Rousseau, Olivier
[UCL]
In order to access easily to five-membered carbocycles, a new methodology was developed. It involves a sulfonium ylide (instead of carbene, commonly used for this reaction) and a electron poor 1,3-diene. Sulfonium ylides are indeed known to be more easily generated and handled than carbenes. This methodology was applied to various 1,3-dienes and ylides. An asymmetric version of this reaction was also successfully carried out, using chiral sulfonium ylides, leading to excellent enantiomeric excesses.
Bibliographic reference |
Rousseau, Olivier. The (4+1) Annulation Reaction between 1,3-Diene and Sulfonium Ylide.Ph.D. Student's Day (Louvain-la-Neuve, 23/05/2014). |
Permanent URL |
http://hdl.handle.net/2078.1/151658 |