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Roux-en-Y gastric bypass surgery in rats alters gut microbiota profile along the intestine

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Osto, Melania Abegg, Kathrin Bueter, Marco le Roux, Carel W. Cani, Patrice D. [UCL] Lutz, Thomas A.

Roux-en-Y gastric bypass (RYGB) surgery might modify the gut microbiota composition differently in the three distinct anatomical sections of the small intestine compared to sham surgery. We showed that RYGB induced changes in the microbiota of the alimentary limb and the common channel resembling those seen after prebiotic treatment or weight loss by dieting. These changes may be associated with altered production of intestinal hormones known to control energy balance. Postsurgical modulation of gut microbiota may significantly contribute to the beneficial metabolic effects of RYGB surgery. © 2013 Elsevier Inc.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2013
Language Anglais
Journal information "Physiology & Behavior" - Vol. 119, p. 92-96 (2013)
Peer reviewed yes
Publisher Elsevier Inc.
e-issn 1873-507X
issn 0031-9384
Publication status Publié
Affiliation UCL - SSS/LDRI - Louvain Drug Research Institute
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Bibliographic reference Osto, Melania ; Abegg, Kathrin ; Bueter, Marco ; le Roux, Carel W. ; Cani, Patrice D. ; et. al. Roux-en-Y gastric bypass surgery in rats alters gut microbiota profile along the intestine. In: Physiology & Behavior, Vol. 119, p. 92-96 (2013)
Permanent URL http://hdl.handle.net/2078.1/160666