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Human umbilical cord matrix stem cells maintain multilineage differentiation abilities and do not transform during long-term culture

Bibliographic reference scheers, Isabelle ; Lombard, Catherine ; Paganelli, Massimiliano ; Campard, David ; Najimi, Mustapha ; et. al. Human umbilical cord matrix stem cells maintain multilineage differentiation abilities and do not transform during long-term culture. In: PloS one, Vol. 8, no. 8, p. e71374 [1-12] (2013)
Permanent URL http://hdl.handle.net/2078.1/136694
  1. Sancho-Bru P, Najimi M, Caruso M, Pauwelyn K, Cantz T, Forbes S, Roskams T, Ott M, Gehling U, Sokal E, Verfaillie C M, Muraca M, Stem and progenitor cells for liver repopulation: can we standardise the process from bench to bedside?, 10.1136/gut.2008.171116
  2. Nussler Andreas, Konig Sarah, Ott Michael, Sokal Etienne, Christ Bruno, Thasler Wolfgang, Brulport Marc, Gabelein Geredn, Schormann Wiebke, Schulze Maren, Ellis Ewa, Kraemer Matthias, Nocken Frank, Fleig Wolfgang, Manns Michael, Strom Steven C., Hengstler Jan G., Present status and perspectives of cell-based therapies for liver diseases, 10.1016/j.jhep.2006.04.002
  3. Sarugaser Rahul, Lickorish David, Baksh Dolores, Hosseini M. Morris, Davies John E., Human Umbilical Cord Perivascular (HUCPV) Cells: A Source of Mesenchymal Progenitors, 10.1634/stemcells.2004-0166
  4. Wang Hwai-Shi, Hung Shih-Chieh, Peng Shu-Tine, Huang Chun-Chieh, Wei Hung-Mu, Guo Yi-Jhih, Fu Yu-Show, Lai Mei-Chun, Chen Chin-Chang, Mesenchymal Stem Cells in the Wharton's Jelly of the Human Umbilical Cord, 10.1634/stemcells.2004-0013
  5. Fu Yu-Show, Shih Yu-Tsung, Cheng Yun-Chih, Min Ming-Yuan, Transformation of human umbilical mesenchymal cells into neurons in vitro, 10.1007/bf02256131
  6. Campard David, Lysy Philippe A., Najimi Mustapha, Sokal Etienne Marc, Native Umbilical Cord Matrix Stem Cells Express Hepatic Markers and Differentiate Into Hepatocyte-like Cells, 10.1053/j.gastro.2007.12.024
  7. I. Scheers, Cell Therapy for the Treatment of Metabolic Liver Disease: An Update on the Umbilical Cord Derived Stem Cells Candidates, 10.2174/1875043501104010048
  8. Weiss Mark L., Anderson Cameron, Medicetty Satish, Seshareddy Kiran B., Weiss Rita J., VanderWerff Irene, Troyer Deryl, McIntosh Kevin R., Immune Properties of Human Umbilical Cord Wharton's Jelly-Derived Cells, 10.1634/stemcells.2007-1028
  9. Scheers I, Maerckx C, Khuu DN, Marcelle S, Decottignies A, et al.. (2012) Adult derived human liver progenitor cells in long term culture maintain appropriate gatekeeper mechanisms against transformation. Cell Transplant.
  10. Sherr Charles J, DePinho Ronald A, Cellular Senescence, 10.1016/s0092-8674(00)00046-5
  11. Miura Masako, Miura Yasuo, Padilla-Nash Hesed M., Molinolo Alfredo A., Fu Baojin, Patel Vyomesh, Seo Byoung-Moo, Sonoyama Wataru, Zheng Jenny J., Baker Carl C., Chen Wanjun, Ried Thomas, Shi Songtao, Accumulated Chromosomal Instability in Murine Bone Marrow Mesenchymal Stem Cells Leads to Malignant Transformation, 10.1634/stemcells.2005-0403
  12. Tolar Jakub, Nauta Alma J., Osborn Mark J., Panoskaltsis Mortari Angela, McElmurry Ron T., Bell Scott, Xia Lily, Zhou Ning, Riddle Megan, Schroeder Tania M., Westendorf Jennifer J., McIvor R. Scott, Hogendoorn Pancras C.W., Szuhai Karoly, Oseth LeAnn, Hirsch Betsy, Yant Stephen R., Kay Mark A., Peister Alexandra, Prockop Darwin J., Fibbe Willem E., Blazar Bruce R., Sarcoma Derived from Cultured Mesenchymal Stem Cells, 10.1634/stemcells.2005-0620
  13. Wang Y., Huso D.L., Harrington J., Kellner J., Jeong D.K., Turney J., McNiece I.K., Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture, 10.1080/14653240500363216
  14. Retraction: Spontaneous Human Adult Stem Cell Transformation, 10.1158/0008-5472.can-10-2451
  15. Torsvik A., Rosland G. V., Svendsen A., Molven A., Immervoll H., McCormack E., Lonning P. E., Primon M., Sobala E., Tonn J.-C., Goldbrunner R., Schichor C., Mysliwietz J., Lah T. T., Motaln H., Knappskog S., Bjerkvig R., Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter, 10.1158/0008-5472.can-10-1305
  16. Shiras Anjali, Chettiar Sivarajan T, Shepal Varsha, Rajendran Ganeshkumar, Prasad G. Rajendra, Shastry Padma, Spontaneous Transformation of Human Adult Nontumorigenic Stem Cells to Cancer Stem Cells Is Driven by Genomic Instability in a Human Model of Glioblastoma, 10.1634/stemcells.2006-0585
  17. Izadpanah R., Kaushal D., Kriedt C., Tsien F., Patel B., Dufour J., Bunnell B. A., Long-term In vitro Expansion Alters the Biology of Adult Mesenchymal Stem Cells, 10.1158/0008-5472.can-07-5272
  18. Fridman A L, Tainsky M A, Critical pathways in cellular senescence and immortalization revealed by gene expression profiling, 10.1038/onc.2008.213
  19. Cho P. S., Messina D. J., Hirsh E. L., Chi N., Goldman S. N., Lo D. P., Harris I. R., Popma S. H., Sachs D. H., Huang C. A., Immunogenicity of umbilical cord tissue derived cells, 10.1182/blood-2007-03-078774
  20. Najimi Mustapha, Khuu Dung Ngoc, Lysy Philippe Antoine, Jazouli Nawal, Abarca Jorge, Sempoux Christine, Sokal Etienne Marc, Adult-Derived Human Liver Mesenchymal-Like Cells as a Potential Progenitor Reservoir of Hepatocytes?, 10.3727/000000007783465154
  21. Suram Anitha, Kaplunov Jessica, Patel Priyanka L, Ruan Haihe, Cerutti Aurora, Boccardi Virginia, Fumagalli Marzia, Di Micco Raffaella, Mirani Neena, Gurung Resham Lal, Hande Manoor Prakash, d‧Adda di Fagagna Fabrizio, Herbig Utz, Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions : Telomere dysfunction limits cancer progression in humans, 10.1038/emboj.2012.132
  22. Bajpai Vivek K., Mistriotis Panagiotis, Andreadis Stelios T., Clonal multipotency and effect of long-term in vitro expansion on differentiation potential of human hair follicle derived mesenchymal stem cells, 10.1016/j.scr.2011.07.003
  23. Itahana Koji, Campisi Judith, Dimri Goberdhan P., Methods to Detect Biomarkers of Cellular Senescence, Methods in Molecular Biology (2007) ISBN:9781588296580 p.21-31, 10.1007/978-1-59745-361-5_3
  24. Jiang Xu-Rong, Jimenez Gretchen, Chang Edwin, Frolkis Maria, Kusler Brenda, Sage Marijke, Beeche Michelle, Bodnar Andrea G., Wahl Geoffrey M., Tlsty Thea D., Chiu Choy-Pik, 10.1038/5056
  25. Tilman G, Loriot A, Van Beneden A, Arnoult N, Londoño-Vallejo J A, De Smet C, Decottignies A, Subtelomeric DNA hypomethylation is not required for telomeric sister chromatid exchanges in ALT cells, 10.1038/onc.2009.23
  26. Dekairelle A.-F., Assessment of the Transcriptional Activity of p53 Improves the Prediction of Recurrence in Superficial Transitional Cell Carcinoma of the Bladder, 10.1158/1078-0432.ccr-05-0140
  27. Waridel F, Estreicher A, Bron L, Flaman J-M, Fontolliet C, Monnier P, Frebourg T, Iggo R, Field cancerisation and polyclonal p53 mutation in the upper aero- digestive tract, 10.1038/sj.onc.1200812
  28. Nakamura T. M., Telomerase Catalytic Subunit Homologs from Fission Yeast and Human, 10.1126/science.277.5328.955
  29. Shaffer SML, Campbell LJ, editor (2009) International System for Human Cytogenetic Nomenclature. Basel: Karger.
  30. Hayflick L., The limited in vitro lifetime of human diploid cell strains, 10.1016/0014-4827(65)90211-9
  31. Wagner Wolfgang, Horn Patrick, Castoldi Mirco, Diehlmann Anke, Bork Simone, Saffrich Rainer, Benes Vladimir, Blake Jonathon, Pfister Stefan, Eckstein Volker, Ho Anthony D., Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process, 10.1371/journal.pone.0002213
  32. Bonab Mandana, Alimoghaddam Kamran, Talebian Fatemeh, Ghaffari Syed, Ghavamzadeh Ardeshir, Nikbin Behrouz, 10.1186/1471-2121-7-14
  33. Finkel Toren, Serrano Manuel, Blasco Maria A., The common biology of cancer and ageing, 10.1038/nature05985
  34. Rubio R., Garcia-Castro J., Gutierrez-Aranda I., Paramio J., Santos M., Catalina P., Leone P. E., Menendez P., Rodriguez R., Deficiency in p53 but not Retinoblastoma Induces the Transformation of Mesenchymal Stem Cells In vitro and Initiates Leiomyosarcoma In vivo, 10.1158/0008-5472.can-09-4640
  35. Armesilla-Diaz Alejandro, Elvira Gema, Silva Augusto, p53 regulates the proliferation, differentiation and spontaneous transformation of mesenchymal stem cells, 10.1016/j.yexcr.2009.08.004
  36. Petitjean A, Achatz M I W, Borresen-Dale A L, Hainaut P, Olivier M, TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes, 10.1038/sj.onc.1210302
  37. Lang Gene A., Iwakuma Tomoo, Suh Young-Ah, Liu Geng, Rao V.Ashutosh, Parant John M., Valentin-Vega Yasmine A., Terzian Tamara, Caldwell Lisa C., Strong Louise C., El-Naggar Adel K., Lozano Guillermina, Gain of Function of a p53 Hot Spot Mutation in a Mouse Model of Li-Fraumeni Syndrome, 10.1016/j.cell.2004.11.006
  38. Olive Kenneth P., Tuveson David A., Ruhe Zachary C., Yin Bob, Willis Nicholas A., Bronson Roderick T., Crowley Denise, Jacks Tyler, Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome, 10.1016/j.cell.2004.11.004
  39. R Brosh, Nat Rev Cancer, 9, 701 (2009)
  40. Eicheler Wolfgang, Zips Daniel, Dörfler Annegret, Grénman Reidar, Baumann Michael, Splicing Mutations in TP53 in Human Squamous Cell Carcinoma Lines Influence Immunohistochemical Detection, 10.1177/002215540205000207
  41. Anzalone Rita, Iacono Melania Lo, Corrao Simona, Magno Francesca, Loria Tiziana, Cappello Francesco, Zummo Giovanni, Farina Felicia, La Rocca Giampiero, New Emerging Potentials for Human Wharton’s Jelly Mesenchymal Stem Cells: Immunological Features and Hepatocyte-Like Differentiative Capacity, 10.1089/scd.2009.0299
  42. Majore Ingrida, Moretti Pierre, Hass Ralf, Kasper Cornelia, Identification of subpopulations in mesenchymal stem cell-like cultures from human umbilical cord, 10.1186/1478-811x-7-6
  43. Karahuseyinoglu Sercin, Cinar Ozgur, Kilic Emine, Kara Fadil, Akay Guvem Gumus, Demiralp Duygu Özel, Tukun Ajlan, Uckan Duygu, Can Alp, Biology of Stem Cells in Human Umbilical Cord Stroma: In Situ and In Vitro Surveys, 10.1634/stemcells.2006-0286
  44. Bernardo M. E., Zaffaroni N., Novara F., Cometa A. M., Avanzini M. A., Moretta A., Montagna D., Maccario R., Villa R., Daidone M. G., Zuffardi O., Locatelli F., Human Bone Marrow Derived Mesenchymal Stem Cells Do Not Undergo Transformation after Long-term In vitro Culture and Do Not Exhibit Telomere Maintenance Mechanisms, 10.1158/0008-5472.can-06-4690
  45. Ben-Porath Ittai, Weinberg Robert A., When cells get stressed: an integrative view of cellular senescence, 10.1172/jci200420663
  46. Banfi Andrea, Muraglia Anita, Dozin Beatrice, Mastrogiacomo Maddalena, Cancedda Ranieri, Quarto Rodolfo, Proliferation kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells, 10.1016/s0301-472x(00)00160-0
  47. Mareschi Katia, Ferrero Ivana, Rustichelli Deborah, Aschero Simona, Gammaitoni Loretta, Aglietta Massimo, Madon Enrico, Fagioli Franca, Expansion of mesenchymal stem cells isolated from pediatric and adult donor bone marrow, 10.1002/jcb.20681
  48. Meza-Zepeda Leonardo A., Noer Agate, Dahl John Arne, Micci Francesca, Myklebost Ola, Collas Philippe, High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence, 10.1111/j.1582-4934.2007.00146.x
  49. Tarte K., Gaillard J., Lataillade J.-J., Fouillard L., Becker M., Mossafa H., Tchirkov A., Rouard H., Henry C., Splingard M., Dulong J., Monnier D., Gourmelon P., Gorin N.-C., Sensebe L., , Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation, 10.1182/blood-2009-05-219907
  50. Rosland G. V., Svendsen A., Torsvik A., Sobala E., McCormack E., Immervoll H., Mysliwietz J., Tonn J.-C., Goldbrunner R., Lonning P. E., Bjerkvig R., Schichor C., Long-term Cultures of Bone Marrow-Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation, 10.1158/0008-5472.can-08-4630
  51. D Rubio, Cancer Res, 65, 3035 (2005)
  52. Hahn William C., Weinberg Robert A., Rules for Making Human Tumor Cells, 10.1056/nejmra021902
  53. GA Ulaner, Cancer Res, 58, 4168 (1998)
  54. Bryan Tracy M., Englezou Anna, Dalla-Pozza Luciano, Dunham Melissa A., Reddel Roger R., Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines, 10.1038/nm1197-1271
  55. Sawada Rumi, Ito Tomomi, Tsuchiya Toshie, Changes in expression of genes related to cell proliferation in human mesenchymal stem cells during in vitro culture in comparison with cancer cells, 10.1007/s10047-006-0338-z
  56. Soucek Thomas, Pusch Oliver, Hengstschläger-Ottnad Elke, Wawra Edgar, Bernaschek Gerhard, Hengstschläger Markus, Expression of the cyclin-dependent kinase inhibitor p16 during the ongoing cell cycle, 10.1016/0014-5793(95)01033-b
  57. SHAY J, A role for both RB and p53 in the regulation of human cellular senescence*1, 10.1016/0014-4827(91)90453-2