User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Focal myopathy associated with chronic intramuscular injection of piritramide

Primary tabs

Van den Bergh, Peter [UCL] Guettat, Lamia [UCL] Vande Berg, Bruno [UCL] Martin, Jean-Jacques

We report a patient in whom chronic intramuscular piritramide led to a focal fibrotic myopathy. Since piritramide myotoxicity has never been reported, we have studied its effect on rat skeletal muscle. Chronic intramuscular piritramide led to fibrous connective tissue replacement of rat skeletal muscle, similar to that found in the patient's muscle. Although the pathogenetic mechanism of piritramide myopathy is unclear, we caution against prolonged intramuscular use of piritramide to prevent this potentially debilitating adverse effect.

Document type Article de périodique (Journal article) – Article de recherche – Case Reports, Journal Article
Access type Accès restreint
Publication date 1997
Language Anglais
Journal information "Muscle & Nerve" - Vol. 20, no. 12, p. 1598-600 (1997)
Peer reviewed yes
Publisher JohnWiley & Sons, Inc. (Hoboken)
issn 0148-639X
e-issn 1097-4598
Publication status Publié
Affiliations UCL - MD/RAIM - Département de radiologie et d'imagerie médicale
UCL - (SLuc) Service de radiologie
UCL - MD/NOPS - Département de neurologie et de psychiatrie
UCL - (SLuc) Service de neurologie
MESH Subject Adult ; Analgesics, Opioid - administration & dosage - adverse effects ; Animals ; Connective Tissue - pathology ; Humans ; Injections, Intramuscular ; Male ; Muscles - drug effects - pathology ; Muscular Diseases - chemically induced - pathology ; Pirinitramide - administration & dosage - adverse effects ; Rats ; Time Factors
Keywords Piritramide ; Narcotic analgesics ; Intrmuscular injection ; Focal myopathy
Links
  1. Aberfeld D. C., Bienenstock H., Shapiro M. S., Namba T., Grob D., Diffuse Myopathy Related to Meperidine Addiction in a Mother and Daughter, 10.1001/archneur.1968.00480040050004
  2. Adams Elaine M., Fibrous Myopathy in Association With Pentazocine, 10.1001/archinte.1983.00350110193042
  3. De Schepper A M, Degryse H R, Imaging findings in a patient with pentazocine-induced myopathy., 10.2214/ajr.154.2.2105028
  4. Gibb W R G, Shaw I C, Myoglobinuria Due to Heroin Abuse, 10.1177/014107688507801015
  5. Gunn, J Bone Joint Surg Br, 46, 492 (1964)
  6. Levin Barry E., Iatrogenic Muscle Fibrosis : Arm Levitation as an Initial Sign, 10.1001/jama.1975.03260190049025
  7. Lloyd-Roberts, J Bone Joint Surg Br, 46, 498 (1964)
  8. Louis Elan D., Bodner Russ A., Challenor Yasoma B., Brust John C. M., Focal myopathy induced by chronic intramuscular heroin injection, 10.1002/mus.880170513
  9. Malek, Ann Chir Infant, 7, 85 (1966)
  10. : Pentazocine-induced neuromuscular syndromes: clinical, immunological and histopathological studies in two cases. Acta Neuropathol 1981; suppl VII: 246-248.
  11. Mastaglia F L, Gardner-Medwin D, Hudgson P, Muscle fibrosis and contractures in a pethidine addict., 10.1136/bmj.4.5786.532
  12. : Pentazocine-blocked myogenesis in human foetal muscle cultures. Acta Neuropathol 1981; suppl VII: 310-312.
  13. Norman Margaret G., Temple Anthony R., Murphy Jerome V., Infantile Quadriceps-Femoris Contracture Resulting from Intramuscular Injections, 10.1056/nejm197004232821708
  14. Oh Shin Joong, Pentazocine-lnduced Fibrous Myopathy, 10.1001/jama.1975.03240150033018
  15. Oh, Ala J Med Sci, 14, 64 (1977)
  16. Parks Dean L., Cutaneous Complications of Pentazocine Injections, 10.1001/archderm.1971.04000210005002
  17. Pena J., Aranda C., Luque E., Vaamonde R., Heroin-induced myopathy in rat skeletal muscle, 10.1007/bf00294224
  18. Richter Ralph W., Acute Myoglobinuria Associated With Heroin Addiction, 10.1001/jama.1971.03180330048009
  19. Todd J. V., Intramuscular Injections, 10.1136/bmj.2.5263.1362
  20. Kemp K.von, Herregodts P., Duynslaegcr L., Deleu D., Bruyland M., Cham B., Muscular Fibrosis Due to Chronic Intramuscular Administration of Narcotic Analgesics, 10.1080/17843286.1989.11718047
Bibliographic reference Van den Bergh, Peter ; Guettat, Lamia ; Vande Berg, Bruno ; Martin, Jean-Jacques. Focal myopathy associated with chronic intramuscular injection of piritramide. In: Muscle & Nerve, Vol. 20, no. 12, p. 1598-600 (1997)
Permanent URL http://hdl.handle.net/2078.1/13144