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Extended voice-sparing surgery in selected pyriform sinus carcinoma: Techniques and outcomes

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Hamoir, Marc [UCL] Fievez, Juliette [UCL] Schmitz, Sandra [UCL] Velasco, Dorris [UCL] Lengelé, Benoît [UCL]

BACKGROUND: Organ-preservation approaches are frequently favored in the treatment of advanced pyriform sinus carcinoma. In selected cases, use of free flaps allows voice-sparing surgery. METHODS:Thirteen patients underwent conservative extended laryngopharyngectomy. In 11 patients, the resection included the supraglottic larynx, whereas the whole hemilarynx was resected in 2. Reconstruction was achieved with a radial forearm free flap with the palmaris longus tendon. In hemilarynx resection, a costal graft was also used. Functional results were assessed by nasofibroscopy and swallowing videofluoroscopic tests. RESULTS: At 12 months, no patient was gastrostomy dependent, whereas 1 patient remained tracheostomy dependent. At 1, 3, and 5 years, the locoregional control was 100%, 100%, and 83%; overall survival was 69.4%, 46.3%, and 30.8%; and disease-specific survival was 81.2%, 54.5%, and 36.4%, respectively. CONCLUSIONS: In selected patients, extended conservative laryngopharyngectomy challenges the oncologic results of organ-preservation protocols and allows a good quality of life.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès libre
Publication date 2013
Language Anglais
Journal information "Head & Neck : journal for the sciences and specialities of the head and neck" - Vol. 35, no. 10, p. 1482-1489 (2013)
Peer reviewed yes
Publisher John Wiley And Sons ((United States) New York, NY)
issn 1043-3074
e-issn 1097-0347
Publication status Publié
Affiliations UCL - SSS/IREC/MORF - Pôle de Morphologie
UCL - (SLuc) Service de chirurgie plastique
UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie
UCL - (SLuc) Service d'oto-rhino-laryngologie
Keywords Hypopharynx cancer ; Pyriform sinus carcinoma ; Conservative surgery ; Free flap reconstruction
Links
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Bibliographic reference Hamoir, Marc ; Fievez, Juliette ; Schmitz, Sandra ; Velasco, Dorris ; Lengelé, Benoît. Extended voice-sparing surgery in selected pyriform sinus carcinoma: Techniques and outcomes. In: Head & Neck : journal for the sciences and specialities of the head and neck, Vol. 35, no. 10, p. 1482-1489 (2013)
Permanent URL http://hdl.handle.net/2078.1/132834