User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Application of MOBILE (Mapping of Oxygen By Imaging Lipids relaxation Enhancement) to Study Variations in Tumor Oxygenation

Primary tabs

Jordan, Bénédicte [UCL] Magat, Julie [UCL] Colliez, Florence [UCL] Ozel, Elif [UCL] Fruytier, Anne-Catherine [UCL] Marchand, Valérie [UCL] Mignion, Lionel [UCL] Gallez, Bernard [UCL]

The aim of the study was to sensitively monitor changes in tumor oxygen using the MOBILE (mapping of oxygen by imaging lipids relaxation enhancement) technique. This method was applied in mammary tumor mouse models on an 11.7T Bruker MRI system. MOBILE was compared with functional imaging R2*, R1 of water and with pO2 measurements (using EPR oximetry and O2-dependent fluorescence quenching measurements). MOBILE was shown to be capable to monitor changes in oxygenation in tumor tissues.

Document type Article de périodique (Journal article)
Access type Accès restreint
Publication date 2013
Language Anglais
Journal information "Advances in Experimental Biology" - Vol. 789, p. 281-288
Peer reviewed yes
issn 1872-2423
Publication status Publié
Affiliation UCL - SSS/LDRI - Louvain Drug Research Institute
Links
Bibliographic reference Jordan, Bénédicte ; Magat, Julie ; Colliez, Florence ; Ozel, Elif ; Fruytier, Anne-Catherine ; et. al. Application of MOBILE (Mapping of Oxygen By Imaging Lipids relaxation Enhancement) to Study Variations in Tumor Oxygenation. In: Advances in Experimental Biology, Vol. 789, p. 281-288
Permanent URL http://hdl.handle.net/2078.1/134652