Méthodes de colorations vitales des muqueuses duodénales et intestinales

In the seventies in Europe, after the Japanese, duodenal mucosa staining methods were focused on minute lesions and duodenal ulcer. The availability of more powerful acid secretion inhibitors (PPI) and H. pylori eradication have decreased the interest for vital coloration. However, the diagnosis of duodenal and jejunal villous atrophic lesions required vital dyes and spraying coloration techniques. Nowadays, the use of megapixel videoendoscope with magnifying optical system associated to chromoscopy is powerful for the diagnosis and the follow-up of total or subtotal villous atrophis in celiac disease or its variants (latent CD, refractory sprue) and in other malabsorption syndrome diseases (tropical sprue), etc.