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Molecular Study of a Hoxa2 Gain-of-Function in Chondrogenesis: A Model of Idiopathic Proportionate Short Stature.

Bibliographic reference Deprez, Pierre M L ; Nichane, Miloud G ; Lengelé, Benoît ; Rezsohazy, René ; Behets Wydemans, Catherine. Molecular Study of a Hoxa2 Gain-of-Function in Chondrogenesis: A Model of Idiopathic Proportionate Short Stature.. In: International journal of molecular sciences, Vol. 14, no. 10, p. 20386-20398 (2013)
Permanent URL http://hdl.handle.net/2078.1/134488
  1. http://www.posna.org/
  2. Oostdijk Wilma, Grote Floor K., de Muinck Keizer-Schrama Sabine M.P.F., Wit Jan M., Diagnostic Approach in Children with Short Stature, 10.1159/000236082
  3. Massip Laurent, Ectors Fabien, Deprez Pierre, Maleki Mehdi, Behets Catherine, Lengelé Benoît, Delahaut Philippe, Picard Jacques, Rezsöhazy René, Expression of Hoxa2 in cells entering chondrogenesis impairs overall cartilage development, 10.1111/j.1432-0436.2006.00132.x
  4. Deprez Pierre Marcel Louis, Nichane Miloud Georges, Rousseaux Pierre, Devogelaer Jean-Pierre, Chappard Daniel, Lengelé Benoît Georges, Rezsöhazy René, Nyssen-Behets Catherine, Postnatal growth defect in mice upon persistent Hoxa2 expression in the chondrogenic cell lineage, 10.1016/j.diff.2011.10.001
  5. Kim Jung-Eun, Transcriptional regulation of bone formation, 10.2741/s138
  6. Marie Pierre J., Transcription factors controlling osteoblastogenesis, 10.1016/j.abb.2008.02.030
  7. Eames B. Frank, De La Fuente Luis, Helms Jill A., Molecular ontogeny of the skeleton, 10.1002/bdrc.10016
  8. Cancedda, Int. J. Dev. Biol, 44, 707 (2000)
  9. Lefebvre Véronique, Smits Patrick, Transcriptional control of chondrocyte fate and differentiation, 10.1002/bdrc.20048
  10. Rodrigo I., Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome, 10.1242/dev.00240
  11. Church V., Wnt regulation of chondrocyte differentiation, 10.1242/jcs.00152
  12. Jiang Yang Zi, Qi Yi Ying, Zou Xiao Hui, Wang Lin-Lin, Ouyang Hong-Wei, Comparison the Effects of BMP-4 and BMP-7 on Articular Cartilage Repair with Bone Marrow Mesenchymal Stem Cells, IFMBE Proceedings ISBN:9783540928409 p.1285-1288, 10.1007/978-3-540-92841-6_316
  13. Monsoro-Burq A. H., Bontoux M., Teillet M. A., Le Douarin N. M., Heterogeneity in the development of the vertebra., 10.1073/pnas.91.22.10435
  14. Monsoro-Burq, Development, 122, 3607 (1996)
  15. Zeng L., Shh establishes an Nkx3.2/Sox9 autoregulatory loop that is maintained by BMP signals to induce somitic chondrogenesis, 10.1101/gad.1008002
  16. Minina, Development, 128, 4523 (2001)
  17. Yoon B. S., Ovchinnikov D. A., Yoshii I., Mishina Y., Behringer R. R., Lyons K. M., Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo, 10.1073/pnas.0500031102
  18. Yang Y., Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation, 10.1242/dev.00324
  19. Yoon B. S., Pogue R., Ovchinnikov D. A., Yoshii I., Mishina Y., Behringer R. R., Lyons K. M., BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways, 10.1242/dev.02680
  20. Komori Toshihisa, Regulation of skeletal development by the Runx family of transcription factors, 10.1002/jcb.20420
  21. Amano Katsuhiko, Ichida Fumitaka, Sugita Atsushi, Hata Kenji, Wada Masahiro, Takigawa Yoko, Nakanishi Masako, Kogo Mikihiko, Nishimura Riko, Yoneda Toshiyuki, Msx2 Stimulates Chondrocyte Maturation by Controlling Ihh Expression, 10.1074/jbc.m803681200
  22. Kempf Hervé, Ionescu Andreia, Udager Aaron M., Lassar Andrew B., Prochondrogenic signals induce a competence for Runx2 to activate hypertrophic chondrocyte gene expression, 10.1002/dvdy.21205
  23. Yamashita Satoshi, Andoh Masataka, Ueno-Kudoh Hiroe, Sato Tempei, Miyaki Shigeru, Asahara Hiroshi, Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes, 10.1016/j.yexcr.2009.03.008
  24. Ovchinnikov Dmitry A., Deng Jian Min, Ogunrinu George, Behringer Richard R., Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice, 10.1002/(sici)1526-968x(200002)26:2<145::aid-gene14>3.0.co;2-c
  25. Kanzler, Development, 125, 2587 (1998)
  26. Lettice L. A., Purdie L. A., Carlson G. J., Kilanowski F., Dorin J., Hill R. E., The mouse bagpipe gene controls development of axial skeleton, skull, and spleen, 10.1073/pnas.96.17.9695
  27. Jena Nilamani, Martı́n-Seisdedos Carmen, McCue Peter, Croce Carlo M., BMP7 Null Mutation in Mice: Developmental Defects in Skeleton, Kidney, and Eye, 10.1006/excr.1996.3411
  28. Tribioli, Development, 126, 5699 (1999)
  29. Yeh Lee-Chuan C., Mallein-Gerin Frederic, Lee John C., Differential effects of osteogenic protein-1 (BMP-7) on gene expression of BMP and GDF family members during differentiation of the mouse MC615 chondrocyte cells, 10.1002/jcp.10094
  30. Yoon Byeong S., Lyons Karen M., Multiple functions of BMPs in chondrogenesis, 10.1002/jcb.20211
  31. Bendall A.J., Abate-Shen C., Roles for Msx and Dlx homeoproteins in vertebrate development, 10.1016/s0378-1119(00)00081-0
  32. Otto Florian, Lübbert Michael, Stock Michael, Upstream and downstream targets of RUNX proteins, 10.1002/jcb.10491
  33. Hatakeyama Yuji, Tuan Rocky S., Shum Lillian, Distinct functions of BMP4 and GDF5 in the regulation of chondrogenesis, 10.1002/jcb.20019
  34. Shen Bojiang, Bhargav Divya, Wei Aiqun, Williams Lisa A, Tao Helen, Ma David D F, Diwan Ashish D, BMP-13 Emerges as a Potential Inhibitor of Bone Formation, 10.7150/ijbs.5.192
  35. Marsell Richard, Einhorn Thomas A., The role of endogenous bone morphogenetic proteins in normal skeletal repair, 10.1016/s0020-1383(09)70003-8
  36. Meech R., The homeobox transcription factor Barx2 regulates chondrogenesis during limb development, 10.1242/dev.01811
  37. Kronenberg Henry M., Developmental regulation of the growth plate, 10.1038/nature01657
  38. Akiyama Haruhiko, Control of chondrogenesis by the transcription factor Sox9, 10.3109/s10165-008-0048-x
  39. Oh Chun-do, Maity Sankar N., Lu Jing-Fang, Zhang Jiexin, Liang Shoudan, Coustry Francoise, de Crombrugghe Benoit, Yasuda Hideyo, Identification of SOX9 Interaction Sites in the Genome of Chondrocytes, 10.1371/journal.pone.0010113
  40. Bradley Elizabeth W., Drissi M. Hicham, WNT5A Regulates Chondrocyte Differentiation through Differential Use of the CaN/NFAT and IKK/NF-κB Pathways, 10.1210/me.2010-0037
  41. Lanske Beate, Amling Michael, Neff Lynn, Guiducci Jennifer, Baron Roland, Kronenberg Henry M., Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development, 10.1172/jci6629
  42. Karaplis A C, Luz A, Glowacki J, Bronson R T, Tybulewicz V L, Kronenberg H M, Mulligan R C, Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene., 10.1101/gad.8.3.277
  43. Ducy P., Starbuck M., Priemel M., Shen J., Pinero G., Geoffroy V., Amling M., Karsenty G., A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development, 10.1101/gad.13.8.1025
  44. Yamaguchi, Development, 126, 1211 (1999)
  45. Akazawa Hiroshi, Komuro Issei, Sugitani Yoshinobu, Yazaki Yoshio, Nagai Ryozo, Noda Tetsuo, Targeted disruption of the homeobox transcription factor Bapx1 results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation, 10.1046/j.1365-2443.2000.00339.x
  46. Ovchinnikov Dmitry A., Selever Jennifer, Wang Ying, Chen You-Tzung, Mishina Yuji, Martin James F., Behringer Richard R., BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning, 10.1016/j.ydbio.2006.03.013
  47. St-Jacques B., Hammerschmidt M., McMahon A. P., Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation, 10.1101/gad.13.16.2072
  48. Akiyama H., Interactions between Sox9 and  -catenin control chondrocyte differentiation, 10.1101/gad.1171104
  49. Peters H., Neubuser A., Kratochwil K., Balling R., Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities, 10.1101/gad.12.17.2735
  50. Smits Patrick, Li Ping, Mandel Jennifer, Zhang Zhaoping, Deng Jian Ming, Behringer Richard R, de Crombrugghe Benoit, Lefebvre Véronique, The Transcription Factors L-Sox5 and Sox6 Are Essential for Cartilage Formation, 10.1016/s1534-5807(01)00003-x
  51. Peters, Development, 126, 5399 (1999)
  52. Smits Patrick, Dy Peter, Mitra Srijeet, Lefebvre Véronique, Sox5andSox6are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate, 10.1083/jcb.200312045
  53. Abzhanov A., Rodda S. J., McMahon A. P., Tabin C. J., Regulation of skeletogenic differentiation in cranial dermal bone, 10.1242/dev.002709
  54. Franz-Odendaal, Front. Biosci, 17, 3734 (2012)
  55. Hall Brian K., Development of the clavicles in birds and mammals, 10.1002/1097-010x(20010215)289:3<153::aid-jez1>3.0.co;2-o
  56. Huang Lih-Fen, Fukai Naomi, Selby Paul B., Olsen Bjorn R., Mundlos Stefan, Mouse clavicular development: Analysis of wild-type and cleidocranial dysplasia mutant mice, 10.1002/(sici)1097-0177(199709)210:1<33::aid-aja4>3.0.co;2-2
  57. Kramer Jan, Klinger Matthias, Kruse Charli, Faza Marius, Hargus Gunnar, Rohwedel Jürgen, Ultrastructural analysis of mouse embryonic stem cell-derived chondrocytes, 10.1007/s00429-005-0020-x
  58. Buxton, J. Bone Joint Surg. Am, 83, S23 (2001)
  59. Cho Tae-Joon, Gerstenfeld Louis C., Einhorn Thomas A., Differential Temporal Expression of Members of the Transforming Growth Factor β Superfamily During Murine Fracture Healing, 10.1359/jbmr.2002.17.3.513
  60. Dehne Tilo, Schenk Rita, Perka Carsten, Morawietz Lars, Pruss Axel, Sittinger Michael, Kaps Christian, Ringe Jochen, Gene expression profiling of primary human articular chondrocytes in high-density micromasses reveals patterns of recovery, maintenance, re- and dedifferentiation, 10.1016/j.gene.2010.04.006
  61. Akiyama H., The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6, 10.1101/gad.1017802
  62. Tu Xiaolin, Joeng Kyu Sang, Long Fanxin, Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation, 10.1016/j.ydbio.2011.11.013
  63. Yueh Y. G., Gardner D. P., Kappen C., Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8, 10.1073/pnas.95.17.9956
  64. Kruger Claudia, Kappen Claudia, Expression of Cartilage Developmental Genes in Hoxc8- and Hoxd4-Transgenic Mice, 10.1371/journal.pone.0008978
  65. Gérard A.-C., Many M.-C., Daumerie C., Costagliola S., Miot F., DeVijlder J. J. M., Colin I. M., Denef J.-F., Structural Changes in the Angiofollicular Units between Active and Hypofunctioning Follicles Align with Differences in the Epithelial Expression of Newly Discovered Proteins Involved in Iodine Transport and Organification, 10.1210/jcem.87.3.8278
  66. Fisher, Acta Orthop. Scand. Suppl, 266, 61 (1995)
  67. Bancroft, 766 (1996)