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Limited effects of activated protein C on red blood cell deformability.

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Piagnerelli, Michael Njimi, Hassane Coelho, Tatiana Veloso Reggiori, Giulia Castanares Zapatero, Diego [UCL] Vincent, Jean-Louis

Alterations of the microcirculation are common in critically ill patients and persistence of these alterations is associated with poor outcome. Infusion of high doses of activated protein C can ameliorate the microcirculation. Because red blood cells (RBCs) play an essential role in oxygen transport to the tissues, we studied the effects of activated protein C on RBC deformability in septic patients.

Document type Article de périodique (Journal article)
Publication date 2013
Language Anglais
Journal information "Clinical hemorheology and microcirculation" - Vol. 53, no. 4, p. 387-91 (2013)
Peer reviewed yes
issn 1386-0291
Publication status Publié
Affiliations UCL - (SLuc) Service de soins intensifs
UCL - SSS/IREC/MEDA - Pôle de médecine aiguë
MESH Subject Adult ; Erythrocyte Deformability ; Erythrocytes ; Female ; Humans ; Male ; Microcirculation ; Protein C
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Bibliographic reference Piagnerelli, Michael ; Njimi, Hassane ; Coelho, Tatiana Veloso ; Reggiori, Giulia ; Castanares Zapatero, Diego ; et. al. Limited effects of activated protein C on red blood cell deformability.. In: Clinical hemorheology and microcirculation, Vol. 53, no. 4, p. 387-91 (2013)
Permanent URL http://hdl.handle.net/2078.1/137840