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The investigation of acute optic neuritis: a review and proposed protocol

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Petzold, Axel Wattjes, Mike P Costello, Fiona Flores-Rivera, Jose Fraser, Clare L Sindic, Christian [UCL] Plant, Gordon T

Optic neuritis is an inflammatory optic neuropathy that affects many patients with multiple sclerosis (MS) at some point during their disease course. Differentiation of acute episodes of MS-associated optic neuritis from other autoimmune and inflammatory optic neuropathies is vital for treatment choice and further patient management, but is not always straightforward. Over the past decade, a number of new imaging, laboratory and electrophysiological techniques have entered the clinical arena. To date, however, no consensus guidelines have been devised to specify how and when these techniques can be most rationally applied for the diagnostic work-up of patients with acute optic neuritis. In this article, we review the literature and attempt to formulate a consensus for the investigation of patients with acute optic neuritis, both in standard care and in research with relevance to clinical treatment trials. ERRATUM in: Nat Rev Neurol. 2014 Aug;10(8):i

Document type Article de périodique (Journal article) – Synthèse de littérature
Access type Accès restreint
Publication date 2014
Language Anglais
Journal information "Nature Reviews Neurology" - Vol. 10, no.8, p. 447-458 (2014)
Peer reviewed yes
Publisher Nature Publishing Group ((United Kingdom) London)
issn 1759-4758
e-issn 1759-4766
Publication status Publié
Affiliations UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire
UCL - (SLuc) Service de neurologie
MESH Subject Humans ; Magnetic Resonance Imaging ; Medical History Taking ; Optic Neuritis ; Practice Guidelines as Topic ; Tomography, Optical Coherence
Links
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