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Effects of BM-573 on Endothelial Dependent Relaxation and Increased Blood Pressure at Early Stages of Atherosclerosis.

Bibliographic reference Romero, Miguel ; Leon-Gomez, Elvira ; Lobysheva, Irina ; Rath, Géraldine ; Dogné, Jean-Michel ; et. al. Effects of BM-573 on Endothelial Dependent Relaxation and Increased Blood Pressure at Early Stages of Atherosclerosis.. In: PLoS One, Vol. 11, no.3, p. e0152579 (2016)
Permanent URL http://hdl.handle.net/2078.1/173190
  1. Landmesser U., Endothelial Function: A Critical Determinant in Atherosclerosis?, 10.1161/01.cir.0000129501.88485.1f
  2. Yang Z., Ming X.-F., Recent Advances in Understanding Endothelial Dysfunction in Atherosclerosis, 10.3121/cmr.4.1.53
  3. Alp N. J., McAteer M. A., Khoo J., Choudhury R. P., Channon K. M., Increased Endothelial Tetrahydrobiopterin Synthesis by Targeted Transgenic GTP-Cyclohydrolase I Overexpression Reduces Endothelial Dysfunction and Atherosclerosis in ApoE-Knockout Mice, 10.1161/01.atv.0000115637.48689.77
  4. Belton O., Byrne D., Kearney D., Leahy A., Fitzgerald D. J., Cyclooxygenase-1 and -2-Dependent Prostacyclin Formation in Patients With Atherosclerosis, 10.1161/01.cir.102.8.840
  5. Reilly M. P., Pratico D., Delanty N., DiMinno G., Tremoli E., Rader D., Kapoor S., Rokach J., Lawson J., FitzGerald G. A., Increased Formation of Distinct F2 Isoprostanes in Hypercholesterolemia, 10.1161/01.cir.98.25.2822
  6. Félétou Michel, Vanhoutte Paul M, Verbeuren Tony J, The Thromboxane/Endoperoxide Receptor (TP): The Common Villain : , 10.1097/fjc.0b013e3181d8bc8a
  7. Zhang M., Song P., Xu J., Zou M.-H., Activation of NAD(P)H Oxidases by Thromboxane A2 Receptor Uncouples Endothelial Nitric Oxide Synthase, 10.1161/atvbaha.110.207712
  8. Cayatte A. J., Du Y., Oliver-Krasinski J., Lavielle G., Verbeuren T. J., Cohen R. A., The Thromboxane Receptor Antagonist S18886 but Not Aspirin Inhibits Atherogenesis in Apo E-Deficient Mice : Evidence That Eicosanoids Other Than Thromboxane Contribute to Atherosclerosis, 10.1161/01.atv.20.7.1724
  9. Dogné Jean-Michel, Hanson Julien, Pratico Domenico, Thromboxane, prostacyclin and isoprostanes: therapeutic targets in atherogenesis, 10.1016/j.tips.2005.10.001
  10. Gendron M.-E., Thorin E., A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice, 10.1152/ajpheart.00352.2007
  11. Lesault Pierre-François, Boyer Laurent, Pelle Gabriel, Covali-Noroc Ala, Rideau Dominique, Akakpo Servais, Teiger Emmanuel, Dubois-Randé Jean-Luc, Adnot Serge, Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis : Terutroban improves endothelial function, 10.1111/j.1365-2125.2010.03858.x
  12. Dogne J.-M., Pharmacological Characterization of N-tert-Butyl-N'-[2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl]urea (BM-573), a Novel Thromboxane A2 Receptor Antagonist and Thromboxane Synthase Inhibitor in a Rat Model of Arterial Thrombosis and Its Effects on Bleeding Time, 10.1124/jpet.103.063610
  13. Ghuysen A., Effect of BM-573 [N-Terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism, 10.1124/jpet.104.066852
  14. Cherdon Céline, Rolin Stéphanie, Hanson Julien, Ooms Annie, de Leval Laurence, Drion Pierre, Michiels Carine, Pirotte Bernard, Masereel Bernard, Sakalihassan Natzi, Defraigne Jean-Olivier, Dogné Jean-Michel, BM-573 inhibits the development of early atherosclerotic lesions in Apo E deficient mice by blocking TP receptors and thromboxane synthase, 10.1016/j.prostaglandins.2011.03.001
  15. Cyrus Tillmann, Yao Yuemang, Ding Tao, Dogné Jean Michel, Praticò Domenico, A novel thromboxane receptor antagonist and synthase inhibitor, BM-573, reduces development and progression of atherosclerosis in LDL receptor deficient mice, 10.1016/j.ejphar.2006.12.024
  16. Dessy C., Endothelial  3-Adrenoreceptors Mediate Nitric Oxide-Dependent Vasorelaxation of Coronary Microvessels in Response to the Third-Generation  -Blocker Nebivolol, 10.1161/circulationaha.104.532960
  17. Desjardins Fanny, Lobysheva Irina, Pelat Michel, Gallez Bernard, Feron Olivier, Dessy Chantal, Balligand Jean-Luc, Control of blood pressure variability in caveolin-1-deficient mice: role of nitric oxide identified in vivo through spectral analysis, 10.1093/cvr/cvn080
  18. Romero Miguel, Jiménez Rosario, Sánchez Manuel, López-Sepúlveda Rocío, Zarzuelo Maria José, O’Valle Francisco, Zarzuelo Antonio, Pérez-Vizcaíno Francisco, Duarte Juan, Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC, 10.1016/j.atherosclerosis.2008.03.007
  19. Rouaud Florian, Romero-Perez Miguel, Wang Huan, Lobysheva Irina, Ramassamy Booma, Henry Etienne, Tauc Patrick, Giacchero Damien, Boucher Jean-Luc, Deprez Eric, Rocchi Stéphane, Slama-Schwok Anny, Regulation of NADPH-dependent Nitric Oxide and reactive oxygen species signalling in endothelial and melanoma cells by a photoactive NADPH analogue, 10.18632/oncotarget.2525
  20. Romero Miguel, Jiménez Rosario, Hurtado Belén, Moreno Juan Manuel, Rodríguez-Gómez Isabel, López-Sepúlveda Rocío, Zarzuelo Antonio, Pérez-Vizcaino Francisco, Tamargo Juan, Vargas Félix, Duarte Juan, Lack of beneficial metabolic effects of quercetin in adult spontaneously hypertensive rats, 10.1016/j.ejphar.2009.11.006
  21. Pelat M., Rosuvastatin Decreases Caveolin-1 and Improves Nitric Oxide-Dependent Heart Rate and Blood Pressure Variability in Apolipoprotein E-/- Mice In Vivo, 10.1161/01.cir.0000065601.83526.3e
  22. Cui Wenhao, Matsuno Kuniharu, Iwata Kazumi, Ibi Masakazu, Katsuyama Masato, Kakehi Tomoko, Sasaki Mika, Ikami Kanako, Zhu Kai, Yabe-Nishimura Chihiro, NADPH Oxidase Isoforms and Anti-hypertensive Effects of Atorvastatin Demonstrated in Two Animal Models, 10.1254/jphs.09148fp
  23. Jiang Fan, Guo Yanan, Salvemini Daniela, Dusting Gregory J, Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein(E)-deficient mice, 10.1038/sj.bjp.0705354
  24. Kawashima Seinosuke, Malfunction of Vascular Control in Lifestyle-Related Diseases: Endothelial Nitric Oxide (NO) Synthase/NO System in Atherosclerosis, 10.1254/jphs.fmj04006x6
  25. Meir K. S., Atherosclerosis in the Apolipoprotein E-Deficient Mouse: A Decade of Progress, 10.1161/01.atv.0000128849.12617.f4
  26. Chen X., Zhang H., McAfee S., Zhang C., The reciprocal relationship between adiponectin and LOX-1 in the regulation of endothelial dysfunction in ApoE knockout mice, 10.1152/ajpheart.01096.2009
  27. Raman Kathleen G., Gandley Robin E., Rohland Jennifer, Zenati Mazen S., Tzeng Edith, Early hypercholesterolemia contributes to vasomotor dysfunction and injury associated atherogenesis that can be inhibited by nitric oxide, 10.1016/j.jvs.2010.09.038
  28. Beleznai Timea, Takano Hiromichi, Hamill Claire, Yarova Polina, Douglas Gillian, Channon Keith, Dora Kim, Enhanced K+-channel-mediated endothelium-dependent local and conducted dilation of small mesenteric arteries from ApoE−/− mice, 10.1093/cvr/cvr181
  29. Laursen J. B., Somers M., Kurz S., McCann L., Warnholtz A., Freeman B. A., Tarpey M., Fukai T., Harrison D. G., Endothelial Regulation of Vasomotion in ApoE-Deficient Mice : Implications for Interactions Between Peroxynitrite and Tetrahydrobiopterin, 10.1161/01.cir.103.9.1282
  30. Creager M A, Cooke J P, Mendelsohn M E, Gallagher S J, Coleman S M, Loscalzo J, Dzau V J, Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans., 10.1172/jci114688
  31. Belhassen Laurent, Pelle Gabriel, Dubois-Rande Jean-Luc, Adnot Serge, Improved endothelial function by the thromboxane a2receptor antagonist s 18886 in patients with coronary artery disease treated with aspirin, 10.1016/s0735-1097(03)00048-2
  32. Feletou M., Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture), 10.1152/ajpheart.00292.2006
  33. Gelosa P., Ballerio R., Banfi C., Nobili E., Gianella A., Pignieri A., Brioschi M., Guerrini U., Castiglioni L., Blanc-Guillemaud V., Lerond L., Tremoli E., Sironi L., Terutroban, a Thromboxane/Prostaglandin Endoperoxide Receptor Antagonist, Increases Survival in Stroke-Prone Rats by Preventing Systemic Inflammation and Endothelial Dysfunction: Comparison with Aspirin and Rosuvastatin, 10.1124/jpet.110.165787
  34. Drouin Annick, Farhat Nada, Bolduc Virginie, Thorin-Trescases Nathalie, Gillis Marc-Antoine, Villeneuve Louis, Nguyen Albert, Thorin Eric, Up-regulation of thromboxane A2 impairs cerebrovascular eNOS function in aging atherosclerotic mice, 10.1007/s00424-011-0973-y
  35. Levine G. N., Frei B., Koulouris S. N., Gerhard M. D., Keaney J. F., Vita J. A., Ascorbic Acid Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease, 10.1161/01.cir.93.6.1107
  36. Qian H., Neplioueva V., Shetty G. A., Channon K. M., George S. E., Nitric Oxide Synthase Gene Therapy Rapidly Reduces Adhesion Molecule Expression and Inflammatory Cell Infiltration in Carotid Arteries of Cholesterol-Fed Rabbits, 10.1161/01.cir.99.23.2979
  37. Song Ping, Zhang Miao, Wang Shuangxi, Xu Jian, Choi Hyoung Chul, Zou Ming-Hui, Thromboxane A2Receptor Activates a Rho-associated Kinase/LKB1/PTEN Pathway to Attenuate Endothelium Insulin Signaling, 10.1074/jbc.m109.012583
  38. Liu Cui Qing, Leung Fung Ping, Wong Siu Ling, Wong Wing Tak, Lau Chi Wai, Lu Limin, Yao Xiaoqiang, Yao Tai, Huang Yu, Thromboxane prostanoid receptor activation impairs endothelial nitric oxide-dependent vasorelaxations: The role of Rho kinase, 10.1016/j.bcp.2009.04.022
  39. Barry-Lane Patricia A., Patterson Cam, van der Merwe Marié, Hu Zhaoyong, Holland Stephen M., Yeh Edward T.H., Runge Marschall S., p47phox is required for atherosclerotic lesion progression in ApoE–/– mice, 10.1172/jci200111927
  40. Terashima M., Ohashi Y., Azumi H., Otsui K., Kaneda H., Awano K., Kobayashi S., Honjo T., Suzuki T., Maeda K., Yokoyama M., Inoue N., Impact of NAD(P)H Oxidase-Derived Reactive Oxygen Species on Coronary Arterial Remodeling: A Comparative Intravascular Ultrasound and Histochemical Analysis of Atherosclerotic Lesions, 10.1161/circinterventions.108.799502
  41. Félétou Michel, Huang Yu, Vanhoutte Paul M, Endothelium-mediated control of vascular tone: COX-1 and COX-2 products : COX-1, COX-2 and endothelial dysfunction, 10.1111/j.1476-5381.2011.01276.x
  42. Linton M, Cyclooxygenase-2 and inflammation in atherosclerosis, 10.1016/j.coph.2003.12.003
  43. Wong Wing Tak, Tian Xiao Yu, Huang Yu, Endothelial Dysfunction in Diabetes and Hypertension : Cross Talk in RAS, BMP4, and ROS-dependent COX-2–derived Prostanoids, 10.1097/fjc.0b013e31827fe46e
  44. Delannoy E., Courtois A., Freund-Michel V., Leblais V., Marthan R., Muller B., Hypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors, 10.1093/cvr/cvp292
  45. Petri Marcelo H., Tellier Céline, Michiels Carine, Ellertsen Ingvill, Dogné Jean-Michel, Bäck Magnus, Effects of the dual TP receptor antagonist and thromboxane synthase inhibitor EV-077 on human endothelial and vascular smooth muscle cells, 10.1016/j.bbrc.2013.10.078
  46. Arruda R. M.P., Peotta V. A., Meyrelles S. S., Vasquez E. C., Evaluation of Vascular Function in Apolipoprotein E Knockout Mice With Angiotensin-Dependent Renovascular Hypertension, 10.1161/01.hyp.0000182154.61862.52
  47. Martínez-Miguel Patricia, Raoch Viviana, Zaragoza Carlos, Valdivielso Jose Manuel, Rodríguez-Puyol Manuel, Rodríguez-Puyol Diego, López-Ongil Susana, Endothelin-converting enzyme-1 increases in atherosclerotic mice: potential role of oxidized low density lipoproteins, 10.1194/jlr.m800215-jlr200