User menu

Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities.

Bibliographic reference Wannous, Ramez ; Bon, Emeline ; Gillet, Ludovic ; Chamouton, Julie ; Weber, Günther ; et. al. Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities.. In: Pflügers Archiv - European journal of physiology, (2014)
Permanent URL http://hdl.handle.net/2078/154413
  1. Adhikary T, Brandt D T, Kaddatz K, Stockert J, Naruhn S, Meissner W, Finkernagel F, Obert J, Lieber S, Scharfe M, Jarek M, Toth P M, Scheer F, Diederich W E, Reinartz S, Grosse R, Müller-Brüsselbach S, Müller R, Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion, 10.1038/onc.2012.549
  2. Adhikary Till, Kaddatz Kerstin, Finkernagel Florian, Schönbauer Anne, Meissner Wolfgang, Scharfe Maren, Jarek Michael, Blöcker Helmut, Müller-Brüsselbach Sabine, Müller Rolf, Genomewide Analyses Define Different Modes of Transcriptional Regulation by Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ), 10.1371/journal.pone.0016344
  3. Atack T. C., Myers Stroud D., Watanabe H., Yang T., Hall L., Hipkens S. B., Lowe J. S., Leake B., Magnuson M. A., Yang P., Roden D. M., Informatic and Functional Approaches to Identifying a Regulatory Region for the Cardiac Sodium Channel, 10.1161/circresaha.110.235630
  4. BARASCU A, BESSON P, LEFLOCH O, BOUGNOUX P, JOURDAN M, CDK1-cyclin B1 mediates the inhibition of proliferation induced by omega-3 fatty acids in MDA-MB-231 breast cancer cells, 10.1016/j.biocel.2005.08.015
  5. Blanckaert, Docosahexaenoic acid intake decreases proliferation, increases apoptosis and decreases the invasive potential of the human breast carcinoma cell line MDA-MB-231, 10.3892/ijo_00000549
  6. Bligh E. G., Dyer W. J., A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION, 10.1139/o59-099
  7. Bougnoux P, Hajjaji N, Ferrasson M N, Giraudeau B, Couet C, Le Floch O, Improving outcome of chemotherapy of metastatic breast cancer by docosahexaenoic acid: a phase II trial, 10.1038/sj.bjc.6605441
  8. Bougnoux Philippe, Hajjaji Nawale, Maheo Karine, Couet Charles, Chevalier Stephan, Fatty acids and breast cancer: Sensitization to treatments and prevention of metastatic re-growth, 10.1016/j.plipres.2009.08.003
  9. Brackenbury William J., Voltage-gated sodium channels and metastatic disease, 10.4161/chan.21910
  10. Brisson L., Driffort V., Benoist L., Poet M., Counillon L., Antelmi E., Rubino R., Besson P., Labbal F., Chevalier S., Reshkin S. J., Gore J., Roger S., NaV1.5 Na+ channels allosterically regulate the NHE-1 exchanger and promote the activity of breast cancer cell invadopodia, 10.1242/jcs.123901
  11. Brisson L, Gillet L, Calaghan S, Besson P, Le Guennec J-Y, Roger S, Gore J, NaV1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H+ efflux in caveolae, 10.1038/onc.2010.574
  12. Calaghan Sarah, Kozera Lukasz, White Ed, Compartmentalisation of cAMP-dependent signalling by caveolae in the adult cardiac myocyte, 10.1016/j.yjmcc.2008.04.004
  13. Chevalier Stephan, Goupille Caroline, Mahéo Karine, Domingo Isabelle, Dussiau Charles, Renoux Brigitte, Bougnoux Philippe, Papot Sébastien, Dietary docosahexaenoic acid proposed to sensitize breast tumors to locally delivered drug, 10.2217/clp.10.12
  14. Chlebowski Rowan T., Blackburn George L., Thomson Cynthia A., Nixon Daniel W., Shapiro Alice, Hoy M. Katherine, Goodman Marc T., Giuliano Armando E., Karanja Njeri, McAndrew Philomena, Hudis Clifford, Butler John, Merkel Douglas, Kristal Alan, Caan Bette, Michaelson Richard, Vinciguerra Vincent, Del Prete Salvatore, Winkler Marion, Hall Rayna, Simon Michael, Winters Barbara L., Elashoff Robert M., Dietary Fat Reduction and Breast Cancer Outcome: Interim Efficacy Results From the Women's Intervention Nutrition Study, 10.1093/jnci/djj494
  15. Colas Severine, Germain Emmanuelle, Arab Khelifa, Maheo Karine, Goupille Caroline, Bougnoux Philippe, α-Tocopherol Suppresses Mammary Tumor Sensitivity to Anthracyclines in Fish Oil-Fed Rats, 10.1207/s15327914nc5102_8
  16. Colas S�verine, Paon L�naic, Denis Fabrice, Prat Marie, Louisot Pascal, Hoinard Claude, Le Floch Olivier, Ogilvie Gregory, Bougnoux Philippe, Enhanced radiosensitivity of rat autochthonous mammary tumors by dietary docosahexaenoic acid, 10.1002/ijc.11725
  17. Forman B. M., Chen J., Evans R. M., Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors   and  , 10.1073/pnas.94.9.4312
  18. Fraser S. P., Voltage-Gated Sodium Channel Expression and Potentiation of Human Breast Cancer Metastasis, 10.1158/1078-0432.ccr-05-0327
  19. Gillet Ludovic, Roger Sébastien, Besson Pierre, Lecaille Fabien, Gore Jacques, Bougnoux Philippe, Lalmanach Gilles, Le Guennec Jean-Yves, Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells, 10.1074/jbc.m806891200
  20. Gore J, Besson P, Hoinard C, Bougnoux P (1994) Na-W antiporter activity in relation to membrane fatty acid composition and cell proliferation. Am J Physiol 266:110–120
  21. Hajjaji Nawale, Bougnoux Philippe, Selective sensitization of tumors to chemotherapy by marine-derived lipids: A review, 10.1016/j.ctrv.2012.07.001
  22. Hardman WE, Avula CP, Fernandes G, Cameron IL (2001) Three percent dietary fish oil concentrate increased efficacy of doxorubicin against MDA-MB 231 breast cancer xenografts. Clin Cancer Res 7:2041–2049
  23. Im Dong-Soon, Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs, 10.1016/j.plipres.2012.02.003
  24. Isbilen Banu, Fraser Scott P., Djamgoz Mustafa B.A., Docosahexaenoic acid (omega−3) blocks voltage-gated sodium channel activity and migration of MDA-MB-231 human breast cancer cells, 10.1016/j.biocel.2006.06.014
  25. Jiang W., Zhu Z., McGinley J. N., El Bayoumy K., Manni A., Thompson H. J., Identification of a Molecular Signature Underlying Inhibition of Mammary Carcinoma Growth by Dietary N-3 Fatty Acids, 10.1158/0008-5472.can-12-1047
  26. Kumar A. P., Quake A. L., Chang M. K. X., Zhou T., Lim K. S. Y., Singh R., Hewitt R. E., Salto-Tellez M., Pervaiz S., Clement M.-V., Repression of NHE1 Expression by PPAR  Activation Is a Potential New Approach for Specific Inhibition of the Growth of Tumor Cells In vitro and In vivo, 10.1158/0008-5472.can-09-0219
  27. Lim Hyun-Joung, Lee Seahyoung, Park Jin-Hee, Lee Kuy-Sook, Choi Hye-Eun, Chung Kyung-Sook, Lee Hyoung-Hee, Park Hyun-Young, PPARδ agonist L-165041 inhibits rat vascular smooth muscle cell proliferation and migration via inhibition of cell cycle, 10.1016/j.atherosclerosis.2008.05.023
  28. Mahéo Karine, Vibet Sophie, Steghens Jean Paul, Dartigeas Caroline, Lehman Magali, Bougnoux Philippe, Goré Jacques, Differential sensitization of cancer cells to doxorubicin by DHA: A role for lipoperoxidation, 10.1016/j.freeradbiomed.2005.04.023
  29. Mandal Chandi Charan, Ghosh-Choudhury Triparna, Yoneda Toshi, Choudhury Goutam Ghosh, Ghosh-Choudhury Nandini, Fish oil prevents breast cancer cell metastasis to bone, 10.1016/j.bbrc.2010.10.063
  30. Moraes Leonardo A., Piqueras Laura, Bishop-Bailey David, Peroxisome proliferator-activated receptors and inflammation, 10.1016/j.pharmthera.2005.08.007
  31. Onkal Rustem, Djamgoz Mustafa B.A., Molecular pharmacology of voltage-gated sodium channel expression in metastatic disease: Clinical potential of neonatal Nav1.5 in breast cancer, 10.1016/j.ejphar.2009.08.040
  32. Peters JM, Shah YM, Gonzalez FJ (2012) The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention. Nature Rev Cancer 12:181–195. doi: 10.1038/nrc3214
  33. Pignier C., Revenaz C., Rauly-Lestienne I., Cussac D., Delhon A., Gardette J., Grand B., Direct protective effects of poly-unsaturated fatty acids, DHA and EPA, against activation of cardiac late sodium current : A mechanism for ischemia selectivity, 10.1007/s00395-007-0676-x
  34. Roger Sébastien, Rollin Jérôme, Barascu Aurélia, Besson Pierre, Raynal Pierre-Ivan, Iochmann Sophie, Lei Ming, Bougnoux Philippe, Gruel Yves, Le Guennec Jean-Yves, Voltage-gated sodium channels potentiate the invasive capacities of human non-small-cell lung cancer cell lines, 10.1016/j.biocel.2006.12.007
  35. Roger Sébastien, Besson Pierre, Le Guennec Jean-Yves, Involvement of a novel fast inward sodium current in the invasion capacity of a breast cancer cell line, 10.1016/j.bbamem.2003.07.001
  36. Shang Lijuan L., Dudley Samuel C., Tandem Promoters and Developmentally Regulated 5′- and 3′-mRNA Untranslated Regions of the MouseScn5aCardiac Sodium Channel, 10.1074/jbc.m409977200
  37. Shearer Barry G., Steger David J., Way James M., Stanley Thomas B., Lobe David C., Grillot Didier A., Iannone Marie A., Lazar Mitchell A., Willson Timothy M., Billin Andrew N., Identification and Characterization of a Selective Peroxisome Proliferator-Activated Receptor β/δ (NR1C2) Antagonist, 10.1210/me.2007-0190
  38. Stephen Ruth L., Gustafsson Mattias C. U., Jarvis Morag, Tatoud Roger, Marshall Barry R., Knight Deborah, Ehrenborg Ewa, Harris Adrian L., Wolf C. Roland, Palmer Colin N. A., Activation of Peroxisome Proliferator-Activated Receptor δ Stimulates the Proliferation of Human Breast and Prostate Cancer Cell Lines, 10.1158/0008-5472.can-03-2760
  39. Tan N. S., Icre G., Montagner A., Heggeler B. B.-t., Wahli W., Michalik L., The Nuclear Hormone Receptor Peroxisome Proliferator-Activated Receptor  /  Potentiates Cell Chemotactism, Polarization, and Migration, 10.1128/mcb.00436-07
  40. Venkatachalam Gireedhar, Kumar Alan, Yue Loo, Pervaiz Shazib, Clement Marie, Sakharkar Meena, Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of Human, 10.1186/1471-2164-10-s3-s5
  41. Wahli Walter, Michalik Liliane, PPARs at the crossroads of lipid signaling and inflammation, 10.1016/j.tem.2012.05.001
  42. Wannous R, Bon E, Maheo K, Goupille C, Chamouton J, Bougnoux P, Roger S, Besson P, Chevalier S (2013) PPARbeta mRNA expression, reduced by n-3 PUFA diet in mammary tumor, controls breast cancer cell growth. Biochem Biophys Acta 1831:1618–1625. doi: 10.1016/j.bbalip.2013.07.010
  43. Xiao Y.-F., Ke Q., Wang S.-Y., Auktor K., Yang Y., Wang G. K., Morgan J. P., Leaf A., Single point mutations affect fatty acid block of human myocardial sodium channel   subunit Na+ channels, 10.1073/pnas.061003798
  44. Xiao Y.-F., Potent block of inactivation-deficient Na+ channels by n-3 polyunsaturated fatty acids, 10.1152/ajpcell.00296.2005
  45. Xu H.Eric, Lambert Millard H, Montana Valerie G, Parks Derek J, Blanchard Steven G, Brown Peter J, Sternbach Daniel D, Lehmann Jürgen M, Wisely G.Bruce, Willson Timothy M, Kliewer Steven A, Milburn Michael V, Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors, 10.1016/s1097-2765(00)80467-0
  46. Yang Ming, Kozminski David J., Wold Lindsey A., Modak Rohan, Calhoun Jeffrey D., Isom Lori L., Brackenbury William J., Therapeutic potential for phenytoin: targeting Nav1.5 sodium channels to reduce migration and invasion in metastatic breast cancer, 10.1007/s10549-012-2102-9
  47. Yang P, Cloning and initial characterization of the human cardiac sodium channel (SCN5A) promoter, 10.1016/j.cardiores.2003.09.030
  48. Yao P.-L., Morales J. L., Zhu B., Kang B.-H., Gonzalez F. J., Peters J. M., Activation of Peroxisome Proliferator-Activated Receptor- /  (PPAR- / ) Inhibits Human Breast Cancer Cell Line Tumorigenicity, 10.1158/1535-7163.mct-13-0836
  49. Yuan H., Lu J., Xiao J., Upadhyay G., Umans R., Kallakury B., Yin Y., Fant M. E., Kopelovich L., Glazer R. I., PPAR  Induces Estrogen Receptor-Positive Mammary Neoplasia through an Inflammatory and Metabolic Phenotype Linked to mTOR Activation, 10.1158/0008-5472.can-13-0322