User menu

The atherogenic dyslipidemia ratio [log(TG)/HDL-C] is associated with residual vascular risk, beta-cell function loss and microangiopathy in type 2 diabetes females

Bibliographic reference Hermans, Michel ; Ahn, Sylvie A ; Rousseau, Michel. The atherogenic dyslipidemia ratio [log(TG)/HDL-C] is associated with residual vascular risk, beta-cell function loss and microangiopathy in type 2 diabetes females. In: Lipids in Health and Disease, Vol. 11, p. 132 [1-8] (2012)
Permanent URL
  1. Brunzell John D., Davidson Michael, Furberg Curt D., Goldberg Ronald B., Howard Barbara V., Stein James H., Witztum Joseph L., Lipoprotein Management in Patients With Cardiometabolic Risk, 10.1016/j.jacc.2008.02.034
  2. McAlister Finlay A., Quan Hude, Fong Andrew, Jin Yan, Cujec Bibiana, Johnson David, Effect of Invasive Coronary Revascularization in Acute Myocardial Infarction on Subsequent Death Rate and Frequency of Chronic Heart Failure, 10.1016/j.amjcard.2008.02.089
  3. Hermans Michel P, Ahn Sylvie A, Rousseau Michel F, log(TG)/HDL-C is related to both residual cardiometabolic risk and β-cell function loss in type 2 diabetes males, 10.1186/1475-2840-9-88
  4. Fruchart J.C., Sacks F.M., Hermans M.P., , Implications of the ACCORD Lipid study: perspective from the Residual Risk Reduction Initiative (R3i), 10.1185/03007995.2010.489341
  5. Hermans Michel P, Non-invited Review: Prevention of microvascular diabetic complications by fenofibrate: lessons from FIELD and ACCORD, 10.1177/1479164111407783
  6. Mosca Lori, Appel Lawrence J, Benjamin Emelia J, Berra Kathy, Chandra-Strobos Nisha, Fabunmi Rosalind P, Grady Deborah, Haan Constance K, Hayes Sharonne N, Judelson Debra R, Keenan Nora L, McBride Patrick, Oparil Suzanne, Ouyang Pamela, Oz Mehmet C, Mendelsohn Michael E, Pasternak Richard C, Pinn Vivian W, Robertson Rose Marie, Schenck-Gustafsson Karin, Sila Cathy A, Smith Sidney C, Sopko George, Taylor Anne L, Walsh Brian W, Wenger Nanette K, Williams Christine L, Evidence-based guidelines for cardiovascular disease prevention in women 11The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest.This statement was approved by the American Heart Association Science Advisory and Coordinating Committee and by the American College of Cardiology Foundation in December 2003. This document is available on the World Wide Web sites of the American College of Cardiology ( and the American Heart Association ( A single reprint is available by calling 800-242-8721 (US only) or writing the American Heart Association, Public Information, 7272 Greenville Ave, Dallas, TX 75231-4596. Ask for reprint No. 71–0276. To purchase additional reprints: up to 999 copies, call 800-611-6083 (US only) or fax 413-665-2671; 1000 or more copies, call 410-528-4121, fax 410-528-4264, or e-mail To make photocopies for personal or educational use, call the Copyright Clearance Center, 978-750-8400.(J Am Coll Cardiol 2004;43:900–21)The online-only Data Supplement is available at, 10.1016/j.jacc.2004.02.001
  7. Legato Marianne J., Gelzer Andrea, Goland Robin, Ebner Susana A., Rajan Sabitha, Villagra Victor, Kosowski Mark, Gender-specific care of the patient with diabetes: Review and recommendations, 10.1016/s1550-8579(06)80202-0
  8. Stevens R. J., Coleman R. L., Adler A. I., Stratton I. M., Matthews D. R., Holman R. R., Risk Factors for Myocardial Infarction Case Fatality and Stroke Case Fatality in Type 2 Diabetes: UKPDS 66, 10.2337/diacare.27.1.201
  9. Alberti K.G.M.M., Eckel R. H., Grundy S. M., Zimmet P. Z., Cleeman J. I., Donato K. A., Fruchart J.-C., James W. P. T., Loria C. M., Smith S. C., Harmonizing the Metabolic Syndrome: A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity, 10.1161/circulationaha.109.192644
  10. Kyle Ursula G, Morabia Alfredo, Schutz Yves, Pichard Claude, Sedentarism affects body fat mass index and fat-free mass index in adults aged 18 to 98 years, 10.1016/j.nut.2003.11.019
  11. Burkhauser Richard V., Cawley John, Beyond BMI: The value of more accurate measures of fatness and obesity in social science research, 10.1016/j.jhealeco.2007.05.005
  12. Levy J. C., Matthews D. R., Hermans M. P., Correct Homeostasis Model Assessment (HOMA) Evaluation Uses the Computer Program, 10.2337/diacare.21.12.2191
  13. Hermans M. P., Levy J. C., Morris R. J., Turner R. C., Comparison of insulin sensitivity tests across a range of glucose tolerance from normal to diabetes, 10.1007/s001250051215
  14. Hermans M. P., Levy J. C., Morris R. J., Turner R. C., Comparison of tests of beta-cell function across a range of glucose tolerance from normal to diabetes, 10.2337/diabetes.48.9.1779
  15. Hermans M.P., Ahn S.A., Rousseau M.F., Statin therapy and cataract in type 2 diabetes, 10.1016/j.diabet.2010.09.005
  16. Dobiás̆ová Milada, Frohlich Jiri, The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate inapob-lipoprotein-depleted plasma (FERHDL), 10.1016/s0009-9120(01)00263-6
  17. Kannel William B., Vasan Ramachandran S., Keyes Michelle J., Sullivan Lisa M., Robins Sander J., Usefulness of the Triglyceride–High-Density Lipoprotein Versus the Cholesterol–High-Density Lipoprotein Ratio for Predicting Insulin Resistance and Cardiometabolic Risk (from the Framingham Offspring Cohort), 10.1016/j.amjcard.2007.09.109
  18. Bittner Vera, Johnson B. Delia, Zineh Issam, Rogers William J., Vido Diane, Marroquin Oscar C., Bairey-Merz C. Noel, Sopko George, The triglyceride/high-density lipoprotein cholesterol ratio predicts all-cause mortality in women with suspected myocardial ischemia, 10.1016/j.ahj.2008.11.014
  19. Cordero Alberto, Andrés Eva, Ordoñez Beatriz, León Montserrat, Laclaustra Martín, Grima Alberto, Luengo Emilio, Moreno José, Bes María, Pascual Isaac, Civeira Fernando, Pocoví Miguel, Alegría Eduardo, Casasnovas José A., Usefulness of Triglycerides-to–High-Density Lipoprotein Cholesterol Ratio for Predicting the First Coronary Event in Men, 10.1016/j.amjcard.2009.07.008
  20. Kim-Dorner Su-Jong, Deuster Patricia A., Zeno Stacey A., Remaley Alan T., Poth Merrily, Should triglycerides and the triglycerides to high-density lipoprotein cholesterol ratio be used as surrogates for insulin resistance?, 10.1016/j.metabol.2009.07.027
  21. Hermans Michel P, Sacks Frank M, Ahn Sylvie A, Rousseau Michel F, Non-HDL-cholesterol as valid surrogate to apolipoprotein B100 measurement in diabetes: Discriminant Ratio and unbiased equivalence, 10.1186/1475-2840-10-20
  22. Levy J., Atkinson A.B., Bell P.M., McCance D.R., Hadden D.R., Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in Type 2 diabetes mellitus: the 10-year follow-up of the Belfast Diet Study, 10.1002/(sici)1096-9136(199804)15:4<290::aid-dia570>;2-m
  23. Turner Robert C., Glycemic Control With Diet, Sulfonylurea, Metformin, or Insulin in Patients With Type 2 Diabetes MellitusProgressive Requirement for Multiple Therapies (UKPDS 49), 10.1001/jama.281.21.2005
  24. Sorrentino S. A., Besler C., Rohrer L., Meyer M., Heinrich K., Bahlmann F. H., Mueller M., Horvath T., Doerries C., Heinemann M., Flemmer S., Markowski A., Manes C., Bahr M. J., Haller H., von Eckardstein A., Drexler H., Landmesser U., Endothelial-Vasoprotective Effects of High-Density Lipoprotein Are Impaired in Patients With Type 2 Diabetes Mellitus but Are Improved After Extended-Release Niacin Therapy, 10.1161/circulationaha.108.836346
  25. Li Chaoyang, Ford Earl S, Meng Yuan-Xiang, Mokdad Ali H, Reaven Gerald M, Does the association of the triglyceride to high-density lipoprotein cholesterol ratio with fasting serum insulin differ by race/ethnicity?, 10.1186/1475-2840-7-4