User menu

CD8 T-cell responses against the immunodominantTheileria parvapeptide Tp249-59are composed of two distinct populations specific for overlapping 11-mer and 10-mer epitopes

Bibliographic reference Connelley, Timothy K. ; Li, Xiaoying ; MacHugh, Niall ; Colau, Didier ; Graham, Simon P. ; et. al. CD8 T-cell responses against the immunodominantTheileria parvapeptide Tp249-59are composed of two distinct populations specific for overlapping 11-mer and 10-mer epitopes. In: Immunology : the journal of cells, molecules, system and technologies, Vol. 149, no.2, p. 172-185 (2016)
Permanent URL
  1. Radley D.E., Brown C.G.D., Burridge M.J., Cunningham M.P., Kirimi I.M., Purnell R.E., Young A.S., East coast fever: 1. Chemoprophylactic immunization of cattle against Theileria parva (Muguga) and five theilerial strains, 10.1016/0304-4017(75)90005-9
  2. Goddeeris Bruno M., Ivan Morrison W., Teale Alan J., Generation of bovine cytotoxic cell lines, specific for cells infected with the protozoan parasiteTheileria parva and restricted by products of the major histocompatibility complex, 10.1002/eji.1830161010
  3. Goddeeris, Immunology, 69, 38 (1990)
  4. McKeever D. J., Taracha E. L., Innes E. L., MacHugh N. D., Awino E., Goddeeris B. M., Morrison W. I., Adoptive transfer of immunity to Theileria parva in the CD8+ fraction of responding efferent lymph., 10.1073/pnas.91.5.1959
  5. MORRISON W. I., GODDEERIS B. M., TEALE A. J., GROOCOCK C. M., KEMP S. J., STAGG D. A., Cytotoxic T-cells elicited in cattle challenged with Theileria parva (Muguga): evidence for restriction by class I MHC determinants and parasite strain specificity, 10.1111/j.1365-3024.1987.tb00530.x
  6. Taracha, Infect Immun, 63, 1258 (1995)
  7. Graham S. P., Pelle R., Yamage M., Mwangi D. M., Honda Y., Mwakubambanya R. S., de Villiers E. P., Abuya E., Awino E., Gachanja J., Mbwika F., Muthiani A. M., Muriuki C., Nyanjui J. K., Onono F. O., Osaso J., Riitho V., Saya R. M., Ellis S. A., McKeever D. J., MacHugh N. D., Gilbert S. C., Audonnet J.-C., Morrison W. I., van der Bruggen P., Taracha E. L. N., Characterization of the Fine Specificity of Bovine CD8 T-Cell Responses to Defined Antigens from the Protozoan Parasite Theileria parva, 10.1128/iai.01244-07
  8. Graham S. P., Pelle R., Honda Y., Mwangi D. M., Tonukari N. J., Yamage M., Glew E. J., de Villiers E. P., Shah T., Bishop R., Abuya E., Awino E., Gachanja J., Luyai A. E., Mbwika F., Muthiani A. M., Ndegwa D. M., Njahira M., Nyanjui J. K., Onono F. O., Osaso J., Saya R. M., Wildmann C., Fraser C. M., Maudlin I., Gardner M. J., Morzaria S. P., Loosmore S., Gilbert S. C., Audonnet J.-C., van der Bruggen P., Nene V., Taracha E. L. N., Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes, 10.1073/pnas.0511273103
  9. MacHugh Niall D., Connelley Timothy, Graham Simon P., Pelle Roger, Formisano Principia, Taracha Evans L., Ellis Shirley A., McKeever Declan J., Burrells Alison, Morrison W. Ivan, CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity, 10.1002/eji.200939227
  10. Altman J. D., Moss P. A. H., Goulder P. J. R., Barouch D. H., McHeyzer-Williams M. G., Bell J. I., McMichael A. J., Davis M. M., Phenotypic Analysis of Antigen-Specific T Lymphocytes, 10.1126/science.274.5284.94
  11. Ellis Shirley A., Morrison W. Ivan, MacHugh Niall D., Birch James, Burrells Alison, Stear Michael J., Serological and molecular diversity in the cattle MHC class I region, 10.1007/s00251-005-0027-8
  12. Ellis S. A., Staines K. A., Stear M. J., Hensen E. J., Morrison W. I., DNA typing for BoLA class I using sequence-specific primers (PCR-SSP), 10.1111/j.1744-313x.1998.tb01154.x
  13. Goddeeris, Methods Cell Sci, 11, 101 (1988)
  14. Bensaid A., Hadam M., Bovine CD4 (BoCD4), 10.1016/0165-2427(91)90078-q
  15. MacHugh N.D., Sopp P., Bovine CD8 (BoCD8), 10.1016/0165-2427(91)90081-m
  16. Naessens, Immunology, 69, 525 (1990)
  17. Connelley Timothy, Storset Anne K, Pemberton Alan, MacHugh Niall, Brown Jeremy, Lund Hege, Morrison Ivan W, NKp46 defines ovine cells that have characteristics corresponding to NK cells, 10.1186/1297-9716-42-37
  18. Ellis J.A., Davis W.C., MacHugh N.D., Emery D.L., Kaushal A., Morrison W.I., Differentiation antigens on bovine mononuclear phagocytes identified by monoclonal antibodies, 10.1016/0165-2427(88)90118-3
  19. Connelley T., Burrells A., MacHugh Niall D., Morrison W.I., Use of a Pan-Vβ primer permits the amplification and sequencing of TCRβ chains expressed by bovine T-cell clones following a single semi-nested PCR reaction, 10.1016/j.vetimm.2008.05.025
  20. Connelley T., MacHugh Niall D., Burrells A., Morrison W.I., Dissection of the clonal composition of bovine αβ T cell responses using T cell receptor Vβ subfamily-specific PCR and heteroduplex analysis, 10.1016/j.jim.2008.02.015
  21. Quigley, Curr Protoc Immunol, Chapter 10, Unit10 33 (2011)
  22. Arden, Immunogenetics, 42, 455 (1995)
  23. Connelley Timothy, Aerts Jan, Law Andy, Morrison W Ivan, Genomic analysis reveals extensive gene duplication within the bovine TRB locus, 10.1186/1471-2164-10-192
  24. Macdonald Isabel K., Harkiolaki Maria, Hunt Lawrence, Connelley Timothy, Carroll A. Victoria, MacHugh Niall D., Graham Simon P., Jones E. Yvonne, Morrison W. Ivan, Flower Darren R., Ellis Shirley A., MHC Class I Bound to an Immunodominant Theileria parva Epitope Demonstrates Unconventional Presentation to T Cell Receptors, 10.1371/journal.ppat.1001149
  25. Park Min-Sun, Park Sung Yong, Miller Keith R., Collins Edward J., Lee Ha Youn, Accurate structure prediction of peptide–MHC complexes for identifying highly immunogenic antigens, 10.1016/j.molimm.2013.04.011
  26. Humphrey William, Dalke Andrew, Schulten Klaus, VMD: Visual molecular dynamics, 10.1016/0263-7855(96)00018-5
  27. Connelley T. K., MacHugh N. D., Pelle R., Weir W., Morrison W. I., Escape from CD8+ T Cell Response by Natural Variants of an Immunodominant Epitope from Theileria parva Is Predominantly Due to Loss of TCR Recognition, 10.4049/jimmunol.1102009
  28. Thomsen Martin, Lundegaard Claus, Buus Søren, Lund Ole, Nielsen Morten, MHCcluster, a method for functional clustering of MHC molecules, 10.1007/s00251-013-0714-9
  29. Svitek Nicholas, Hansen Andreas, Steinaa Lucilla, Saya Rosemary, Awino Elias, Nielsen Morten, Buus Søren, Nene Vishvanath, Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle, 10.1186/1297-9716-45-50
  30. Borbulevych Oleg Y., Insaidoo Francis K., Baxter Tiffany K., Powell Daniel J., Johnson Laura A., Restifo Nicholas P., Baker Brian M., Structures of MART-126/27–35 Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition, 10.1016/j.jmb.2007.07.025
  31. Derre L., Ferber M., Touvrey C., Devevre E., Zoete V., Leimgruber A., Romero P., Michielin O., Levy F., Speiser D. E., A Novel Population of Human Melanoma-Specific CD8 T Cells Recognizes Melan-AMART-1 Immunodominant Nonapeptide but Not the Corresponding Decapeptide, 10.4049/jimmunol.179.11.7635
  32. Borbulevych O. Y., Santhanagopolan S. M., Hossain M., Baker B. M., TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms, 10.4049/jimmunol.1101268
  33. Lee Jean K., Stewart-Jones Guillaume, Dong Tao, Harlos Karl, Di Gleria Kati, Dorrell Lucy, Douek Daniel C., van der Merwe P. Anton, Jones E. Yvonne, McMichael Andrew J., T Cell Cross-Reactivity and Conformational Changes during TCR Engagement, 10.1084/jem.20041251
  34. Tynan Fleur E, Reid Hugh H, Kjer-Nielsen Lars, Miles John J, Wilce Matthew C J, Kostenko Lyudmila, Borg Natalie A, Williamson Nicholas A, Beddoe Travis, Purcell Anthony W, Burrows Scott R, McCluskey James, Rossjohn Jamie, A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule, 10.1038/ni1432
  35. Pelle Roger, Graham Simon P., Njahira Moses N., Osaso Julius, Saya Rosemary M., Odongo David O., Toye Philip G., Spooner Paul R., Musoke Anthony J., Mwangi Duncan M., Taracha Evans L. N., Morrison W. Ivan, Weir William, Silva Joana C., Bishop Richard P., Two Theileria parva CD8 T Cell Antigen Genes Are More Variable in Buffalo than Cattle Parasites, but Differ in Pattern of Sequence Diversity, 10.1371/journal.pone.0019015
  36. Messaoudi I., Direct Link Between mhc Polymorphism, T Cell Avidity, and Diversity in Immune Defense, 10.1126/science.1076064
  37. Meyer-Olson Dirk, Shoukry Naglaa H., Brady Kristen W., Kim Helen, Olson Douglas P., Hartman Kelly, Shintani Ayumi K., Walker Christopher M., Kalams Spyros A., Limited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL Escape, 10.1084/jem.20040638
  38. Price David A., West Sadie M., Betts Michael R., Ruff Laura E., Brenchley Jason M., Ambrozak David R., Edghill-Smith Yvette, Kuroda Marcelo J., Bogdan Derek, Kunstman Kevin, Letvin Norman L., Franchini Genoveffa, Wolinsky Steven M., Koup Richard A., Douek Daniel C., T Cell Receptor Recognition Motifs Govern Immune Escape Patterns in Acute SIV Infection, 10.1016/j.immuni.2004.10.010
  39. Li X., Liu J., Qi J., Gao F., Li Q., Li X., Zhang N., Xia C., Gao G. F., Two Distinct Conformations of a Rinderpest Virus Epitope Presented by Bovine Major Histocompatibility Complex Class I N*01801: a Host Strategy To Present Featured Peptides, 10.1128/jvi.00030-11
  40. Alanio C., Lemaitre F., Law H. K. W., Hasan M., Albert M. L., Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies, 10.1182/blood-2009-10-251124
  41. Taracha, PhD Thesis, University of Brunel, UK, 89 (1991)