User menu

Pharmacological approach to understanding the control of insulin secretion in human islets.

Bibliographic reference Henquin, Jean-Claude ; Dufrane, Denis ; Gmyr, Valery ; Kerr-Conte, Julie ; Nenquin, Myriam. Pharmacological approach to understanding the control of insulin secretion in human islets.. In: Diabetes, obesity & metabolism, Vol. 19, no.8, p. 1061-1070 (2017)
Permanent URL http://hdl.handle.net/2078.1/187503
  1. Henquin J. C., Nenquin M., Ravier M. A., Szollosi A., Shortcomings of current models of glucose-induced insulin secretion, 10.1111/j.1463-1326.2009.01109.x
  2. Straub S. G., James R. F., Dunne M. J., Sharp G. W., Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signaling pathways in human islets, 10.2337/diabetes.47.5.758
  3. Henquin J.-C., Dufrane D., Nenquin M., Nutrient Control of Insulin Secretion in Isolated Normal Human Islets, 10.2337/db06-0868
  4. Ferdaoussi Mourad, Dai Xiaoqing, Jensen Mette V., Wang Runsheng, Peterson Brett S., Huang Chao, Ilkayeva Olga, Smith Nancy, Miller Nathanael, Hajmrle Catherine, Spigelman Aliya F., Wright Robert C., Plummer Gregory, Suzuki Kunimasa, Mackay James P., van de Bunt Martijn, Gloyn Anna L., Ryan Terence E., Norquay Lisa D., Brosnan M. Julia, Trimmer Jeff K., Rolph Timothy P., Kibbey Richard G., Manning Fox Jocelyn E., Colmers William F., Shirihai Orian S., Neufer P. Darrell, Yeh Edward T.H., Newgard Christopher B., MacDonald Patrick E., Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells, 10.1172/jci82498
  5. Amisten Stefan, Salehi Albert, Rorsman Patrik, Jones Peter M., Persaud Shanta J., An atlas and functional analysis of G-protein coupled receptors in human islets of Langerhans, 10.1016/j.pharmthera.2013.05.004
  6. Fridlyand Leonid E., Jacobson David A., Philipson L.H., Ion channels and regulation of insulin secretion in human β-cells : A computational systems analysis, 10.4161/isl.24166
  7. Rorsman Patrik, Braun Matthias, Regulation of Insulin Secretion in Human Pancreatic Islets, 10.1146/annurev-physiol-030212-183754
  8. Henquin Jean-Claude, Dufrane Denis, Kerr-Conte Julie, Nenquin Myriam, Dynamics of glucose-induced insulin secretion in normal human islets, 10.1152/ajpendo.00251.2015
  9. Dufrane Denis, Goebbels Rose-Marie, Guiot Yves, Squifflet Jean-Paul, Henquin Jean-Claude, Gianello Pierre, A Simple Method Using a Polymethylpenten Chamber for Isolation of Human Pancreatic Islets : , 10.1097/01.mpa.0000157584.22880.f6
  10. Kerr-Conte Julie, Vandewalle Brigitte, Moerman Ericka, Lukowiak Bruno, Gmyr Valery, Arnalsteen Laurent, Caiazzo Robert, Sterkers Adrien, Hubert Thomas, Vantyghem Marie Christine, Pattou François, Upgrading Pretransplant Human Islet Culture Technology Requires Human Serum Combined With Media Renewal : , 10.1097/tp.0b013e3181d154ac
  11. Bedoya F. J., Wilson J. M., Ghosh A. K., Finegold D., Matschinsky F. M., The Glucokinase Glucose Sensor in Human Pancreatic Islet Tissue, 10.2337/diab.35.1.61
  12. De Vos A, Heimberg H, Quartier E, Huypens P, Bouwens L, Pipeleers D, Schuit F, Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression., 10.1172/jci118308
  13. Grimsby J., Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy, 10.1126/science.1084073
  14. Johnson D., Shepherd R. M., Gill D., Gorman T., Smith D. M., Dunne M. J., Glucose-Dependent Modulation of Insulin Secretion and Intracellular Calcium Ions by GKA50, a Glucokinase Activator, 10.2337/db07-0026
  15. Doliba N. M., Qin W., Najafi H., Liu C., Buettger C. W., Sotiris J., Collins H. W., Li C., Stanley C. A., Wilson D. F., Grimsby J., Sarabu R., Naji A., Matschinsky F. M., Glucokinase activation repairs defective bioenergetics of islets of Langerhans isolated from type 2 diabetics, 10.1152/ajpendo.00218.2011
  16. Henquin J.-C., Sempoux C., Marchandise J., Godecharles S., Guiot Y., Nenquin M., Rahier J., Congenital Hyperinsulinism Caused by Hexokinase I Expression or Glucokinase-Activating Mutation in a Subset of  -Cells, 10.2337/db12-1414
  17. Martin Franz, Soria Bernat, Glucoseminduced [Ca2+]i oscillations in single human pancreatic islets, 10.1016/s0143-4160(96)90003-2
  18. Shibasaki T., Takahashi T., Takahashi H., Seino S., Cooperation between cAMP signalling and sulfonylurea in insulin secretion, 10.1111/dom.12343
  19. Nenquin M., Henquin J.-C., Sulphonylurea receptor-1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells, 10.1111/dom.12607
  20. Li Changhong, Buettger Carol, Kwagh Jae, Matter Andrea, Daikhin Yevgeny, Nissim Ilana B., Collins Heather W., Yudkoff Marc, Stanley Charles A., Matschinsky Franz M., A Signaling Role of Glutamine in Insulin Secretion, 10.1074/jbc.m311502200
  21. Liu Yi-Jia, Cheng Haiying, Drought Heather, MacDonald Michael J., Sharp Geoffrey W. G., Straub Susanne G., Activation of the KATPchannel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH, 10.1152/ajpendo.00008.2003
  22. Misler S., Barnett D. W., Pressel D. M., Gillis K. D., Scharp D. W., Falke L. C., Stimulus-Secretion Coupling in  -Cells of Transplantable Human Islets of Langerhans: Evidence for a Critical Role for Ca2+ Entry, 10.2337/diab.41.6.662
  23. Rojas E, Carroll P B, Ricordi C, Boschero A C, Stojilkovic S S, Atwater I, Control of cytosolic free calcium in cultured human pancreatic beta-cells occurs by external calcium-dependent and independent mechanisms., 10.1210/endo.134.4.8137742
  24. Mourad N. I., Nenquin M., Henquin J.-C., Metabolic amplifying pathway increases both phases of insulin secretion independently of  -cell actin microfilaments, 10.1152/ajpcell.00138.2010
  25. Misler S., Gee W. M., Gillis K. D., Scharp D. W., Falke L. C., Metabolite-Regulated ATP-Sensitive K+ Channel in Human Pancreatic Islet Cells, 10.2337/diab.38.4.422
  26. Herrington James, Sanchez Manuel, Wunderler Denize, Yan Lizhen, Bugianesi Randal M., Dick Ivy E., Clark Sam A., Brochu Richard M., Priest Birgit T., Kohler Martin G., McManus Owen B., Biophysical and pharmacological properties of the voltage-gated potassium current of human pancreatic β-cells : Kv currents of human pancreatic β-cells, 10.1113/jphysiol.2005.089375
  27. Braun M., Ramracheya R., Bengtsson M., Zhang Q., Karanauskaite J., Partridge C., Johnson P. R., Rorsman P., Voltage-Gated Ion Channels in Human Pancreatic  -Cells: Electrophysiological Characterization and Role in Insulin Secretion, 10.2337/db07-0991
  28. Henquin Jean -Claude, Role of voltage- and Ca2+-dependent K+ channels in the control of glucose-induced electrical activity in pancreatic B-cells, 10.1007/bf00382691
  29. Li X., Herrington J., Petrov A., Ge L., Eiermann G., Xiong Y., Jensen M. V., Hohmeier H. E., Newgard C. B., Garcia M. L., Wagner M., Zhang B. B., Thornberry N. A., Howard A. D., Kaczorowski G. J., Zhou Y.-P., The Role of Voltage-Gated Potassium Channels Kv2.1 and Kv2.2 in the Regulation of Insulin and Somatostatin Release from Pancreatic Islets, 10.1124/jpet.112.199083
  30. Dadi Prasanna K., Vierra Nicholas C., Jacobson David A., Pancreatic β-Cell–specific Ablation of TASK-1 Channels Augments Glucose-stimulated Calcium Entry and Insulin Secretion, Improving Glucose Tolerance, 10.1210/en.2013-2051
  31. Tamarina N. A., Wang Y., Mariotto L., Kuznetsov A., Bond C., Adelman J., Philipson L. H., Small-Conductance Calcium-Activated K+ Channels Are Expressed in Pancreatic Islets and Regulate Glucose Responses, 10.2337/diabetes.52.8.2000
  32. Zhang Min, Houamed Khaled, Kupershmidt Sabina, Roden Dan, Satin Leslie S., Pharmacological Properties and Functional Role of KslowCurrent in Mouse Pancreatic β-Cells : SK Channels Contribute to KslowTail Current and Modulate Insulin Secretion, 10.1085/jgp.200509312
  33. Dufer M., Gier B., Wolpers D., Krippeit-Drews P., Ruth P., Drews G., Enhanced Glucose Tolerance by SK4 Channel Inhibition in Pancreatic  -Cells, 10.2337/db08-1324
  34. Jacobson David A., Mendez Felipe, Thompson Michael, Torres Jacqueline, Cochet Olivia, Philipson Louis H., Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses : Kv and KCaregulation of islet electrical activity, 10.1113/jphysiol.2010.190207
  35. Riz Michela, Braun Matthias, Pedersen Morten Gram, Mathematical Modeling of Heterogeneous Electrophysiological Responses in Human β-Cells, 10.1371/journal.pcbi.1003389
  36. Henquin J. C., Charles S., Nenquin M., Mathot F., Tamagawa T., Diazoxide and D600 Inhibition of Insulin Release: Distinct Mechanisms Explain the Specificity for Different Stimuli, 10.2337/diab.31.9.776
  37. Davalli A M, Biancardi E, Pollo A, Socci C, Pontiroli A E, Pozza G, Clementi F, Sher E, Carbone E, Dihydropyridine-sensitive and -insensitive voltage-operated calcium channels participate in the control of glucose-induced insulin release from human pancreatic   cells, 10.1677/joe.0.1500195
  38. Donatsch P., Lowe D. A., Richardson B. P., Taylor Pamela, The functional significance of sodium channels in pancreatic beta-cell membranes, 10.1113/jphysiol.1977.sp011817
  39. Pace, Am J Physiol, 237, E130 (1979)
  40. MacDonald Patrick E, Marinis Yang Zhang De, Ramracheya Reshma, Salehi Albert, Ma Xiaosong, Johnson Paul R. V, Cox Roger, Eliasson Lena, Rorsman Patrik, A KATP Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans, 10.1371/journal.pbio.0050143
  41. Plant T. D., Na+ currents in cultured mouse pancreatic B-cells, 10.1007/bf00587723
  42. Barnett David W., Pressel David M., Misler Stanley, Voltage-dependent Na+ and Ca2+ currents in human pancreatic islet ?-cells: evidence for roles in the generation of action potentials and insulin secretion, 10.1007/bf00410201
  43. Grespan, Diabetologia, 59, S261 (2016)
  44. MacDonald Michael J., Longacre Melissa J., Stoker Scott W., Kendrick Mindy, Thonpho Ansaya, Brown Laura J., Hasan Noaman M., Jitrapakdee Sarawut, Fukao Toshiyuki, Hanson Matthew S., Fernandez Luis A., Odorico Jon, Differences between Human and Rodent Pancreatic Islets : LOW PYRUVATE CARBOXYLASE, ATP CITRATE LYASE, AND PYRUVATE CARBOXYLATION AND HIGH GLUCOSE-STIMULATED ACETOACETATE IN HUMAN PANCREATIC ISLETS, 10.1074/jbc.m111.241182