn.2006030269
  36. Jouret François, Devuyst Olivier, CFTR and defective endocytosis: new insights in the renal phenotype of cystic fibrosis, 10.1007/s00424-008-0594-2
  37. Jouret François, Igarashi Takashi, Gofflot Françoise, Wilson Patricia D., Karet Fiona E., Thakker Rajesh V., Devuyst Olivier, Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5, 10.1111/j.1523-1755.2004.00360.x
  38. Kasper Dagmar, Planells-Cases Rosa, Fuhrmann Jens C, Scheel Olaf, Zeitz Oliver, Ruether Klaus, Schmitt Anja, Poët Mallorie, Steinfeld Robert, Schweizer Michaela, Kornak Uwe, Jentsch Thomas J, Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration, 10.1038/sj.emboj.7600576
  39. Kerem B, Rommens J., Buchanan J., Markiewicz D, Cox T., Chakravarti A, Buchwald M, Tsui L., Identification of the cystic fibrosis gene: genetic analysis, 10.1126/science.2570460
  40. Kornak Uwe, Kasper Dagmar, Bösl Michael R, Kaiser Edelgard, Schweizer Michaela, Schulz Ansgar, Friedrich Wilhelm, Delling Günter, Jentsch Thomas J, Loss of the ClC-7 Chloride Channel Leads to Osteopetrosis in Mice and Man, 10.1016/s0092-8674(01)00206-9
  41. Kriz, The Kidney, Physiology and Pathophysiology, 587 (2000)
  42. Lange Philipp F., Wartosch Lena, Jentsch Thomas J., Fuhrmann Jens C., ClC-7 requires Ostm1 as a β-subunit to support bone resorption and lysosomal function, 10.1038/nature04535
  43. Lima W. R., Parreira K. S., Devuyst O., Caplanusi A., N'Kuli F., Marien B., Van Der Smissen P., Alves P. M.S., Verroust P., Christensen E. I., Terzi F., Matter K., Balda M. S., Pierreux C. E., Courtoy P. J., ZONAB Promotes Proliferation and Represses Differentiation of Proximal Tubule Epithelial Cells, 10.1681/asn.2009070698
  44. Lloyd Sarah E., Pearce Simon H. S., Fisher Simon E., Steinmeyer Klaus, Schwappach Blanche, Scheinman Steven J., Harding Brian, Bolino Alessandra, Devoto Marcella, Goodyer Paul, Rigden Susan P. A., Wrong Oliver, Jentsch Thomas J., Craig Ian W., Thakker Rajesh V., A common molecular basis for three inherited kidney stone diseases, 10.1038/379445a0
  45. Lopez-Novoa Jose M., Quiros Yaremi, Vicente Laura, Morales Ana I., Lopez-Hernandez Francisco J., New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view, 10.1038/ki.2010.337
  46. Lourdel Stéphane, Grand Teddy, Burgos Johanna, González Wendy, Sepúlveda Francisco V., Teulon Jacques, ClC-5 mutations associated with Dent’s disease: a major role of the dimer interface, 10.1007/s00424-011-1052-0
  47. Luciani Alessandro, Villella Valeria Rachela, Esposito Speranza, Brunetti-Pierri Nicola, Medina Diego, Settembre Carmine, Gavina Manuela, Pulze Laura, Giardino Ida, Pettoello-Mantovani Massimo, D'Apolito Maria, Guido Stefano, Masliah Eliezer, Spencer Brian, Quaratino Sonia, Raia Valeria, Ballabio Andrea, Maiuri Luigi, Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition, 10.1038/ncb2090
  48. Maritzen T., Rickheit G., Schmitt A., Jentsch T.J., Kidney-specific upregulation of vitamin D3 target genes in ClC-5 KO mice, 10.1038/sj.ki.5000445
  49. Mehta Zenobia B., Pietka Grzegorz, Lowe Martin, The Cellular and Physiological Functions of the Lowe Syndrome Protein OCRL1 : Cellular and Physiological Functions of OCRL1, 10.1111/tra.12160
  50. Mohammad-Panah Raha, Harrison Rene, Dhani Sonja, Ackerley Cameron, Huan Ling-Jun, Wang Yanchun, Bear Christine E., The Chloride Channel ClC-4 Contributes to Endosomal Acidification and Trafficking, 10.1074/jbc.m304357200
  51. Morales, Am J Physiol Renal Physiol, 270, F1038 (1996)
  52. Moreau Kevin, Luo Shouqing, Rubinsztein David C, Cytoprotective roles for autophagy, 10.1016/j.ceb.2009.12.002
  53. Moriyama, J Biol Chem, 262, 9175 (1987)
  54. Moulin Pierre, Igarashi Takashi, Van Der Smissen Patrick, Cosyns Jean-Pierre, Verroust Pierre, Thakker Rajesh V., Scheinman Steven J., Courtoy Pierre J., Devuyst Olivier, Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients, 10.1046/j.1523-1755.2003.00851.x
  55. Nielsen Rikke, Christensen Erik Ilsø, Proteinuria and events beyond the slit, 10.1007/s00467-009-1381-9
  56. Nielsen R., Courtoy P. J., Jacobsen C., Dom G., Lima W. R., Jadot M., Willnow T. E., Devuyst O., Christensen E. I., Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells, 10.1073/pnas.0700330104
  57. Novarino G., Weinert S., Rickheit G., Jentsch T. J., Endosomal Chloride-Proton Exchange Rather Than Chloride Conductance Is Crucial for Renal Endocytosis, 10.1126/science.1188070
  58. O'Connor T.M., McGrath D.S., Short C., O'Donnell M.J., Sheehy M., Bredin C.P., Subclinical anaemia of chronic disease in adult patients with cystic fibrosis, 10.1016/s1569-1993(01)00004-2
  59. Pasyk Eva A., Foskett J. Kevin, Mutant (δF508) Cystic Fibrosis Transmembrane Conductance Regulator Cl−Channel Is Functional When Retained in Endoplasmic Reticulum of Mammalian Cells, 10.1074/jbc.270.21.12347
  60. Picollo Alessandra, Pusch Michael, Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5, 10.1038/nature03720
  61. Piwon Nils, Günther Willy, Schwake Michael, Bösl Michael R., Jentsch Thomas J., ClC-5 Cl--channel disruption impairs endocytosis in a mouse model for Dent's disease, 10.1038/35042597
  62. Plans Vanessa, Rickheit Gesa, Jentsch Thomas J., Physiological roles of CLC Cl−/H+ exchangers in renal proximal tubules, 10.1007/s00424-008-0597-z
  63. Raggi Claudia, Fujiwara Kunio, Leal Teresinha, Jouret François, Devuyst Olivier, Terryn Sara, Decreased renal accumulation of aminoglycoside reflects defective receptor-mediated endocytosis in cystic fibrosis and Dent’s disease, 10.1007/s00424-011-1026-2
  64. Raggi C., Luciani A., Nevo N., Antignac C., Terryn S., Devuyst O., Dedifferentiation and aberrations of the endolysosomal compartment characterize the early stage of nephropathic cystinosis, 10.1093/hmg/ddt617
  65. Reed A. A. C., Loh N. Y., Terryn S., Lippiat J. D., Partridge C., Galvanovskis J., Williams S. E., Jouret F., Wu F. T. F., Courtoy P. J., Nesbit M. A., Rorsman P., Devuyst O., Ashcroft F. M., Thakker R. V., CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease, 10.1152/ajprenal.00038.2009
  66. Rickheit Gesa, Wartosch Lena, Schaffer Sven, Stobrawa Sandra M., Novarino Gaia, Weinert Stefanie, Jentsch Thomas J., Role of ClC-5 in Renal Endocytosis Is Unique among ClC Exchangers and Does Not Require PY-motif-dependent Ubiquitylation, 10.1074/jbc.m110.115600
  67. Riordan, Rommens J., Kerem B, Alon N, Rozmahel R, Grzelczak Z, Zielenski J, Lok S, Plavsic N, Chou J., et al., Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA, 10.1126/science.2475911
  68. Rowe Steven M., Miller Stacey, Sorscher Eric J., Cystic Fibrosis, 10.1056/nejmra043184
  69. Scheel Olaf, Zdebik Anselm A., Lourdel Stéphane, Jentsch Thomas J., Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins, 10.1038/nature03860
  70. Scheinman Steven J., X-linked hypercalciuric nephrolithiasis: Clinical syndromes and chloride channel mutations, 10.1046/j.1523-1755.1998.00718.x
  71. Sheppard, Physiol Rev, 79, S23 (1999)
  72. Shrimpton Antony E., Hoopes, Jr. Richard R., Knohl Stephen J., Hueber Paul, Reed Anita A.C., Christie Paul T., Igarashi Takashi, Lee Philip, Lehman Anna, White Colin, Milford David V., Sanchez Manuel Rivero, Unwin Robert, Wrong Oliver M., Thakker Rajesh V., Scheinman Steven J., OCRL1 Mutations in Dent 2 Patients Suggest a Mechanism for Phenotypic Variability, 10.1159/000213506
  73. Silva Ian V, Cebotaru Valeriu, Wang Hua, Wang Xi-Tao, Wang Sha Sha, Guo Gang, Devuyst Olivier, Thakker Rajesh V, Guggino William B, Guggino Sandra E, The ClC-5 Knockout Mouse Model of Dent's Disease Has Renal Hypercalciuria and Increased Bone Turnover, 10.1359/jbmr.2003.18.4.615
  74. Stauber Tobias, Jentsch Thomas J., Chloride in Vesicular Trafficking and Function, 10.1146/annurev-physiol-030212-183702
  75. Suzuki Tatsunori, Rai Tatemitsu, Hayama Atsushi, Sohara Eisei, Suda Shin, Itoh Tomohiro, Sasaki Sei, Uchida Shinichi, Intracellular localization of ClC chloride channels and their ability to form hetero-oligomers, 10.1002/jcp.20516
  76. Tanaka K., Terryn S., Geffers L., Garbay S., Pontoglio M., Devuyst O., The transcription factor HNF1  regulates expression of chloride-proton exchanger ClC-5 in the renal proximal tubule, 10.1152/ajprenal.00077.2010
  77. Terryn S., Jouret F., Vandenabeele F., Smolders I., Moreels M., Devuyst O., Steels P., Kerkhove E. V., A primary culture of mouse proximal tubular cells, established on collagen-coated membranes, 10.1152/ajprenal.00363.2006
  78. Villella V R, Esposito S, Bruscia E M, Vicinanza M, Cenci S, Guido S, Pettoello-Mantovani M, Carnuccio R, De Matteis M A, Luini A, Maiuri M C, Raia V, Kroemer G, Maiuri L, Disease-relevant proteostasis regulation of cystic fibrosis transmembrane conductance regulator, 10.1038/cdd.2013.46
  79. Wang S. S., Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis, 10.1093/hmg/9.20.2937
  80. Weinert S., Jabs S., Supanchart C., Schweizer M., Gimber N., Richter M., Rademann J., Stauber T., Kornak U., Jentsch T. J., Lysosomal Pathology and Osteopetrosis upon Loss of H+-Driven Lysosomal Cl- Accumulation, 10.1126/science.1188072
  81. Wu Fiona, Reed Anita A.C., Williams Sian E., Loh Nellie Y., Lippiat Jonathan D., Christie Paul T., Large Oliver, Bettinelli Alberto, Dillon Michael J., Goldraich Noemia P., Hoppe Bernd, Lhotta Karl, Loirat Chantal, Malik Rayaz, Morel Delphine, Kotanko Peter, Roussel Bernard, Rubinger Dvora, Schrander-Stumpel Connie, Serdaroglu Erkin, Nesbit M. Andrew, Ashcroft Frances, Thakker Rajesh V., Mutational Analysis of CLC-5, Cofilin and CLC-4 in Patients with Dent’s Disease, 10.1159/000225944
  82. Wu Fiona, Roche Philippe, Christie Paul T., Loh Nellie Y., Reed Anita A.C., Esnouf Robert M., Thakker Rajesh V., Modeling study of human renal chloride channel (hCLC-5) mutations suggests a structural-functional relationship, 10.1046/j.1523-1755.2003.00859.x
  83. Yu W., Beaudry S., Negoro H., Boucher I., Tran M., Kong T., Denker B. M., H2O2 activates G protein,   12 to disrupt the junctional complex and enhance ischemia reperfusion injury, 10.1073/pnas.1116800109
  84. Zhang Xiaoling, Hartz Patricia A., Philip Elizabeth, Racusen Lorraine C., Majerus Philip W., Cell Lines from Kidney Proximal Tubules of a Patient with Lowe Syndrome Lack OCRL Inositol Polyphosphate 5-Phosphatase and Accumulate Phosphatidylinositol 4,5-Bisphosphate, 10.1074/jbc.273.3.1574