User menu

A randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of long-term treatment with prucalopride

Bibliographic reference Piessevaux, Hubert ; Corazziari, Enrico Stefano ; Rey, Enrique ; Simren, Magnus ; Wiechowska-Kozlowska, Anna ; et. al. A randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, and tolerability of long-term treatment with prucalopride. In: Neurogastroenterology and Motility, Vol. 27, no. 6, p. 805-815 (2015)
Permanent URL
  1. Choung Rok Seon, Locke G. Richard, Rey Enrique, Schleck Cathy D., Baum Charles, Zinsmeister Alan R., Talley Nicholas J., Factors Associated With Persistent and Nonpersistent Chronic Constipation, Over 20 Years, 10.1016/j.cgh.2011.12.041
  2. JOHANSON J. F., KRALSTEIN J., Chronic constipation: a survey of the patient perspective : PATIENT PERSPECTIVE ON CONSTIPATION, 10.1111/j.1365-2036.2006.03238.x
  3. Müller-Lissner S., Tack J., Feng Y., Schenck F., Specht Gryp R., Levels of satisfaction with current chronic constipation treatment options in Europe - an internet survey, 10.1111/apt.12124
  4. Müller-lissner S., Rykx A., Kerstens R., Vandeplassche L., A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation : Prucalopride in elderly constipated patients, 10.1111/j.1365-2982.2010.01533.x
  5. Tack J, van Outryve M, Beyens G, Kerstens R, Vandeplassche L, Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives, 10.1136/gut.2008.162404
  6. Camilleri Michael, Kerstens René, Rykx An, Vandeplassche Lieve, A Placebo-Controlled Trial of Prucalopride for Severe Chronic Constipation, 10.1056/nejmoa0800670
  7. QUIGLEY E. M. M., VANDEPLASSCHE L., KERSTENS R., AUSMA J., Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation - a 12-week, randomized, double-blind, placebo-controlled study, 10.1111/j.1365-2036.2008.03884.x
  8. Tack Jan, Quigley Eamonn, Camilleri Michael, Vandeplassche Lieve, Kerstens René, Efficacy and safety of oral prucalopride in women with chronic constipation in whom laxatives have failed: an integrated analysis, 10.1177/2050640612474651
  9. Ke M., Zou D., Yuan Y., Li Y., Lin L., Hao J., Hou X., Kim H. J., Prucalopride in the treatment of chronic constipation in patients from the Asia-Pacific region: a randomized, double-blind, placebo-controlled study : Prucalopride treatment for chronic constipation, 10.1111/j.1365-2982.2012.01983.x
  10. Camilleri M., Van Outryve M. J., Beyens G., Kerstens R., Robinson P., Vandeplassche L., Clinical trial: the efficacy of open-label prucalopride treatment in patients with chronic constipation - follow-up of patients from the pivotal studies : Clinical trial: long-term prucalopride in chronic constipation, 10.1111/j.1365-2036.2010.04455.x
  11. ICH harmonised tripartite guidelines for good clinical practice 1996
  12. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects
  13. Lewis S. J., Heaton K. W., Stool Form Scale as a Useful Guide to Intestinal Transit Time, 10.3109/00365529709011203
  14. L. Frank, L. Kleinman, C. Farup, L., Psychometric Validation of a Constipation Symptom Assessment Questionnaire, 10.1080/003655299750025327
  15. dubois d., gilet h., viala-danten m., tack j., Psychometric performance and clinical meaningfulness of the Patient Assessment of Constipation – Quality of Life questionnaire in prucalopride (RESOLOR®) trials for chronic constipation, 10.1111/j.1365-2982.2009.01408.x
  16. Marquis Patrick, De La Loge Christine, Dubois Dominique, McDermott Anne, Chassany Olivier, Development and validation of the Patient Assessment of Constipation Quality of Life questionnaire, 10.1080/00365520510012208