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Are fibromyalgia patients cognitively impaired? Objective and subjective neuropsychological evidence.

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Tesio, Valentina Torta, Diana [UCL] Colonna, Fabrizio Leombruni, Paolo Ghiggia, Ada Castelli, Lorys

OBJECTIVE: Patients with fibromyalgia (FM) syndrome often report a cluster of cognitive disorders that strongly interferes with their work and daily life, but the relationship between impaired cognitive function and self-reported dysfunction remains unclear. We aimed to investigate the presence of cognitive impairments in patients with FM and to analyze the relationship between the impairments and their evaluation by the patients through a comparison with a group of healthy controls. METHODS: In total, 30 FM patients and 30 healthy controls performed a neuropsychological and clinical evaluation of short-term, long-term, and working memory; executive function; and self-evaluation of cognitive impairment and depressive and anxiety symptoms. To thoroughly investigate executive function, we adopted the Miyake model that identifies 4 domains: shifting, inhibition, updating, and access. RESULTS: Our results confirmed the presence of impairments of attention, long-term memory, working memory, and shifting and updating executive functions in FM patients compared with healthy controls. These impairments are reflected in patient reports independently of depressive symptoms. CONCLUSION: The use of a self-reported questionnaire in clinical practice would provide a first and easy screen for the presence of cognitive impairment in FM patients and, in most cases, obviate the need for a time-consuming full neuropsychological test battery.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 2015
Language Anglais
Journal information "Arthritis Care & Research" - Vol. 67, no. 1, p. 143-150 (2015)
Peer reviewed yes
Publisher JohnWiley & Sons, Inc. (Hoboken)
issn 2151-464X
e-issn 2151-4658
Publication status Publié
Affiliation University of Turin - Department of Psychology
MESH Subject Adult ; Neuropsychological Tests ; Self Report ; Aged ; Cognition Disorders ; Executive Function ; Female ; Fibromyalgia ; Humans ; Memory ; Middle Aged
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Bibliographic reference Tesio, Valentina ; Torta, Diana ; Colonna, Fabrizio ; Leombruni, Paolo ; Ghiggia, Ada ; et. al. Are fibromyalgia patients cognitively impaired? Objective and subjective neuropsychological evidence.. In: Arthritis Care & Research, Vol. 67, no. 1, p. 143-150 (2015)
Permanent URL http://hdl.handle.net/2078/170148