User menu

N-Glycosylation of an IgG antibody secreted by Nicotiana tabacum BY-2 cells can be modulated through co-expression of human β-1,4-galactosyltransferase

Bibliographic reference Navarre, Catherine ; Smargiasso, Nicolas ; Duvivier, Laurent ; Nader, Joseph ; Far, Johann ; et. al. N-Glycosylation of an IgG antibody secreted by Nicotiana tabacum BY-2 cells can be modulated through co-expression of human β-1,4-galactosyltransferase. In: Transgenic Research, Vol. 26, no.3, p. 375-384 (2017)
Permanent URL
  1. Bakker H., Bardor M., Molthoff J. W., Gomord V., Elbers I., Stevens L. H., Jordi W., Lommen A., Faye L., Lerouge P., Bosch D., Galactose-extended glycans of antibodies produced by transgenic plants, 10.1073/pnas.031419998
  2. Bakker H., Rouwendal G. J. A., Karnoup A. S., Florack D. E. A., Stoopen G. M., Helsper J. P. F. G., van Ree R., van Die I., Bosch D., An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes, 10.1073/pnas.0600879103
  3. Bosch Dirk, Castilho Alexandra, Loos Andreas, Schots Arjen, Steinkellner Herta, N-Glycosylation of Plant-produced Recombinant Proteins, 10.2174/1381612811319310006
  4. Bradford Marion M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, 10.1016/0003-2697(76)90527-3
  5. Brandizzi F., Membrane Protein Transport between the Endoplasmic Reticulum and the Golgi in Tobacco Leaves Is Energy Dependent but Cytoskeleton Independent: Evidence from Selective Photobleaching, 10.1105/tpc.001586
  6. Fujiyama Kazuhito, Misaki Ryo, Katsura Atsuya, Tanaka Tomoko, Furukawa Aiko, Omasa Takeshi, Seki Tatsuji, N-linked glycan structures of a mouse monoclonal antibody produced from tobacco BY2 suspension-cultured cells, 10.1263/jbb.101.212
  7. Fujiyama Kazuhito, Furukawa Aiko, Katsura Atsuya, Misaki Ryo, Omasa Takeshi, Seki Tatsuji, Production of mouse monoclonal antibody with galactose-extended sugar chain by suspension cultured tobacco BY2 cells expressing human β(1,4)-galactosyltransferase, 10.1016/j.bbrc.2007.04.054
  8. Goderis Inge J.W.M., De Bolle Miguel F.C., François Isabelle E.J.A., Wouters Piet F.J., Broekaert Willem F., Cammue Bruno P.A., 10.1023/a:1016052416053
  9. Hesselink Thamara, Rouwendal Gerard J. A., Henquet Maurice G. L., Florack Dion E. A., Helsper Johannes P. F. G., Bosch Dirk, Expression of natural human β1,4-GalT1 variants and of non-mammalian homologues in plants leads to differences in galactosylation of N-glycans, 10.1007/s11248-014-9806-z
  10. Holland T., Sack M., Rademacher T., Schmale K., Altmann F., Stadlmann J., Fischer R., Hellwig S., Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full-size antibody in BY-2 suspension culture, 10.1002/bit.22800
  11. Jacobs P., Callewaert N., N-glycosylation Engineering of Biopharmaceutical Expression Systems, 10.2174/156652409789105552
  12. Kajiura Hiroyuki, Misaki Ryo, Fujiyama Kazuhito, Seki Tatsuji, Stable coexpression of two human sialylation enzymes in plant suspension-cultured tobacco cells, 10.1016/j.jbiosc.2010.11.018
  13. Kallolimath Somanath, Steinkellner Herta, Glycosylation of plant produced human antibodies, 10.3233/hab-150283
  14. Kang Seung Hoon, Jung Hahn Sun, Lee Song Jae, Park Cheon Ik, Lim Sang Min, Park Heajin, Kim Byung Sun, Na Kwang Heum, Han Gyeong Jin, Bae Jae Woo, Park Hyun Joo, Bang Keuk Chan, Park Byung Tae, Hwang Hye Seong, Jung In-Soo, Kim Jae Il, Oh Doo Byung, Kim Dong Il, Yagi Hirokazu, Kato Koichi, Kim Dae Kyong, Kim Ha Hyung, Glycan structure and serum half-life of recombinant CTLA4Ig, an immunosuppressive agent, expressed in suspension-cultured rice cells with coexpression of human β1,4-galactosyltransferase and human CTLA4Ig, 10.1007/s10719-015-9590-x
  15. Karg Saskia R., Frey Alexander D., Kallio Pauli T., Reduction of N-linked xylose and fucose by expression of rat β1,4-N-acetylglucosaminyltransferase III in tobacco BY-2 cells depends on Golgi enzyme localization domain and genetic elements used for expression, 10.1016/j.jbiotec.2010.01.005
  16. Loos Andreas, Steinkellner Herta, IgG-Fc glycoengineering in non-mammalian expression hosts, 10.1016/
  17. Magy Bertrand, Tollet Jérémie, Laterre Raphaëlle, Boutry Marc, Navarre Catherine, Accumulation of secreted antibodies in plant cell cultures varies according to the isotype, host species and culture conditions, 10.1111/pbi.12152
  18. Mercx Sébastien, Tollet Jérémie, Magy Bertrand, Navarre Catherine, Boutry Marc, Gene Inactivation by CRISPR-Cas9 in Nicotiana tabacum BY-2 Suspension Cells, 10.3389/fpls.2016.00040
  19. MISAKI Ryo, KIMURA Yoshinobu, FUJIYAMA Kazuhito, SEKI Tatsuji, Glycoproteins Secreted from Suspension-cultured Tobacco BY2 Cells have Distinct Glycan Structures from Intracellular Glycoproteins, 10.1271/bbb.65.2482
  20. Misaki R., Plant cultured cells expressing human beta1,4-galactosyltransferase secrete glycoproteins with galactose-extended N-linked glycans, 10.1093/glycob/cwg021
  21. Misaki Ryo, Fujiyama Kazuhito, Seki Tatsuji, Expression of human CMP-N-acetylneuraminic acid synthetase and CMP-sialic acid transporter in tobacco suspension-cultured cell, 10.1016/j.bbrc.2005.11.130
  22. Morsomme Pierre, Dambly Stéphanie, Maudoux Olivier, Boutry Marc, Single Point Mutations Distributed in 10 Soluble and Membrane Regions of theNicotiana plumbaginifoliaPlasma Membrane PMA2 H+-ATPase Activate the Enzyme and Modify the Structure of the C-terminal Region, 10.1074/jbc.273.52.34837
  23. Navarre Catherine, Delannoy Mélanie, Lefebvre Benoit, Nader Joseph, Vanham Delphine, Boutry Marc, Expression and Secretion of Recombinant Outer-surface Protein A from the Lyme Disease Agent, Borrelia burgdorferi, in Nicotiana tabacum Suspension Cells, 10.1007/s11248-006-0002-7
  24. Palacpac N. Q., Yoshida S., Sakai H., Kimura Y., Fujiyama K., Yoshida T., Seki T., Stable expression of human  1,4-galactosyltransferase in plant cells modifies N-linked glycosylation patterns, 10.1073/pnas.96.8.4692
  25. Raven Nicole, Rasche Stefan, Kuehn Christoph, Anderlei Tibor, Klöckner Wolf, Schuster Flora, Henquet Maurice, Bosch Dirk, Büchs Jochen, Fischer Rainer, Schillberg Stefan, Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor : Scaled-up Antibody Production in Plant Cells, 10.1002/bit.25352
  26. Reusch Dietmar, Tejada Max L, Fc glycans of therapeutic antibodies as critical quality attributes, 10.1093/glycob/cwv065
  27. Saint-Jore Claude M., Evins Janet, Batoko Henri, Brandizzi Federica, Moore Ian, Hawes Chris, Redistribution of membrane proteins between the Golgi apparatus and endoplasmic reticulum in plants is reversible and not dependent on cytoskeletal networks, 10.1046/j.0960-7412.2002.01252.x
  28. Santos Rita B., Abranches Rita, Fischer Rainer, Sack Markus, Holland Tanja, Putting the Spotlight Back on Plant Suspension Cultures, 10.3389/fpls.2016.00297
  29. Schneider Jeannine, Castilho Alexandra, Pabst Martin, Altmann Friedrich, Gruber Clemens, Strasser Richard, Gattinger Pia, Seifert Georg J., Steinkellner Herta, Characterization of plants expressing the human β1,4-galactosyltrasferase gene, 10.1016/j.plaphy.2015.04.010
  30. Schoberer Jennifer, Strasser Richard, Sub-Compartmental Organization of Golgi-Resident N-Glycan Processing Enzymes in Plants, 10.1093/mp/ssq082
  31. Schoberer J., Liebminger E., Botchway S. W., Strasser R., Hawes C., Time-Resolved Fluorescence Imaging Reveals Differential Interactions of N-Glycan Processing Enzymes across the Golgi Stack in Planta, 10.1104/pp.112.210757
  32. Schoberer Jennifer, Liebminger Eva, Vavra Ulrike, Veit Christiane, Castilho Alexandra, Dicker Martina, Maresch Daniel, Altmann Friedrich, Hawes Chris, Botchway Stanley W., Strasser Richard, The transmembrane domain ofN -acetylglucosaminyltransferase I is the key determinant for its Golgi subcompartmentation, 10.1111/tpj.12671
  33. Strasser Richard, Plant protein glycosylation, 10.1093/glycob/cww023
  34. Strasser Richard, Castilho Alexandra, Stadlmann Johannes, Kunert Renate, Quendler Heribert, Gattinger Pia, Jez Jakub, Rademacher Thomas, Altmann Friedrich, Mach Lukas, Steinkellner Herta, Improved Virus Neutralization by Plant-produced Anti-HIV Antibodies with a Homogeneous β1,4-GalactosylatedN-Glycan Profile, 10.1074/jbc.m109.014126
  35. Strasser Richard, Altmann Friedrich, Steinkellner Herta, Controlled glycosylation of plant-produced recombinant proteins, 10.1016/j.copbio.2014.06.008
  36. van der Fits Leslie, Deakin Edward A., Hoge J. Harry C., Memelink Johan, 10.1023/a:1006440221718
  37. Vézina Louis-P., Faye Loïc, Lerouge Patrice, D’Aoust Marc-André, Marquet-Blouin Estelle, Burel Carole, Lavoie Pierre-Olivier, Bardor Muriel, Gomord Véronique, Transient co-expression for fast and high-yield production of antibodies with human-likeN-glycans in plants, 10.1111/j.1467-7652.2009.00414.x
  38. Yin Bo-jiao, Gao Ting, Zheng Nuo-yan, Li Yin, Tang San-yuan, Liang Li-ming, Xie Qi, Generation of glyco-engineered BY2 cell lines with decreased expression of plant-specific glycoepitopes, 10.1007/s13238-011-1007-4