Vigneron, Nathalie
[UCL]
With the recent developments of adoptive T cell therapies and the use of new monoclonal antibodies against the immune checkpoints, immunotherapy is at a turning point. Key players for the success of these therapies are the cytolytic T lymphocytes, which are a subset of T cells able to recognize and kill tumor cells. Here, I review the nature of the antigenic peptides recognized by these T cells and the processes involved in their presentation. I discuss the importance of understanding how each antigenic peptide is processed in the context of immunotherapy and vaccine delivery.
Bibliographic reference |
Vigneron, Nathalie. Human tumor antigens and cancer immunotherapy. In: BioMed Research International, Vol. 2015, p. 1-17 (2015) |
Permanent URL |
http://hdl.handle.net/2078.1/157309 |