User menu

A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors.

Bibliographic reference Loriot, Axelle ; Van Tongelen, Aurélie ; Blanco, Jordi ; Klaessens, Simon ; Cannuyer, Julie ; et. al. A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors.. In: Epigenetics, Vol. 9, no. 8, p. 1163-1171 (2014)
Permanent URL http://hdl.handle.net/2078.1/152152
  1. Bird A., DNA methylation patterns and epigenetic memory, 10.1101/gad.947102
  2. Jones Rachel, Worms gang up on bacteria, 10.1038/nrg962
  3. De Smet Charles, Loriot Axelle, DNA Hypomethylation and Activation of Germline-Specific Genes in Cancer, Advances in Experimental Medicine and Biology (2013) ISBN:9781441999665 p.149-166, 10.1007/978-1-4419-9967-2_7
  4. Simpson Andrew J. G., Caballero Otavia L., Jungbluth Achim, Chen Yao-Tseng, Old Lloyd J., Cancer/testis antigens, gametogenesis and cancer, 10.1038/nrc1669
  5. Cannuyer Julie, Loriot Axelle, Parvizi Grégory K., De Smet Charles, Epigenetic Hierarchy within the MAGEA1 Cancer-Germline Gene: Promoter DNA Methylation Dictates Local Histone Modifications, 10.1371/journal.pone.0058743
  6. De Smet Charles, Lurquin Christophe, Lethé Bernard, Martelange Valérie, Boon Thierry, DNA Methylation Is the Primary Silencing Mechanism for a Set of Germ Line- and Tumor-Specific Genes with a CpG-Rich Promoter, 10.1128/mcb.19.11.7327
  7. Croce Carlo M., Causes and consequences of microRNA dysregulation in cancer, 10.1038/nrg2634
  8. Melo Sonia A., Esteller Manel, Dysregulation of microRNAs in cancer: Playing with fire, 10.1016/j.febslet.2010.08.009
  9. Liu Yan, Guo Fengjie, Dai Miao, Wang Di, Tong Yongqing, Huang Jian, Hu Jinyue, Li Guancheng, Gammaaminobutyric Acid A Receptor Alpha 3 Subunit is Overexpressed in Lung Cancer, 10.1007/s12253-008-9128-7
  10. Liu Yan, Gamma-aminobutyric acid promotes human hepatocellular carcinoma growth through overexpressed gamma-aminobutyric acid A receptor α3 subunit, 10.3748/wjg.14.7175
  11. Lu Yan, Lemon William, Liu Peng-Yuan, Yi Yijun, Morrison Carl, Yang Ping, Sun Zhifu, Szoke Janos, Gerald William L, Watson Mark, Govindan Ramaswamy, You Ming, A Gene Expression Signature Predicts Survival of Patients with Stage I Non-Small Cell Lung Cancer, 10.1371/journal.pmed.0030467
  12. Zhang Xiaoxue, Zhang Rong, Zheng Yuanjie, Shen Jianfei, Xiao Dakai, Li Jin, Shi Xiaoshun, Huang Liyan, Tang Hailing, Liu Jun, He Jianxing, Zhang Haibo, Expression of gamma-aminobutyric acid receptors on neoplastic growth and prediction of prognosis in non-small cell lung cancer, 10.1186/1479-5876-11-102
  13. Zhou Weiying, Fong Miranda Y., Min Yongfen, Somlo George, Liu Liang, Palomares Melanie R., Yu Yang, Chow Amy, O’Connor Sean Timothy Francis, Chin Andrew R., Yen Yun, Wang Yafan, Marcusson Eric G., Chu Peiguo, Wu Jun, Wu Xiwei, Li Arthur Xuejun, Li Zhuo, Gao Hanlin, Ren Xiubao, Boldin Mark P., Lin Pengnian Charles, Wang Shizhen Emily, Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis, 10.1016/j.ccr.2014.03.007
  14. Pfeifer Gerd P, Kadam Swati, Jin Seung-Gi, 5-hydroxymethylcytosine and its potential roles in development and cancer, 10.1186/1756-8935-6-10
  15. Ito Shinsuke, D’Alessio Ana C., Taranova Olena V., Hong Kwonho, Sowers Lawrence C., Zhang Yi, Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification, 10.1038/nature09303
  16. Tahiliani M., Koh K. P., Shen Y., Pastor W. A., Bandukwala H., Brudno Y., Agarwal S., Iyer L. M., Liu D. R., Aravind L., Rao A., Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1, 10.1126/science.1170116
  17. Ko Myunggon, Huang Yun, Jankowska Anna M., Pape Utz J., Tahiliani Mamta, Bandukwala Hozefa S., An Jungeun, Lamperti Edward D., Koh Kian Peng, Ganetzky Rebecca, Liu X. Shirley, Aravind L., Agarwal Suneet, Maciejewski Jaroslaw P., Rao Anjana, Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2, 10.1038/nature09586
  18. Lian Christine Guo, Xu Yufei, Ceol Craig, Wu Feizhen, Larson Allison, Dresser Karen, Xu Wenqi, Tan Li, Hu Yeguang, Zhan Qian, Lee Chung-wei, Hu Di, Lian Bill Q., Kleffel Sonja, Yang Yijun, Neiswender James, Khorasani Abraham J., Fang Rui, Lezcano Cecilia, Duncan Lyn M., Scolyer Richard A., Thompson John F., Kakavand Hojabr, Houvras Yariv, Zon Leonard I., Mihm Martin C., Kaiser Ursula B., Schatton Tobias, Woda Bruce A., Murphy George F., Shi Yujiang G., Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma, 10.1016/j.cell.2012.07.033
  19. Yang H, Liu Y, Bai F, Zhang J-Y, Ma S-H, Liu J, Xu Z-D, Zhu H-G, Ling Z-Q, Ye D, Guan K-L, Xiong Y, Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation, 10.1038/onc.2012.67
  20. Figueroa Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., Tallman Martin S., Sun Zhuoxin, Wolniak Kristy, Peeters Justine K., Liu Wei, Choe Sung E., Fantin Valeria R., Paietta Elisabeth, Löwenberg Bob, Licht Jonathan D., Godley Lucy A., Delwel Ruud, Valk Peter J.M., Thompson Craig B., Levine Ross L., Melnick Ari, Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation, 10.1016/j.ccr.2010.11.015
  21. Hsu Chih-Hung, Peng Kai-Lin, Kang Ming-Lun, Chen Yi-Ren, Yang Yu-Chih, Tsai Chin-Hsien, Chu Chi-Shuen, Jeng Yung-Ming, Chen Yen-Ting, Lin Feng-Mao, Huang Hsien-Da, Lu Yun-Yuh, Teng Yu-Ching, Lin Shinn-Tsuen, Lin Ruo-Kai, Tang Fan-Mei, Lee Sung-Bau, Hsu Huan Ming, Yu Jyh-Cherng, Hsiao Pei-Wen, Juan Li-Jung, TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases, 10.1016/j.celrep.2012.08.030
  22. Cheng Jijun, Guo Shangqin, Chen Suning, Mastriano Stephen J., Liu Chaochun, D’Alessio Ana C., Hysolli Eriona, Guo Yanwen, Yao Hong, Megyola Cynthia M., Li Dan, Liu Jun, Pan Wen, Roden Christine A., Zhou Xiao-Ling, Heydari Kartoosh, Chen Jianjun, Park In-Hyun, Ding Ye, Zhang Yi, Lu Jun, An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis, 10.1016/j.celrep.2013.08.050
  23. Song Su Jung, Ito Keisuke, Ala Ugo, Kats Lev, Webster Kaitlyn, Sun Su Ming, Jongen-Lavrencic Mojca, Manova-Todorova Katia, Teruya-Feldstein Julie, Avigan David E., Delwel Ruud, Pandolfi Pier Paolo, The Oncogenic MicroRNA miR-22 Targets the TET2 Tumor Suppressor to Promote Hematopoietic Stem Cell Self-Renewal and Transformation, 10.1016/j.stem.2013.06.003
  24. Song Su Jung, Poliseno Laura, Song Min Sup, Ala Ugo, Webster Kaitlyn, Ng Christopher, Beringer Gary, Brikbak Nicolai J., Yuan Xin, Cantley Lewis C., Richardson Andrea L., Pandolfi Pier Paolo, MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling, 10.1016/j.cell.2013.06.026
  25. Moran-Crusio Kelly, Reavie Linsey, Shih Alan, Abdel-Wahab Omar, Ndiaye-Lobry Delphine, Lobry Camille, Figueroa Maria E., Vasanthakumar Aparna, Patel Jay, Zhao Xinyang, Perna Fabiana, Pandey Suveg, Madzo Jozef, Song Chunxiao, Dai Qing, He Chuan, Ibrahim Sherif, Beran Miloslav, Zavadil Jiri, Nimer Stephen D., Melnick Ari, Godley Lucy A., Aifantis Iannis, Levine Ross L., Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation, 10.1016/j.ccr.2011.06.001
  26. Quivoron Cyril, Couronné Lucile, Della Valle Véronique, Lopez Cécile K., Plo Isabelle, Wagner-Ballon Orianne, Do Cruzeiro Marcio, Delhommeau Francois, Arnulf Bertrand, Stern Marc-Henri, Godley Lucy, Opolon Paule, Tilly Hervé, Solary Eric, Duffourd Yannis, Dessen Philippe, Merle-Beral Hélène, Nguyen-Khac Florence, Fontenay Michaëla, Vainchenker William, Bastard Christian, Mercher Thomas, Bernard Olivier A., TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis, 10.1016/j.ccr.2011.06.003
  27. Zha Ruopeng, Guo Weijie, Zhang Zhenfeng, Qiu Zhaoping, Wang Qifeng, Ding Jie, Huang Shenglin, Chen Taoyang, Gu Jianren, Yao Ming, He Xianghuo, Genome-Wide Screening Identified That miR-134 Acts as a Metastasis Suppressor by Targeting Integrin β1 in Hepatocellular Carcinoma, 10.1371/journal.pone.0087665
  28. Williams Kristine, Christensen Jesper, Helin Kristian, DNA methylation: TET proteins—guardians of CpG islands?, 10.1038/embor.2011.233
  29. Hackett J. A., Sengupta R., Zylicz J. J., Murakami K., Lee C., Down T. A., Surani M. A., Germline DNA Demethylation Dynamics and Imprint Erasure Through 5-Hydroxymethylcytosine, 10.1126/science.1229277
  30. Yamaguchi Shinpei, Shen Li, Liu Yuting, Sendler Damian, Zhang Yi, Role of Tet1 in erasure of genomic imprinting, 10.1038/nature12805
  31. Gjerstorff M. F., Kock K., Nielsen O., Ditzel H. J., MAGE-A1, GAGE and NY-ESO-1 cancer/testis antigen expression during human gonadal development, 10.1093/humrep/del494
  32. Koslowski Michael, Bell Carolin, Seitz Gerhard, Lehr Hans-Anton, Roemer Klaus, Müntefering Horst, Huber Christoph, Sahin Ugur, Türeci Özlem, Frequent Nonrandom Activation of Germ-Line Genes in Human Cancer, 10.1158/0008-5472.can-04-1187
  33. Maatouk D. M., DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages, 10.1242/dev.02500
  34. Jin Seung-Gi, Wu Xiwei, Li Arthur X., Pfeifer Gerd P., Genomic mapping of 5-hydroxymethylcytosine in the human brain, 10.1093/nar/gkr120
  35. Kaas Garrett A., Zhong Chun, Eason Dawn E., Ross Daniel L., Vachhani Raj V., Ming Guo-li, King Jennifer R., Song Hongjun, Sweatt J. David, TET1 Controls CNS 5-Methylcytosine Hydroxylation, Active DNA Demethylation, Gene Transcription, and Memory Formation, 10.1016/j.neuron.2013.08.032
  36. Rudenko Andrii, Dawlaty Meelad M., Seo Jinsoo, Cheng Albert W., Meng Jia, Le Thuc, Faull Kym F., Jaenisch Rudolf, Tsai Li-Huei, Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction, 10.1016/j.neuron.2013.08.003
  37. Loriot Axelle, Parvizi Grégory K., Reister Sven, De Smet Charles, Silencing of cancer-germline genes in human preimplantation embryos: Evidence for active de novo DNA methylation in stem cells, 10.1016/j.bbrc.2011.11.120
  38. Davis LG, Dibner MD, Battey JF. Basic methods in molecular biology. New York: Elsevier, 1986.
  39. De Smet C., Loriot A., Boon T., Promoter-Dependent Mechanism Leading to Selective Hypomethylation within the 5' Region of Gene MAGE-A1 in Tumor Cells, 10.1128/mcb.24.11.4781-4790.2004
  40. De Smet C., De Backer O., Faraoni I., Lurquin C., Brasseur F., Boon T., The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation., 10.1073/pnas.93.14.7149
  41. Hammerman Peter S., Lawrence Michael S., Voet Douglas, Jing Rui, Cibulskis Kristian, Sivachenko Andrey, Stojanov Petar, McKenna Aaron, Lander Eric S., Gabriel Stacey, Getz Gad, Sougnez Carrie, Imielinski Marcin, Helman Elena, Hernandez Bryan, Pho Nam H., Meyerson Matthew, Chu Andy, Chun Hye-Jung E., Mungall Andrew J., Pleasance Erin, Gordon Robertson A., Sipahimalani Payal, Stoll Dominik, Balasundaram Miruna, Birol Inanc, Butterfield Yaron S. N., Chuah Eric, Coope Robin J. N., Corbett Richard, Dhalla Noreen, Guin Ranabir, He An, Hirst Carrie, Hirst Martin, Holt Robert A., Lee Darlene, Li Haiyan I., Mayo Michael, Moore Richard A., Mungall Karen, Ming Nip Ka, Olshen Adam, Schein Jacqueline E., Slobodan Jared R., Tam Angela, Thiessen Nina, Varhol Richard, Zeng Thomas, Zhao Yongjun, Jones Steven J. M., Marra Marco A., Saksena Gordon, Cherniack Andrew D., Schumacher Stephen E., Tabak Barbara, Carter Scott L., Pho Nam H., Nguyen Huy, Onofrio Robert C., Crenshaw Andrew, Ardlie Kristin, Beroukhim Rameen, Winckler Wendy, Hammerman Peter S., Getz Gad, Meyerson Matthew, Protopopov Alexei, Zhang Jianhua, Hadjipanayis Angela, Lee Semin, Xi Ruibin, Yang Lixing, Ren Xiaojia, Zhang Hailei, Shukla Sachet, Chen Peng-Chieh, Haseley Psalm, Lee Eunjung, Chin Lynda, Park Peter J., Kucherlapati Raju, Socci Nicholas D., Liang Yupu, Schultz Nikolaus, Borsu Laetitia, Lash Alex E., Viale Agnes, Sander Chris, Ladanyi Marc, Todd Auman J., Hoadley Katherine A., Wilkerson Matthew D., Shi Yan, Liquori Christina, Meng Shaowu, Li Ling, Turman Yidi J., Topal Michael D., Tan Donghui, Waring Scot, Buda Elizabeth, Walsh Jesse, Jones Corbin D., Mieczkowski Piotr A., Singh Darshan, Wu Junyuan, Gulabani Anisha, Dolina Peter, Bodenheimer Tom, Hoyle Alan P., Simons Janae V., Soloway Matthew G., Mose Lisle E., Jefferys Stuart R., Balu Saianand, O’Connor Brian D., Prins Jan F., Liu Jinze, Chiang Derek Y., Neil Hayes D., Perou Charles M., Cope Leslie, Danilova Ludmila, Weisenberger Daniel J., Maglinte Dennis T., Pan Fei, Van Den Berg David J., Triche Jr Timothy, Herman James G., Baylin Stephen B., Laird Peter W., Getz Gad, Noble Michael, Voet Doug, Saksena Gordon, Gehlenborg Nils, DiCara Daniel, Zhang Jinhua, Zhang Hailei, Wu Chang-Jiun, Yingchun Liu Spring, Lawrence Michael S., Zou Lihua, Sivachenko Andrey, Lin Pei, Stojanov Petar, Jing Rui, Cho Juok, Nazaire Marc-Danie, Robinson Jim, Thorvaldsdottir Helga, Mesirov Jill, Park Peter J., Chin Lynda, Schultz Nikolaus, Sinha Rileen, Ciriello Giovanni, Cerami Ethan, Gross Benjamin, Jacobsen Anders, Gao Jianjiong, Arman Aksoy B., Weinhold Nils, Ramirez Ricardo, Taylor Barry S., Antipin Yevgeniy, Reva Boris, Shen Ronglai, Mo Qianxing, Seshan Venkatraman, Paik Paul K., Ladanyi Marc, Sander Chris, Akbani Rehan, Zhang Nianxiang, Broom Bradley M., Casasent Tod, Unruh Anna, Wakefield Chris, Craig Cason R., Baggerly Keith A., Weinstein John N., Haussler David, Benz Christopher C., Stuart Joshua M., Zhu Jingchun, Szeto Christopher, Scott Gary K., Yau Christina, Ng Sam, Goldstein Ted, Waltman Peter, Sokolov Artem, Ellrott Kyle, Collisson Eric A., Zerbino Daniel, Wilks Christopher, Ma Singer, Craft Brian, Wilkerson Matthew D., Todd Auman J., Hoadley Katherine A., Du Ying, Cabanski Christopher, Walter Vonn, Singh Darshan, Wu Junyuan, Gulabani Anisha, Bodenheimer Tom, Hoyle Alan P., Simons Janae V., Soloway Matthew G., Mose Lisle E., Jefferys Stuart R., Balu Saianand, Marron J. S., Liu Yufeng, Wang Kai, Liu Jinze, Prins Jan F., Neil Hayes D., Perou Charles M., Creighton Chad J., Zhang Yiqun, Travis William D., Rekhtman Natasha, Yi Joanne, Aubry Marie C., Cheney Richard, Dacic Sanja, Flieder Douglas, Funkhouser William, Illei Peter, Myers Jerome, Tsao Ming-Sound, Penny Robert, Mallery David, Shelton Troy, Hatfield Martha, Morris Scott, Yena Peggy, Shelton Candace, Sherman Mark, Paulauskis Joseph, Meyerson Matthew, Baylin Stephen B., Govindan Ramaswamy, Akbani Rehan, Azodo Ijeoma, Beer David, Bose Ron, Byers Lauren A., Carbone David, Chang Li-Wei, Chiang Derek, Chu Andy, Chun Elizabeth, Collisson Eric, Cope Leslie, Creighton Chad J., Danilova Ludmila, Ding Li, Getz Gad, Hammerman Peter S., Neil Hayes D., Hernandez Bryan, Herman James G., Heymach John, Ida Cristiane, Imielinski Marcin, Johnson Bruce, Jurisica Igor, Kaufman Jacob, Kosari Farhad, Kucherlapati Raju, Kwiatkowski David, Ladanyi Marc, Lawrence Michael S., Maher Christopher A., Mungall Andy, Ng Sam, Pao William, Peifer Martin, Penny Robert, Robertson Gordon, Rusch Valerie, Sander Chris, Schultz Nikolaus, Shen Ronglai, Siegfried Jill, Sinha Rileen, Sivachenko Andrey, Sougnez Carrie, Stoll Dominik, Stuart Joshua, Thomas Roman K., Tomaszek Sandra, Tsao Ming-Sound, Travis William D., Vaske Charles, Weinstein John N., Weisenberger Daniel, Wigle Dennis A., Wilkerson Matthew D., Wilks Christopher, Yang Ping, John Zhang Jianjua, Jensen Mark A., Sfeir Robert, Kahn Ari B., Chu Anna L., Kothiyal Prachi, Wang Zhining, Snyder Eric E., Pontius Joan, Pihl Todd D., Ayala Brenda, Backus Mark, Walton Jessica, Baboud Julien, Berton Dominique L., Nicholls Matthew C., Srinivasan Deepak, Raman Rohini, Girshik Stanley, Kigonya Peter A., Alonso Shelley, Sanbhadti Rashmi N., Barletta Sean P., Greene John M., Pot David A., Tsao Ming-Sound, Bandarchi-Chamkhaleh Bizhan, Boyd Jeff, Weaver JoEllen, Wigle Dennis A., Azodo Ijeoma A., Tomaszek Sandra C., Christine Aubry Marie, Ida Christiane M., Yang Ping, Kosari Farhad, Brock Malcolm V., Rogers Kristen, Rutledge Marian, Brown Travis, Lee Beverly, Shin James, Trusty Dante, Dhir Rajiv, Siegfried Jill M., Potapova Olga, Fedosenko Konstantin V., Nemirovich-Danchenko Elena, Rusch Valerie, Zakowski Maureen, Iacocca Mary V., Brown Jennifer, Rabeno Brenda, Czerwinski Christine, Petrelli Nicholas, Fan Zhen, Todaro Nicole, Eckman John, Myers Jerome, Kimryn Rathmell W., Thorne Leigh B., Huang Mei, Boice Lori, Hill Ashley, Penny Robert, Mallery David, Curley Erin, Shelton Candace, Yena Peggy, Morrison Carl, Gaudioso Carmelo, Bartlett John M. S., Kodeeswaran Sugy, Zanke Brent, Sekhon Harman, David Kerstin, Juhl Hartmut, Van Le Xuan, Kohl Bernard, Thorp Richard, Viet Tien Nguyen, Van Bang Nguyen, Sussman Howard, Duc Phu Bui, Hajek Richard, Phi Hung Nguyen, Khan Khurram Z., Muley Thomas, Mills Shaw Kenna R., Sheth Margi, Yang Liming, Buetow Ken, Davidsen Tanja, Demchok John A., Eley Greg, Ferguson Martin, Dillon Laura A. L., Schaefer Carl, Guyer Mark S., Ozenberger Bradley A., Palchik Jacqueline D., Peterson Jane, Sofia Heidi J., Thomson Elizabeth, Hammerman Peter S., Neil Hayes D., Wilkerson Matthew D., Schultz Nikolaus, Bose Ron, Chu Andy, Collisson Eric A., Cope Leslie, Creighton Chad J., Getz Gad, Herman James G., Johnson Bruce E., Kucherlapati Raju, Ladanyi Marc, Maher Christopher A., Robertson Gordon, Sander Chris, Shen Ronglai, Sinha Rileen, Sivachenko Andrey, Thomas Roman K., Travis William D., Tsao Ming-Sound, Weinstein John N., Wigle Dennis A., Baylin Stephen B., Govindan Ramaswamy, Meyerson Matthew, Comprehensive genomic characterization of squamous cell lung cancers, 10.1038/nature11404