User menu

Therapeutic Vaccination with TNF-Kinoid in TNF Antagonist-Resistant Rheumatoid Arthritis: A Phase II Randomized, Controlled Clinical Trial.

Bibliographic reference Durez, Patrick ; Vandepapeliere, Pierre ; Miranda, Pedro ; Toncheva, Antoaneta ; Berman, Alberto ; et. al. Therapeutic Vaccination with TNF-Kinoid in TNF Antagonist-Resistant Rheumatoid Arthritis: A Phase II Randomized, Controlled Clinical Trial.. In: PLoS One, Vol. 9, no.12 (2014)
Permanent URL
  1. Scott David L, Wolfe Frederick, Huizinga Tom WJ, Rheumatoid arthritis, 10.1016/s0140-6736(10)60826-4
  2. McInnes Iain B., Schett Georg, The Pathogenesis of Rheumatoid Arthritis, 10.1056/nejmra1004965
  3. FC Breedveld, Arthritis Res Ther, 13, S3 (2011)
  4. Sfikakis Petros P., The First Decade of Biologic TNF Antagonists in Clinical Practice: Lessons Learned, Unresolved Issues and Future Directions, Current Directions in Autoimmunity (2010) ISBN:9783805593830 p.180-210, 10.1159/000289205
  5. Hetland Merete Lund, Christensen Ib Jarle, Tarp Ulrik, Dreyer Lene, Hansen Annette, Hansen Ib Tønder, Kollerup Gina, Linde Louise, Lindegaard Hanne M., Poulsen Uta Engling, Schlemmer Annette, Jensen Dorte Vendelbo, Jensen Signe, Hostenkamp Gisela, ØStergaard Mikkel, , Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: Results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry, 10.1002/art.27227
  6. Russell Anthony S, Quality-of-Life Assessment in Rheumatoid Arthritis : , 10.2165/00019053-200826100-00004
  7. Rubbert-Roth Andrea, Finckh Axel, Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical review, 10.1186/ar2666
  8. van Schouwenburg Pauline A., Rispens Theo, Wolbink Gerrit Jan, Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis, 10.1038/nrrheum.2013.4
  9. Mulleman Denis, Ducourau Emilie, Paintaud Gilles, Ternant David, Watier Hervé, Goupille Philippe, Should anti-TNF-α drug levels and/or anti-drug antibodies be assayed in patients treated for rheumatoid arthritis?, 10.1016/j.jbspin.2011.11.004
  10. Semerano Luca, Assier Eric, Delavallée Laure, Boissier Marie-Christophe, Kinoid of human tumor necrosis factor-alpha for rheumatoid arthritis, 10.1517/14712598.2011.566856
  11. Biton Jérôme, Semerano Luca, Delavallée Laure, Lemeiter Delphine, Laborie Marion, Grouard-Vogel Géraldine, Boissier Marie-Christophe, Bessis Natacha, Interplay between TNF and Regulatory T Cells in a TNF-Driven Murine Model of Arthritis, 10.4049/jimmunol.1003372
  12. Harris J.R, Markl∗ J, Keyhole limpet hemocyanin (KLH): a biomedical review, 10.1016/s0968-4328(99)00036-0
  13. Le Buanec H., Delavallee L., Bessis N., Paturance S., Bizzini B., Gallo R., Zagury D., Boissier M.-C., TNF  kinoid vaccination-induced neutralizing antibodies to TNF  protect mice from autologous TNF -driven chronic and acute inflammation, 10.1073/pnas.0604827103
  14. Hayward Michael D, Jones Beverly K, Saparov Arman, Hain Heather S, Trillat Anne-Cecile, Bunzel Michelle M, Corona Aaron, Li-Wang Bifang, Strenkowski Bryan, Giordano Caroline, Shen Hai, Arcamone Emily, Weidlick Jeffrey, Vilensky Maria, Tugusheva Marina, Felkner Roland H, Campbell William, Rao Yu, Grass David S, Buiakova Olesia, An extensive phenotypic characterization of the hTNFα transgenic mice, 10.1186/1472-6793-7-13
  15. Delavallee L, Le Buanec H, Bessis N, Assier E, Denys A, Bizzini B, Zagury D, Boissier M-C, Early and long-lasting protection from arthritis in tumour necrosis factor   (TNF ) transgenic mice vaccinated against TNF , 10.1136/ard.2007.079137
  16. Delavallée Laure, Semerano Luca, Assier Eric, Vogel Géraldine, Vuagniaux Grégoire, Laborie Marion, Zagury Daniel, Bessis Natacha, Boissier Marie-Christophe, Active immunization to tumor necrosis factor-α is effective in treating chronic established inflammatory disease: a long-term study in a transgenic model of arthritis, 10.1186/ar2897
  17. P Vandepapeliere, Gastroenterology, 140, S (2011)
  18. Arnett Frank C., Edworthy Steven M., Bloch Daniel A., Mcshane Dennis J., Fries James F., Cooper Norman S., Healey Louis A., Kaplan Stephen R., Liang Matthew H., Luthra Harvinder S., Medsger Thomas A., Mitchell Donald M., Neustadt David H., Pinals Robert S., Schaller Jane G., Sharp John T., Wilder Ronald L., Hunder Gene G., The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis, 10.1002/art.1780310302
  19. Flick David A., Gifford George E., Comparison of in vitro cell cytotoxic assays for tumor necrosis factor, 10.1016/0022-1759(84)90147-9
  20. Aletaha Daniel, Nell Valerie PK, Stamm Tanja, Uffmann Martin, Pflugbeil Stephan, Machold Klaus, Smolen Josef S, 10.1186/ar1740
  21. van Gestel Anke M., Haagsma Cees J., van Riel Piet L. C. M., Validation of rheumatoid arthritis improvement criteria that include simplified joint counts, 10.1002/1529-0131(199810)41:10<1845::aid-art17>;2-k
  22. Gaujoux-Viala Cécile, Mouterde Gaël, Baillet Athan, Claudepierre Pascal, Fautrel Bruno, Le Loët Xavier, Maillefert Jean-Francis, Evaluating disease activity in rheumatoid arthritis: Which composite index is best? A systematic literature analysis of studies comparing the psychometric properties of the DAS, DAS28, SDAI and CDAI, 10.1016/j.jbspin.2011.04.008
  23. Lauwerys Bernard R., Hachulla Eric, Spertini François, Lazaro Estibaliz, Jorgensen Christian, Mariette Xavier, Haelterman Edwige, Grouard-Vogel Géraldine, Fanget Bernard, Dhellin Olivier, Vandepapelière Pierre, Houssiau Frédéric A., Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α-kinoid, 10.1002/art.37785
  24. Spohn G., Guler R., Johansen P., Keller I., Jacobs M., Beck M., Rohner F., Bauer M., Dietmeier K., Kundig T. M., Jennings G. T., Brombacher F., Bachmann M. F., A Virus-Like Particle-Based Vaccine Selectively Targeting Soluble TNF-  Protects from Arthritis without Inducing Reactivation of Latent Tuberculosis, 10.4049/jimmunol.178.11.7450
  25. Zuany-Amorim Claudia, Manlius Corinne, Dalum Iben, Jensen Martin R., Gautam Anand, Pay Graham, Mouritsen Søren, Walker Christoph, Induction of TNF-α Autoantibody Production by AutoVac TNF106: A Novel Therapeutic Approach for the Treatment of Allergic Diseases, 10.1159/000076441
  26. Waterston A M, Salway F, Andreakos E, Butler D M, Feldmann M, Coombes R C, TNF autovaccination induces self anti-TNF antibodies and inhibits metastasis in a murine melanoma model, 10.1038/sj.bjc.6601670
  27. Schneerson R., Preparation, characterization, and immunogenicity of Haemophilus influenzae type b polysaccharide-protein conjugates, 10.1084/jem.152.2.361
  28. Saidenberg-Kermanac'h N., Semerano L., Naccache J. M., Brauner M., Falgarone G., Dumont-Fischer D., Guillot X., Valeyre D., Boissier M-C., Screening for latent tuberculosis in anti-TNF-α candidate patients in a high tuberculosis incidence setting, 10.5588/ijtld.12.0111
  29. Semerano L., Biton J., Delavallée L., Duvallet E., Assier E., Bessis N., Bernier E., Dhellin O., Grouard-Vogel G., Boissier M.-C., Protection from articular damage by passive or active anti-tumour necrosis factor (TNF)-α immunotherapy in human TNF-α transgenic mice depends on anti-TNF-α antibody levels : Activeversuspassive anti-TNF-α, 10.1111/cei.12040
  30. Chatzidionysiou K, Askling J, Eriksson J, Kristensen LE, van Vollenhoven R, et al.. (2013) Effectiveness of TNF inhibitor switch in RA: results from the national Swedish register. Ann Rheum Dis. 2014 Jan 15. doi:[]10.1136/annrheumdis-2013-204714. [Epub ahead of print].
  31. FR Spinelli, Clin Exp Rheumatol, 31, 954 (2013)