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IL-22BP is produced by eosinophils in human gut and blocks IL-22 protective actions during colitis.

Bibliographic reference Martin, J C ; Bériou, G ; Heslan, M ; Bossard, C ; Jarry, A ; et. al. IL-22BP is produced by eosinophils in human gut and blocks IL-22 protective actions during colitis.. In: Mucosal Immunology, Vol. 9, no.2, p. 539-549 (2015)
Permanent URL http://hdl.handle.net/2078.1/184353
  1. Kaser Arthur, Zeissig Sebastian, Blumberg Richard S., Inflammatory Bowel Disease, 10.1146/annurev-immunol-030409-101225
  2. Sabat Robert, Ouyang Wenjun, Wolk Kerstin, Therapeutic opportunities of the IL-22–IL-22R1 system, 10.1038/nrd4176
  3. Andoh Akira, Zhang Zhuobin, Inatomi Osamu, Fujino Sanae, Deguchi Yasuyuki, Araki Yoshio, Tsujikawa Tomoyuki, Kitoh Katsuyuki, Kim–Mitsuyama Shokei, Takayanagi Atsushi, Shimizu Nobuyoshi, Fujiyama Yoshihide, Interleukin-22, a Member of the IL-10 Subfamily, Induces Inflammatory Responses in Colonic Subepithelial Myofibroblasts, 10.1053/j.gastro.2005.06.071
  4. Brand S., IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration, 10.1152/ajpgi.00513.2005
  5. Schmechel Silke, Konrad Astrid, Diegelmann Julia, Glas Jürgen, Wetzke Martin, Paschos Ekaterini, Lohse Peter, Göke Burkhard, Brand Stephan, Linking genetic susceptibility to Crohnʼs disease with Th17 cell function: IL-22 serum levels are increased in Crohnʼs disease and correlate with disease activity and IL23R genotype status : , 10.1002/ibd.20315
  6. Sugimoto K., J Clin Invest, 118, 534 (2008)
  7. Pariente Benjamin, Mocan Iulia, Camus Matthieu, Dutertre Charles–Antoine, Ettersperger Julien, Cattan Pierre, Gornet Jean–Marc, Dulphy Nicolas, Charron Dominique, Lémann Marc, Toubert Antoine, Allez Matthieu, Activation of the Receptor NKG2D Leads to Production of Th17 Cytokines in CD4+ T Cells of Patients With Crohn's Disease, 10.1053/j.gastro.2011.03.061
  8. Geremia Alessandra, Arancibia-Cárcamo Carolina V., Fleming Myles P.P., Rust Nigel, Singh Baljit, Mortensen Neil J., Travis Simon P.L., Powrie Fiona, IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease, 10.1084/jem.20101712
  9. Zenewicz Lauren A., Yancopoulos George D., Valenzuela David M., Murphy Andrew J., Stevens Sean, Flavell Richard A., Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease, 10.1016/j.immuni.2008.11.003
  10. Pickert Geethanjali, Neufert Clemens, Leppkes Moritz, Zheng Yan, Wittkopf Nadine, Warntjen Moritz, Lehr Hans-Anton, Hirth Sebastian, Weigmann Benno, Wirtz Stefan, Ouyang Wenjun, Neurath Markus F., Becker Christoph, STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing, 10.1084/jem.20082683
  11. Monteleone Ivan, Rizzo Angelamaria, Sarra Massimiliano, Sica Giuseppe, Sileri Pierpaolo, Biancone Livia, MacDonald Thomas T., Pallone Francesco, Monteleone Giovanni, Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract, 10.1053/j.gastro.2011.04.007
  12. Zindl C. L., Lai J.-F., Lee Y. K., Maynard C. L., Harbour S. N., Ouyang W., Chaplin D. D., Weaver C. T., IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis, 10.1073/pnas.1300318110
  13. Mielke Lisa A., Jones Sarah A., Raverdeau Mathilde, Higgs Rowan, Stefanska Anna, Groom Joanna R., Misiak Alicja, Dungan Lara S., Sutton Caroline E., Streubel Gundula, Bracken Adrian P., Mills Kingston H.G., Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation, 10.1084/jem.20121588
  14. Xu W., Presnell S. R., Parrish-Novak J., Kindsvogel W., Jaspers S., Chen Z., Dillon S. R., Gao Z., Gilbert T., Madden K., Schlutsmeyer S., Yao L., Whitmore T. E., Chandrasekher Y., Grant F. J., Maurer M., Jelinek L., Storey H., Brender T., Hammond A., Topouzis S., Clegg C. H., Foster D. C., A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist, 10.1073/pnas.171303198
  15. Logsdon Naomi J., Jones Brandi C., Josephson Kristopher, Cook Jennifer, Walter Mark R., Comparison of Interleukin-22 and Interleukin-10 Soluble Receptor Complexes, 10.1089/10799900260442520
  16. Huber Samuel, Gagliani Nicola, Zenewicz Lauren A., Huber Francis J., Bosurgi Lidia, Hu Bo, Hedl Matija, Zhang Wei, O’Connor William, Murphy Andrew J., Valenzuela David M., Yancopoulos George D., Booth Carmen J., Cho Judy H., Ouyang Wenjun, Abraham Clara, Flavell Richard A., IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine, 10.1038/nature11535
  17. Martin J CJ, Bériou G, Heslan M, Chauvin C, Utriainen L, Aumeunier A, Scott C L, Mowat A, Cerovic V, Houston S A, Leboeuf M, Hubert F X, Hémont C, Merad M, Milling S, Josien R, Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid, 10.1038/mi.2013.28
  18. Watchmaker Payal B, Lahl Katharina, Lee Mike, Baumjohann Dirk, Morton John, Kim Sun Jung, Zeng Ruizhu, Dent Alexander, Ansel K Mark, Diamond Betty, Hadeiba Husein, Butcher Eugene C, Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice, 10.1038/ni.2768
  19. Jung Y., Rothenberg M. E., Roles and Regulation of Gastrointestinal Eosinophils in Immunity and Disease, 10.4049/jimmunol.1400413
  20. Dumoutier L., Lejeune D., Colau D., Renauld J.-C., Cloning and Characterization of IL-22 Binding Protein, a Natural Antagonist of IL-10-Related T Cell-Derived Inducible Factor/IL-22, 10.4049/jimmunol.166.12.7090
  21. Hogan Simon P., Waddell Amanda, Fulkerson Patricia C., Eosinophils in infection and intestinal immunity : , 10.1097/mog.0b013e32835ab29a
  22. Gaudio Eugenio, 10.1023/a:1026620322859
  23. Zenewicz L. A., Yin X., Wang G., Elinav E., Hao L., Zhao L., Flavell R. A., IL-22 Deficiency Alters Colonic Microbiota To Be Transmissible and Colitogenic, 10.4049/jimmunol.1300016
  24. Sonnenberg G. F., Monticelli L. A., Alenghat T., Fung T. C., Hutnick N. A., Kunisawa J., Shibata N., Grunberg S., Sinha R., Zahm A. M., Tardif M. R., Sathaliyawala T., Kubota M., Farber D. L., Collman R. G., Shaked A., Fouser L. A., Weiner D. B., Tessier P. A., Friedman J. R., Kiyono H., Bushman F. D., Chang K.-M., Artis D., Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria, 10.1126/science.1222551
  25. Kleinschek Melanie A., Boniface Katia, Sadekova Svetlana, Grein Jeff, Murphy Erin E., Turner Scott P., Raskin Lisa, Desai Bela, Faubion William A., de Waal Malefyt Rene, Pierce Robert H., McClanahan Terrill, Kastelein Robert A., Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation, 10.1084/jem.20081712
  26. Ramesh Radha, Kozhaya Lina, McKevitt Kelly, Djuretic Ivana M., Carlson Thaddeus J., Quintero Maria A., McCauley Jacob L., Abreu Maria T., Unutmaz Derya, Sundrud Mark S., Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids, 10.1084/jem.20130301
  27. Longman Randy S., Diehl Gretchen E., Victorio Daniel A., Huh Jun R., Galan Carolina, Miraldi Emily R., Swaminath Arun, Bonneau Richard, Scherl Ellen J., Littman Dan R., CX3CR1+mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22, 10.1084/jem.20140678
  28. Kamada N., J. Clin. Invest., 118, 2269 (2008)
  29. Begue Bernadette, Verdier Julien, Rieux-Laucat Frédéric, Goulet Olivier, Morali Alain, Canioni Danielle, Hugot Jean-Pierre, Daussy Cécile, Verkarre Virginie, Pigneur Bénédicte, Fischer Alain, Klein Christoph, Cerf-Bensussan Nadine, Ruemmele Frank M, Defective IL10 Signaling Defining a Subgroup of Patients With Inflammatory Bowel Disease, 10.1038/ajg.2011.112
  30. Nakajima T., Gene expression screening of human mast cells and eosinophils using high-density oligonucleotide probe arrays: abundant expression of major basic protein in mast cells, 10.1182/blood.v98.4.1127
  31. Macpherson A J, McCoy K D, Standardised animal models of host microbial mutualism, 10.1038/mi.2014.113
  32. Ivanov Ivaylo I., Atarashi Koji, Manel Nicolas, Brodie Eoin L., Shima Tatsuichiro, Karaoz Ulas, Wei Dongguang, Goldfarb Katherine C., Santee Clark A., Lynch Susan V., Tanoue Takeshi, Imaoka Akemi, Itoh Kikuji, Takeda Kiyoshi, Umesaki Yoshinori, Honda Kenya, Littman Dan R., Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria, 10.1016/j.cell.2009.09.033
  33. Gaboriau-Routhiau Valérie, Rakotobe Sabine, Lécuyer Emelyne, Mulder Imke, Lan Annaïg, Bridonneau Chantal, Rochet Violaine, Pisi Annamaria, De Paepe Marianne, Brandi Giovanni, Eberl Gérard, Snel Johannes, Kelly Denise, Cerf-Bensussan Nadine, The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses, 10.1016/j.immuni.2009.08.020
  34. Spencer S. P., Wilhelm C., Yang Q., Hall J. A., Bouladoux N., Boyd A., Nutman T. B., Urban J. F., Wang J., Ramalingam T. R., Bhandoola A., Wynn T. A., Belkaid Y., Adaptation of Innate Lymphoid Cells to a Micronutrient Deficiency Promotes Type 2 Barrier Immunity, 10.1126/science.1247606
  35. Ueki S., Nishikawa J., Yamauchi Y., Konno Y., Tamaki M., Itoga M., Kobayashi Y., Takeda M., Moritoki Y., Ito W., Chihara J., Retinoic acids up-regulate functional eosinophil-driving receptor CCR3, 10.1111/all.12175
  36. Lee James J., Jacobsen Elizabeth A., Ochkur Sergei I., McGarry Michael P., Condjella Rachel M., Doyle Alfred D., Luo Huijun, Zellner Katie R., Protheroe Cheryl A., Willetts Lian, LeSuer William E., Colbert Dana C., Helmers Richard A., Lacy Paige, Moqbel Redwan, Lee Nancy A., Human versus mouse eosinophils: “That which we call an eosinophil, by any other name would stain as red”, 10.1016/j.jaci.2012.07.025
  37. Chu Van Trung, Beller Alexander, Rausch Sebastian, Strandmark Julia, Zänker Michael, Arbach Olga, Kruglov Andrey, Berek Claudia, Eosinophils Promote Generation and Maintenance of Immunoglobulin-A-Expressing Plasma Cells and Contribute to Gut Immune Homeostasis, 10.1016/j.immuni.2014.02.014
  38. Goto Yoshiyuki, Panea Casandra, Nakato Gaku, Cebula Anna, Lee Carolyn, Diez Marta Galan, Laufer Terri M., Ignatowicz Leszek, Ivanov Ivaylo I., Segmented Filamentous Bacteria Antigens Presented by Intestinal Dendritic Cells Drive Mucosal Th17 Cell Differentiation, 10.1016/j.immuni.2014.03.005
  39. Kamada Nobuhiko, Seo Sang-Uk, Chen Grace Y., Núñez Gabriel, Role of the gut microbiota in immunity and inflammatory disease, 10.1038/nri3430
  40. Kryczek Ilona, Lin Yanwei, Nagarsheth Nisha, Peng Dongjun, Zhao Lili, Zhao Ende, Vatan Linda, Szeliga Wojciech, Dou Yali, Owens Scott, Zgodzinski Witold, Majewski Marek, Wallner Grzegorz, Fang Jingyuan, Huang Emina, Zou Weiping, IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L, 10.1016/j.immuni.2014.03.010
  41. Kamanaka Masahito, Huber Samuel, Zenewicz Lauren A., Gagliani Nicola, Rathinam Chozhavendan, O'Connor William, Wan Yisong Y., Nakae Susumu, Iwakura Yoichiro, Hao Liming, Flavell Richard A., Memory/effector (CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22–dependent intestinal pathology, 10.1084/jem.20102149
  42. Eken A, Singh A K, Treuting P M, Oukka M, IL-23R+ innate lymphoid cells induce colitis via interleukin-22-dependent mechanism, 10.1038/mi.2013.33
  43. Vonarbourg Cedric, Mortha Arthur, Bui Viet L., Hernandez Pedro P., Kiss Elina A., Hoyler Thomas, Flach Melanie, Bengsch Bertram, Thimme Robert, Hölscher Christoph, Hönig Manfred, Pannicke Ulrich, Schwarz Klaus, Ware Carl F., Finke Daniela, Diefenbach Andreas, Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt+ Innate Lymphocytes, 10.1016/j.immuni.2010.10.017
  44. Zheng Yan, Valdez Patricia A, Danilenko Dimitry M, Hu Yan, Sa Susan M, Gong Qian, Abbas Alexander R, Modrusan Zora, Ghilardi Nico, de Sauvage Frederic J, Ouyang Wenjun, Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens, 10.1038/nm1720
  45. Moriwaki Kenta, Balaji Sakthi, McQuade Thomas, Malhotra Nidhi, Kang Joonsoo, Chan Francis Ka-Ming, The Necroptosis Adaptor RIPK3 Promotes Injury-Induced Cytokine Expression and Tissue Repair, 10.1016/j.immuni.2014.09.016
  46. Zelante Teresa, Iannitti Rossana G., Cunha Cristina, De Luca Antonella, Giovannini Gloria, Pieraccini Giuseppe, Zecchi Riccardo, D’Angelo Carmen, Massi-Benedetti Cristina, Fallarino Francesca, Carvalho Agostinho, Puccetti Paolo, Romani Luigina, Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22, 10.1016/j.immuni.2013.08.003
  47. Geurts A. M., Cost G. J., Freyvert Y., Zeitler B., Miller J. C., Choi V. M., Jenkins S. S., Wood A., Cui X., Meng X., Vincent A., Lam S., Michalkiewicz M., Schilling R., Foeckler J., Kalloway S., Weiler H., Menoret S., Anegon I., Davis G. D., Zhang L., Rebar E. J., Gregory P. D., Urnov F. D., Jacob H. J., Buelow R., Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases, 10.1126/science.1172447
  48. Jarry A., J. Clin. Invest., 118, 1132 (2008)