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Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein

Bibliographic reference Corbet, Cyril ; Demont, Yohann ; Page, Adeline ; Ataman-Önal, Yasemin ; Choquet-Kastylevsky, Genevieve ; et. al. Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein. In: Journal of Biological Chemistry, Vol. 287, no. 3, p. 1923-1931 (2011)
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  1. Shooter Eric M., Early Days of the Nerve Growth Factor Proteins, 10.1146/annurev.neuro.24.1.601
  2. Dollé Laurent, El Yazidi-Belkoura Ikram, Adriaenssens Eric, Nurcombe Victor, Hondermarck Hubert, Nerve growth factor overexpression and autocrine loop in breast cancer cells, 10.1038/sj.onc.1206805
  3. Yazidi-Belkoura Ikram El, Adriaenssens Eric, Dollé Laurent, Descamps Simon, Hondermarck Hubert, Tumor Necrosis Factor Receptor-associated Death Domain Protein Is Involved in the Neurotrophin Receptor-mediated Antiapoptotic Activity of Nerve Growth Factor in Breast Cancer Cells, 10.1074/jbc.m300631200
  4. Naderi A., Teschendorff A. E., Beigel J., Cariati M., Ellis I. O., Brenton J. D., Caldas C., BEX2 Is Overexpressed in a Subset of Primary Breast Cancers and Mediates Nerve Growth Factor/Nuclear Factor- B Inhibition of Apoptosis in Breast Cancer Cell Lines, 10.1158/0008-5472.can-06-4394
  5. Tagliabue Elda, Castiglioni Fabio, Ghirelli Cristina, Modugno Michele, Asnaghi Laura, Somenzi Giulia, Melani Cecilia, Ménard Sylvie, Nerve Growth Factor Cooperates with p185HER2in Activating Growth of Human Breast Carcinoma Cells, 10.1074/jbc.275.8.5388
  6. Chiarenza, Cancer Res., 61, 3002 (2001)
  7. Montano X, Repression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferation, 10.1038/onc.2009.143
  8. Aragona Marcello, Panetta Stefania, Silipigni Anna Maria, Romeo Domenico Leo, Pastura Giuseppe, Mesiti Mario, Cascinu Stefano, La Torre Francesco, Nerve Growth Factor Receptor Immunoreactivity in Breast Cancer Patients, 10.1081/cnv-100106144
  9. Davidson Ben, Reich Reuven, Lazarovici Philip, Ann Flørenes Vivi, Nielsen Søren, Nesland Jahn M., Altered Expression and Activation of the Nerve Growth Factor Receptors TrkA and p75 Provide the First Evidence of Tumor Progression to Effusion in Breast Carcinoma, 10.1023/b:brea.0000010704.17479.8a
  10. Descamps, Cancer Res., 61, 4337 (2001)
  11. Adriaenssens E., Vanhecke E., Saule P., Mougel A., Page A., Romon R., Nurcombe V., Le Bourhis X., Hondermarck H., Nerve Growth Factor Is a Potential Therapeutic Target in Breast Cancer, 10.1158/0008-5472.can-07-1183
  12. Lee R., Regulation of Cell Survival by Secreted Proneurotrophins, 10.1126/science.1065057
  13. Pagadala P. C., Dvorak L. A., Neet K. E., Construction of a mutated pro-nerve growth factor resistant to degradation and suitable for biophysical and cellular utilization, 10.1073/pnas.0604139103
  14. Hempstead Barbara, Dissecting the Diverse Actions of Pro- and Mature Neurotrophins, 10.2174/156720506775697061
  15. Bresnahan P. A., Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro- beta-NGF in vivo, 10.1083/jcb.111.6.2851
  16. SEIDAH Nabil G., BENJANNET Suzanne, PAREEK Sangeeta, SAVARIA Diane, HAMELIN Josée, GOULET Brigitte, LALIBERTÉ Jacynthe, LAZURE Claude, CHRÉTIEN Michel, MURPHY Richard A., Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases, 10.1042/bj3140951
  17. Bruno M. A., Cuello A. C., Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade, 10.1073/pnas.0510645103
  18. Lagadec C, Meignan S, Adriaenssens E, Foveau B, Vanhecke E, Romon R, Toillon R -A, Oxombre B, Hondermarck H, Le Bourhis X, TrkA overexpression enhances growth and metastasis of breast cancer cells, 10.1038/onc.2009.61
  19. Verbeke Stéphanie, Meignan Samuel, Lagadec Chann, Germain Emmanuelle, Hondermarck Hubert, Adriaenssens Eric, Le Bourhis Xuefen, Overexpression of p75NTR increases survival of breast cancer cells through p21waf1, 10.1016/j.cellsig.2010.07.014
  20. Feng Dan, Kim Taeho, Özkan Engin, Light Matthew, Torkin Risa, Teng Kenneth K., Hempstead Barbara L., Garcia K. Christopher, Molecular and Structural Insight into proNGF Engagement of p75NTR and Sortilin, 10.1016/j.jmb.2009.12.030
  21. Truzzi Francesca, Marconi Alessandra, Lotti Roberta, Dallaglio Katiuscia, French Lars E., Hempstead Barbara L., Pincelli Carlo, Neurotrophins and Their Receptors Stimulate Melanoma Cell Proliferation and Migration, 10.1038/jid.2008.21
  22. Masoudi Raheleh, Ioannou Maria S., Coughlin Michael D., Pagadala Promila, Neet Kenneth E., Clewes Oliver, Allen Shelley J., Dawbarn David, Fahnestock Margaret, Biological Activity of Nerve Growth Factor Precursor Is Dependent upon Relative Levels of Its Receptors, 10.1074/jbc.m109.007104
  23. Harrington A. W., Leiner B., Blechschmitt C., Arevalo J. C., Lee R., Morl K., Meyer M., Hempstead B. L., Yoon S. O., Giehl K. M., From The Cover: Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury, 10.1073/pnas.0305755101
  24. Vaegter Christian B, Jansen Pernille, Fjorback Anja W, Glerup Simon, Skeldal Sune, Kjolby Mads, Richner Mette, Erdmann Bettina, Nyengaard Jens R, Tessarollo Lino, Lewin Gary R, Willnow Thomas E, Chao Moses V, Nykjaer Anders, Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling, 10.1038/nn.2689
  25. Weigelt Britta, Peterse Johannes L., van't Veer Laura J., Breast cancer metastasis: markers and models, 10.1038/nrc1670
  26. Kim Lori C., Song Lanxi, Haura Eric B., Src kinases as therapeutic targets for cancer, 10.1038/nrclinonc.2009.129
  27. Dillon R. L., Muller W. J., Distinct Biological Roles for the Akt Family in Mammary Tumor Progression, 10.1158/0008-5472.can-10-0266
  28. Matrone C., Marolda R., Ciafre S., Ciotti M. T., Mercanti D., Calissano P., Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation, 10.1073/pnas.0904998106
  29. Vanhecke E., Adriaenssens E., Verbeke S., Meignan S., Germain E., Berteaux N., Nurcombe V., Le Bourhis X., Hondermarck H., Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Are Expressed in Breast Cancer and Can Be Targeted to Inhibit Tumor Cell Survival, 10.1158/1078-0432.ccr-10-1890
  30. Romon Rodrigue, Adriaenssens Eric, Lagadec Chann, Germain Emmanuelle, Hondermarck Hubert, Le Bourhis Xuefen, Nerve growth factor promotes breast cancer angiogenesis by activating multiple pathways, 10.1186/1476-4598-9-157
  31. Bloom Aaron P., Jimenez-Andrade Juan M., Taylor Reid N., Castañeda-Corral Gabriela, Kaczmarska Magdalena J., Freeman Katie T., Coughlin Kathleen A., Ghilardi Joseph R., Kuskowski Michael A., Mantyh Patrick W., Breast Cancer-Induced Bone Remodeling, Skeletal Pain, and Sprouting of Sensory Nerve Fibers, 10.1016/j.jpain.2010.12.016
  32. Nykjaer Anders, Lee Ramee, Teng Kenneth K., Jansen Pernille, Madsen Peder, Nielsen Morten S., Jacobsen Christian, Kliemannel Marco, Schwarz Elisabeth, Willnow Thomas E., Hempstead Barbara L., Petersen Claus M., Sortilin is essential for proNGF-induced neuronal cell death, 10.1038/nature02319
  33. Pedraza Carlos E., Podlesniy Petar, Vidal Noemí, Arévalo Juan Carlos, Lee Ramee, Hempstead Barbara, Ferrer Isidre, Iglesias Montse, Espinet Carme, Pro-NGF Isolated from the Human Brain Affected by Alzheimer's Disease Induces Neuronal Apoptosis Mediated by p75NTR, 10.1016/s0002-9440(10)62275-4
  34. Quistgaard Esben M, Madsen Peder, Grøftehauge Morten K, Nissen Poul, Petersen Claus M, Thirup Søren S, Ligands bind to Sortilin in the tunnel of a ten-bladed β-propeller domain, 10.1038/nsmb.1543
  35. Boutilier Jacqueline, Ceni Claire, Pagdala Promila C., Forgie Alison, Neet Kenneth E., Barker Philip A., Proneurotrophins Require Endocytosis and Intracellular Proteolysis to Induce TrkA Activation, 10.1074/jbc.m710018200
  36. Clewes, J. Neurochem., 107, 1124 (2008)
  37. Descamps Simon, Toillon Robert-Alain, Adriaenssens Eric, Pawlowski Valérie, Cool Simon M., Nurcombe Victor, Le Bourhis Xuefen, Boilly Bénoni, Peyrat Jean-Philippe, Hondermarck Hubert, Nerve Growth Factor Stimulates Proliferation and Survival of Human Breast Cancer Cells through Two Distinct Signaling Pathways, 10.1074/jbc.m010499200