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Management of gynecological cancers during pregnancy

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Han, Sileny N. Verheecke, Magali Vandenbroucke, Tineke Mhallem Gziri, Mina [UCL] Van Calsteren, Kristel Amant, Frédéric

The diagnosis of a gynecological malignancy during pregnancy is rare but not uncommon. Cancer treatment during pregnancy is possible, but both maternal and fetal interests need to be respected. Different treatment plans may be justifiable and multidisciplinary treatment is advised. Clinical trials are virtually impossible, and current evidence is mainly based on small case series and expert opinion. Individualization of treatment is necessary and based on tumor type, stage, and gestational age at time of diagnosis. Termination of pregnancy is not necessary in most cases. Surgery and chemotherapy (second trimester and onwards) are possible types of treatment during pregnancy. Radiotherapy of the pelvic area is not compatible with an ongoing pregnancy. This article discusses the current recommendations for the management of gynecological malignancies (cervical, ovarian, and vulvar cancers) during pregnancy.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2014
Language Anglais
Journal information "Current Oncology Reports" - Vol. 16, no. 12, p. 415 [1-10] (2014)
Peer reviewed yes
Publisher Current Medicine Group LLC ((United States) Philadelphia, PA)
issn 1523-3790
e-issn 1534-6269
Publication status Publié
Affiliation UCL - (SLuc) Service d'obstétrique
Links
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Bibliographic reference Han, Sileny N. ; Verheecke, Magali ; Vandenbroucke, Tineke ; Mhallem Gziri, Mina ; Van Calsteren, Kristel ; et. al. Management of gynecological cancers during pregnancy. In: Current Oncology Reports, Vol. 16, no. 12, p. 415 [1-10] (2014)
Permanent URL http://hdl.handle.net/2078.1/164236