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Occult HBV reactivation induced by ibrutinib treatment : a case report

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Ngoma, Patrick de Jesus [UCL] Kabamba-Mukadi, Benoît [UCL] Dahlqvist, Géraldine [UCL] Sempoux, Christine [UCL] Lanthier, Nicolas [UCL] Shindano, Tony [UCL] Van Den Neste, Eric [UCL] Horsmans, Yves [UCL]

Ibrutinib is a small molecule that has been recently developped for the treatment of B cell malignancies. Common side effects are diarrhoea, nausea, fatigue, infections, neutropenia and thrombocytopenia. Here we report the first case of Hepatitis B virus reactivation in a 80 years old chronic lymphocytic leukaemia patient receiving ibrutinib, suggesting that such treatment must be associated with HBV screening.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2015
Language Anglais
Journal information "Acta Gastro-Enterologica Belgica" - Vol. 78, no. 4, p. 424-426 (2015)
Peer reviewed yes
Publisher Universa Press ((Belgium) Wetteren)
issn 1784-3227
e-issn 0001-5644
Publication status Publié
Affiliations UCL - (SLuc) Service d'hépato-gastro-entérologie
UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie
UCL - SSS/IREC/MBLG - Pôle de Microbiologie médicale
UCL - (SLuc) Service de microbiologie
UCL - SSS/IREC/ECLI - Pôle d'Essais cliniques
UCL - SSS/DDUV/BCHM - Biochimie-Recherche métabolique
UCL - (SLuc) Service d'anatomie pathologique
UCL - (SLuc) Service d'hématologie
Keywords Hepatitis B ; ibrutinib
Links
Bibliographic reference Ngoma, Patrick de Jesus ; Kabamba-Mukadi, Benoît ; Dahlqvist, Géraldine ; Sempoux, Christine ; Lanthier, Nicolas ; et. al. Occult HBV reactivation induced by ibrutinib treatment : a case report. In: Acta Gastro-Enterologica Belgica, Vol. 78, no. 4, p. 424-426 (2015)
Permanent URL http://hdl.handle.net/2078.1/169609