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Top-Down Inhibitory Control Exerted by the Medial Frontal Cortex during Action Selection under Conflict.

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Duque, Julie [UCL] Olivier, Etienne [UCL] Rushworth, Matthew [University of Oxford]

Top-down control is critical to select goal-directed actions in changeable environments, particularly when several conflicting options compete for selection. In humans, this control system is thought to involve an inhibitory mechanism that suppresses the motor representation of unwanted responses to favor selection of the most appropriate action. Here, we aimed to evaluate the role of a region of the medial frontal cortex, the pre-SMA, in this form of inhibition by using a double coil TMS protocol combining repetitive TMS (rTMS) over the pre-SMA and a single-pulse TMS over the primary motor cortex (M1) during a visuomotor task that required participants to choose between a left or right button press according to an imperative cue. M1 stimulation allowed us to assess changes in motor excitability related to selected and nonselected (unwanted) actions, whereas rTMS was used to produce transient disruption of pre-SMA functioning. We found that when rTMS was applied over pre-SMA, inhibition of the nonselected movement representation was reduced. Importantly, this effect was only observed when the imperative cue produced a substantial amount of competition between the response alternatives. These results are consistent with previous studies pointing to a role of pre-SMA in competition resolution. In addition, our findings indicate that this function of pre-SMA involves the control of inhibitory influences directed at unwanted action representations.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2013
Language Anglais
Journal information "Journal of Cognitive Neuroscience" - Vol. 25, no. 10, p. 1634-48 (2013)
Peer reviewed yes
Publisher M I T Press ((United States) Cambridge)
issn 0898-929X
e-issn 1530-8898
Publication status Publié
Affiliation UCL - SSS/IONS/COSY - Systems & cognitive Neuroscience
Links
  1. Aron Adam R., The Neural Basis of Inhibition in Cognitive Control, 10.1177/1073858407299288
  2. Aron A. R., Cortical and Subcortical Contributions to Stop Signal Response Inhibition: Role of the Subthalamic Nucleus, 10.1523/jneurosci.4682-05.2006
  3. Brown Scott, Heathcote Andrew, A Ballistic Model of Choice Response Time., 10.1037/0033-295x.112.1.117
  4. Brown Scott, Heathcote Andrew, Practice Increases the Efficiency of Evidence Accumulation in Perceptual Choice., 10.1037/0096-1523.31.2.289
  5. Brown Scott D., Heathcote Andrew, The simplest complete model of choice response time: Linear ballistic accumulation, 10.1016/j.cogpsych.2007.12.002
  6. Burle Borı́s, Vidal Franck, Tandonnet Christophe, Hasbroucq Thierry, Physiological evidence for response inhibition in choice reaction time tasks, 10.1016/j.bandc.2004.06.004
  7. Cai W., George J. S., Verbruggen F., Chambers C. D., Aron A. R., The role of the right presupplementary motor area in stopping action: two studies with event-related transcranial magnetic stimulation, 10.1152/jn.00132.2012
  8. CHEN C, MUGGLETON N, TZENG O, HUNG D, JUAN C, Control of prepotent responses by the superior medial frontal cortex, 10.1016/j.neuroimage.2008.09.005
  9. Chen Robert, Hallett Mark, The Time Course of Changes in Motor Cortex Excitability Associated with Voluntary Movement, 10.1017/s0317167100000196
  10. Chen Robert, Yaseen Zaneb, Cohen Leonardo G., Hallett Mark, Time course of corticospinal excitability in reaction time and self-paced movements, 10.1002/ana.410440306
  11. Cisek Paul, Making decisions through a distributed consensus, 10.1016/j.conb.2012.05.007
  12. Cisek Paul, Kalaska John F., Neural Mechanisms for Interacting with a World Full of Action Choices, 10.1146/annurev.neuro.051508.135409
  13. Coles Michael G. H., Gratton Gabriele, Bashore Theodore R., Eriksen Charles W., Donchin Emanuel, A psychophysiological investigation of the continuous flow model of human information processing., 10.1037/0096-1523.11.5.529
  14. Davare M., Dissociating the Role of Ventral and Dorsal Premotor Cortex in Precision Grasping, 10.1523/jneurosci.3386-05.2006
  15. Davare M, Duque J, Vandermeeren Y, Thonnard J-L, Olivier E, Role of the Ipsilateral Primary Motor Cortex in Controlling the Timing of Hand Muscle Recruitment, 10.1093/cercor/bhj152
  16. Davranche Karen, Tandonnet Christophe, Burle Boris, Meynier Chloé, Vidal Franck, Hasbroucq Thierry, The dual nature of time preparation: neural activation and suppression revealed by transcranial magnetic stimulation of the motor cortex, 10.1111/j.1460-9568.2007.05588.x
  17. Della Sala Sergio, Marchetti Clelia, Spinnler Hans, Right-sided anarchic (alien) hand: A longitudinal study, 10.1016/0028-3932(91)90081-i
  18. Doya Kenji, Shadlen Michael N, Decision making, 10.1016/j.conb.2012.10.003
  19. Duque Julie, Davare Marco, Delaunay Ludovic, Jacob Benvenuto, Saur Ralf, Hummel Friedhelm, Hermoye Laurent, Rossion Bruno, Olivier Etienne, Monitoring Coordination during Bimanual Movements: Where Is the Mastermind?, 10.1162/jocn.2009.21213
  20. Duque J., Ivry R. B., Role of Corticospinal Suppression during Motor Preparation, 10.1093/cercor/bhn230
  21. Duque J., Labruna L., Verset S., Olivier E., Ivry R. B., Dissociating the Role of Prefrontal and Premotor Cortices in Controlling Inhibitory Mechanisms during Motor Preparation, 10.1523/jneurosci.4299-12.2012
  22. Duque J., Lew D., Mazzocchio R., Olivier E., Ivry R. B., Evidence for Two Concurrent Inhibitory Mechanisms during Response Preparation, 10.1523/jneurosci.5722-09.2010
  23. Duque J., Kinematically Specific Interhemispheric Inhibition Operating in the Process of Generation of a Voluntary Movement, 10.1093/cercor/bhh160
  24. Duque J, Mazzocchio R, Stefan K, Hummel F, Olivier E, Cohen L. G., Memory Formation in the Motor Cortex Ipsilateral to a Training Hand, 10.1093/cercor/bhm173
  25. Duque Julie, Murase Nagako, Celnik Pablo, Hummel Friedhelm, Harris-Love Michelle, Mazzocchio Riccardo, Olivier Etienne, Cohen Leonardo G., Intermanual Differences in Movement-related Interhemispheric Inhibition, 10.1162/jocn.2007.19.2.204
  26. Duque Julie, Vandermeeren Yves, Lejeune Thierry M., Thonnard Jean-Louis, Smith Allan M., Olivier Etienne, Paradoxical effect of digital anaesthesia on force and corticospinal excitability : , 10.1097/00001756-200502280-00011
  27. Feinberg T. E., Schindler R. J., Flanagan N. G., Haber L. D., Two alien hand syndromes, 10.1212/wnl.42.1.19
  28. Goghari Vina M., MacDonald Angus W., The neural basis of cognitive control: Response selection and inhibition, 10.1016/j.bandc.2009.04.004
  29. Grinband Jack, Savitskaya Judith, Wager Tor D., Teichert Tobias, Ferrera Vincent P., Hirsch Joy, The dorsal medial frontal cortex is sensitive to time on task, not response conflict or error likelihood, 10.1016/j.neuroimage.2010.12.027
  30. Heekeren Hauke R., Marrett Sean, Ungerleider Leslie G., The neural systems that mediate human perceptual decision making, 10.1038/nrn2374
  31. Hikosaka Okihide, Isoda Masaki, Switching from automatic to controlled behavior: cortico-basal ganglia mechanisms, 10.1016/j.tics.2010.01.006
  32. Hofer Sabine, Frahm Jens, Topography of the human corpus callosum revisited—Comprehensive fiber tractography using diffusion tensor magnetic resonance imaging, 10.1016/j.neuroimage.2006.05.044
  33. Hsu Tzu-Yu, Tseng Lin-Yuan, Yu Jia-Xin, Kuo Wen-Jui, Hung Daisy L., Tzeng Ovid J.L., Walsh Vincent, Muggleton Neil G., Juan Chi-Hung, Modulating inhibitory control with direct current stimulation of the superior medial frontal cortex, 10.1016/j.neuroimage.2011.03.059
  34. Isoda Masaki, Hikosaka Okihide, Switching from automatic to controlled action by monkey medial frontal cortex, 10.1038/nn1830
  35. Isoda Masaki, Hikosaka Okihide, Cortico-basal ganglia mechanisms for overcoming innate, habitual and motivational behaviors : Behavioral switching network, 10.1111/j.1460-9568.2011.07698.x
  36. Klein P.-A., Olivier E., Duque J., Influence of Reward on Corticospinal Excitability during Movement Preparation, 10.1523/jneurosci.1701-12.2012
  37. Leocani Letizia, Cohen Leonardo G., Wassermann Eric M., Ikoma Katsunori, Hallett Mark, Human corticospinal excitability evaluated with transcranial magnetic stimulation during different reaction time paradigms, 10.1093/brain/123.6.1161
  38. Liston Conor, Matalon Shanna, Hare Todd A., Davidson Matthew C., Casey B.J., Anterior Cingulate and Posterior Parietal Cortices Are Sensitive to Dissociable Forms of Conflict in a Task-Switching Paradigm, 10.1016/j.neuron.2006.04.015
  39. Marconi B., Genovesio A., Giannetti S., Molinari M., Caminiti R., Callosal connections of dorso-lateral premotor cortex, 10.1046/j.1460-9568.2003.02807.x
  40. Mars R. B., Klein M. C., Neubert F.-X., Olivier E., Buch E. R., Boorman E. D., Rushworth M. F. S., Short-Latency Influence of Medial Frontal Cortex on Primary Motor Cortex during Action Selection under Conflict, 10.1523/jneurosci.1396-09.2009
  41. McMillan Steven, Ivry Richard B., Byblow Winston D., Corticomotor excitability during a choice-hand reaction time task, 10.1007/s00221-005-0331-4
  42. Meckler Cédric, Allain Sonia, Carbonnell Laurence, Hasbroucq Thierry, Burle Boris, Vidal Franck, Motor inhibition and response expectancy: A Laplacian ERP study, 10.1016/j.biopsycho.2010.08.011
  43. Meynier Chloe, Burle Boris, Possamaï Camille-Aime, Vidal Franck, Hasbroucq Thierry, Neural inhibition and interhemispheric connections in two-choice reaction time: A Laplacian ERP study, 10.1111/j.1469-8986.2009.00818.x
  44. Mock J. R., NeuroReport, 22, 830 (2011)
  45. Munakata Yuko, Herd Seth A., Chatham Christopher H., Depue Brendan E., Banich Marie T., O’Reilly Randall C., A unified framework for inhibitory control, 10.1016/j.tics.2011.07.011
  46. Munoz Douglas P., Everling Stefan, Look away: the anti-saccade task and the voluntary control of eye movement, 10.1038/nrn1345
  47. Nachev Parashkev, Kennard Christopher, Husain Masud, Functional role of the supplementary and pre-supplementary motor areas, 10.1038/nrn2478
  48. Nachev Parashkev, Rees Geraint, Parton Andrew, Kennard Christopher, Husain Masud, Volition and Conflict in Human Medial Frontal Cortex, 10.1016/j.cub.2005.01.006
  49. Nachev Parashkev, Wydell Henrietta, O’Neill Kevin, Husain Masud, Kennard Christopher, The role of the pre-supplementary motor area in the control of action, 10.1016/j.neuroimage.2007.03.034
  50. Neubert F.-X., Mars R. B., Buch E. R., Olivier E., Rushworth M. F. S., Cortical and subcortical interactions during action reprogramming and their related white matter pathways, 10.1073/pnas.1000674107
  51. Nigbur Roland, Cohen Michael X, Ridderinkhof K. Richard, Stürmer Birgit, Theta Dynamics Reveal Domain-specific Control over Stimulus and Response Conflict, 10.1162/jocn_a_00128
  52. Noirhomme Q., Ferrant M., Vandermeeren Y., Olivier E., Macq B., Cuisenaire O., Registration and Real-Time Visualization of Transcranial Magnetic Stimulation With 3-D MR Images, 10.1109/tbme.2004.834266
  53. Obeso Jose A., Olanow Warren, Deep brain stimulation for Parkinson's disease: Thinking about the long-term in the short-term, 10.1002/mds.24036
  54. Oldfield R.C., The assessment and analysis of handedness: The Edinburgh inventory, 10.1016/0028-3932(71)90067-4
  55. Oliveira Flavio T. P., Diedrichsen Jörn, Verstynen Timothy, Duque Julie, Ivry Richard B., Transcranial magnetic stimulation of posterior parietal cortex affects decisions of hand choice, 10.1073/pnas.1006223107
  56. Picard Nathalie, Strick Peter L., Motor Areas of the Medial Wall: A Review of Their Location and Functional Activation, 10.1093/cercor/6.3.342
  57. Ridderinkhof K. Richard, van den Wildenberg Wery P.M., Segalowitz Sidney J., Carter Cameron S., Neurocognitive mechanisms of cognitive control: The role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning, 10.1016/j.bandc.2004.09.016
  58. Rossi Simone, Hallett Mark, Rossini Paolo M., Pascual-Leone Alvaro, Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research, 10.1016/j.clinph.2009.08.016
  59. Rushworth M. F., Journal of Neurophysiology, 87, 2577 (2002)
  60. Rushworth Matthew F. S., Krams Michael, Passingham Richard E., The Attentional Role of the Left Parietal Cortex: The Distinct Lateralization and Localization of Motor Attention in the Human Brain, 10.1162/089892901750363244
  61. Schall Jeffrey D, Godlove David C, Current advances and pressing problems in studies of stopping, 10.1016/j.conb.2012.06.002
  62. Seeley T. D., Visscher P. K., Schlegel T., Hogan P. M., Franks N. R., Marshall J. A. R., Stop Signals Provide Cross Inhibition in Collective Decision-Making by Honeybee Swarms, 10.1126/science.1210361
  63. Stuphorn V., Brown J. W., Schall J. D., Role of Supplementary Eye Field in Saccade Initiation: Executive, Not Direct, Control, 10.1152/jn.00221.2009
  64. Stuphorn Veit, Schall Jeffrey D, Executive control of countermanding saccades by the supplementary eye field, 10.1038/nn1714
  65. Swann Nicole C., Cai Weidong, Conner Christopher R., Pieters Thomas A., Claffey Michael P., George Jobi S., Aron Adam R., Tandon Nitin, Roles for the pre-supplementary motor area and the right inferior frontal gyrus in stopping action: Electrophysiological responses and functional and structural connectivity, 10.1016/j.neuroimage.2011.09.049
  66. Tandonnet Christophe, Garry Michael I., Summers Jeffery J., Selective suppression of the incorrect response implementation in choice behavior assessed by transcranial magnetic stimulation : Suppression of incorrect response implementation, 10.1111/j.1469-8986.2010.01121.x
  67. Taylor P. C. J., Nobre A. C., Rushworth M. F. S., Subsecond Changes in Top Down Control Exerted by Human Medial Frontal Cortex during Conflict and Action Selection: A Combined Transcranial Magnetic Stimulation Electroencephalography Study, 10.1523/jneurosci.2877-07.2007
  68. Usher Marius, McClelland James L., Loss Aversion and Inhibition in Dynamical Models of Multialternative Choice., 10.1037/0033-295x.111.3.757
  69. van de Laar Maria C., van den Wildenberg Wery P.M., van Boxtel Geert J.M., Huizenga Hilde M., van der Molen Maurits W., Lifespan changes in motor activation and inhibition during choice reactions: A Laplacian ERP study, 10.1016/j.biopsycho.2011.11.005
  70. van den Wildenberg Wery P.M., Wylie Scott A., Forstmann Birte U., Burle Borís, Hasbroucq Thierry, Ridderinkhof K. Richard, To Head or to Heed? Beyond the Surface of Selective Action Inhibition: A Review, 10.3389/fnhum.2010.00222
  71. van Gaal S., Ridderinkhof K. R., Scholte H. S., Lamme V. A. F., Unconscious Activation of the Prefrontal No-Go Network, 10.1523/jneurosci.2992-09.2010
  72. Wijnen Jasper G., Ridderinkhof K. Richard, Response inhibition in motor and oculomotor conflict tasks: Different mechanisms, different dynamics?, 10.1016/j.bandc.2006.09.003
Bibliographic reference Duque, Julie ; Olivier, Etienne ; Rushworth, Matthew. Top-Down Inhibitory Control Exerted by the Medial Frontal Cortex during Action Selection under Conflict.. In: Journal of Cognitive Neuroscience, Vol. 25, no. 10, p. 1634-48 (2013)
Permanent URL http://hdl.handle.net/2078.1/131259