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Oral vanadate decreases muscle insulin resistance in obese fa/fa rats.

Bibliographic reference Brichard, Sonia ; Ongemba, Lumbe ; Henquin, Jean-Claude. Oral vanadate decreases muscle insulin resistance in obese fa/fa rats.. In: Diabetologia : clinical and experimental diabetes and metabolism, Vol. 35, no. 6, p. 522-527 (1992)
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  1. Posner BI, Shaver A, Fantus IG (1990) Insulin mimetic agents: vanadium and peroxovanadium compounds. In: Bailey CJ, Flatt PR (eds) New antidiabetic drugs. Smith-Gordon, London, pp 107?118
  2. Shechter Y (1990) Insulin mimetic effects of vanadate. Possible implications for future treatment of diabetes. Diabetes 39: 1?5
  3. Heyliger CE, Tahiliani AG, McNeill JH (1985) Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats. Science 227: 1474?1477
  4. Meyerovitch J, Farfel Z, Sack J, Shechter Y (1987) Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. J Biol Chem 262: 6658?6662
  5. Brichard SM, Okitolonda W, Henquin JC (1988) Long term improvement of glucose homeostasis by vanadate treatment in diabetic rats. Endocrinology 123: 2048?2053
  6. Blondel O, Bailbe D, Portha B (1989) In vivo insulin resistance in streptozotocin-diabetic rats ? evidence for reversal following oral vanadate treatment. Diabetologia 32: 185?190
  7. Brichard SM, Pottier AM, Henquin JC (1989) Long term improvement of glucose homeostasis by vanadate in obese hyperinsulinemic fa/fa rats. Endocrinology 125: 2510?2516
  8. Brichard SM, Bailey CJ, Henquin JC (1990) Marked improvement of glucose homeostasis in diabetic ob/ob mice given oral vanadate. Diabetes 39: 1326?1332
  9. Brichard SM, Ongemba LN, Kolanowski J, Henquin JC (1991) The influence of vanadate on insulin counter-regulatory hormones in obese fa/fa rats. J Endocrinol 131: 185?191
  10. Terrettaz J, Jeanrenaud B (1983) In vivo hepatic and peripheral insulin resistance in genetically obese (fa/fa) rats. Endocrinology 112: 1346?1351
  11. Leturque A, Burnol AF, Ferre P, Girard J (1984) Pregnancy-induced insulin resistance in the rat: assessment by glucose clamp technique. Am J Physiol 246: E25-E31
  12. Cherrington AD, Williams PE, Harris MS (1978) Relationship between the plasma glucose level and glucose uptake in the conscious dog. Metab Clin Exp 27: 787?791
  13. Kergoat M, Portha B (1985) In vivo hepatic and peripheral insulin sensitivity in rats with non-insulin-dependent diabetes induced by streptozotocin: assessment with the insulin-glucose clamp technique. Diabetes 34: 1120?1126
  14. Ferre P, Leturque A, Burnol AF, Penicaud L, Girard J (1985) A method to quantify glucose utilization in vivo in skeletal muscle and white adipose tissue of the anaesthetized rat. Biochem J 228: 103?110
  15. Penicaud L, Hitier Y, Ferre P, Girard J (1989) Hypoglycaemic effect of metformin in genetically obese (fa/fa) rats results from an increased utilization of blood glucose by intestine. Biochem J 262: 881?885
  16. Leturque A, Ferre P, Burnol AF, Kande J, Maulard P, Girard J (1986) Glucose utilization rates and insulin sensitivity in vivo in tissues of virgin and pregnant rats. Diabetes 35: 172?177
  17. Kraegen EW, James DE, Jenkins AB, Chisholm DJ (1985) Dose-response curves for in vivo insulin sensitivity in individual tissues in rats. Am J Physiol 248: E353-E362
  18. Smith SA, Young P, Cawthorne MA (1986) Quantification in vivo of the effects of insulin on glucose utilization in individual tissues of warm and cold acclimated rats. Biochem J 237: 789?795
  19. Sokal RR, Rohlf FJ (1969) Biometry. The principles and practice of statistics in biological research. Freeman, San Francisco, pp 1?776
  20. Verdonck CA, Rizza RA, Gerich JE (1981) Effects of plasma glucose concentration on glucose utilization and glucose clearance in normal man. Diabetes 30: 535?537
  21. Blondel O, Simon J, Chevalier B, Portha B (1990) Impaired insulin action but normal insulin receptor activity in diabetic rat liver: effect of vanadate. Am J Physiol 258: E459-E467
  22. Rossetti L, Laughlin MR (1989) Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle. J Clin Invest 84: 892?899
  23. Zucker LM, Antoniades HN (1972) Insulin and obesity in the Zucker genetically obese rat ?fatty?. Endocrinology 90: 1320?1330
  24. Bray GA (1977) The Zucker-fatty rat: a review. Fed Proc 36: 148?153
  25. Ionescu E, Sauter JF, Jeanrenaud B (1985) Abnormal glucose tolerance in genetically obese (fa/fa) rats. Am J Physiol 248: E500-E506
  26. Rohner-Jeanrenaud F, Proietto J, Ionescu E, Jeanrenaud B (1986) Mechanism of abnormal glucose tolerance of genetically obese fa/fa rats. Diabetes 35: 1350?1355
  27. Lemonnier D, de Gasquet P, Mackay S et al. (1989) Different levels of food restriction have opposite effects on adipocyte cellularity and lipoprotein-lipase activity in obese rats. Diabète Metab 15: 394?402
  28. Penicaud L, Ferre P, Terretaz J et al. (1987) Development of obesity in Zucker rats. Early insulin resistance in muscles but normal sensitivity in white adipose tissue. Diabetes 36: 626?631
  29. Opie L (1984) The heart. Grune and Stratton, Orlando pp 111?135
  30. Paulson DJ, Kopp SJ, Tow JP, Peace DG (1987) Effects of vanadate on in vivo myocardial reactivity to norepinephrine in diabetic rats. J Pharmacol Exp Ther 240: 529?534
  31. Ramanadham S, Mongold JJ, Brownsey RW, Cros GH, McNeill JH (1989) Oral vanadyl sulfate in treatment of diabetes mellitus in rats. Am J Physiol 257: H904-H911
  32. Mongold JJ, Cros GH, Vian L et al. (1990) Toxicological aspects of vanadyl sulphate on diabetic rats: effects on vanadium levels and pancreatic B-cell morphology. Pharmacol Toxicol 67: 192?198
  33. Fantus IG, Ahmad F, Deragon G (1990) Vanadate augments insulin binding and prolongs insulin action in rat adipocytes. Endocrinology 127: 2716?2725