User menu

Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures.

Bibliographic reference Couturier, Julien ; Paccalin, M ; Morel, M ; Terro, F ; Milin, S ; et. al. Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures.. In: Journal of Neuroinflammation, Vol. 8, no. Online, p. 72 (2011)
Permanent URL http://hdl.handle.net/2078.1/127309
  1. BONIFATI D, KISHORE U, Role of complement in neurodegeneration and neuroinflammation, 10.1016/j.molimm.2006.03.007
  2. McGeer P.L., Akiyama H., Itagaki S., McGeer E.G., Activation of the classical complement pathway in brain tissue of Alzheimer patients, 10.1016/0304-3940(89)90843-4
  3. McGEER P. L., Inflammation and the Degenerative Diseases of Aging, 10.1196/annals.1332.007
  4. Webster S, Lue L.-F, Brachova L, Tenner A.J, McGeer P.L, Terai K, Walker D.G, Bradt B, Cooper N.R, Rogers J, Molecular and Cellular Characterization of the Membrane Attack Complex, C5b-9, in Alzheimer’s Disease, 10.1016/s0197-4580(97)00042-0
  5. Rogers J., Cooper N. R., Webster S., Schultz J., McGeer P. L., Styren S. D., Civin W. H., Brachova L., Bradt B., Ward P., Complement activation by beta-amyloid in Alzheimer disease., 10.1073/pnas.89.21.10016
  6. HENEKA M, OBANION M, Inflammatory processes in Alzheimer's disease, 10.1016/j.jneuroim.2006.11.017
  7. Akiyama H, Inflammation and Alzheimer's disease, 10.1016/s0197-4580(00)00124-x
  8. Salminen Antero, Ojala Johanna, Kauppinen Anu, Kaarniranta Kai, Suuronen Tiina, Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors, 10.1016/j.pneurobio.2009.01.001
  9. Bakshi Pancham, Margenthaler Elaina, Laporte Vincent, Crawford Fiona, Mullan Michael, Novel Role of CXCR2 in Regulation of γ-Secretase Activity, 10.1021/cb800167a
  10. Liao Yung-Feng, Wang Bo-Jeng, Cheng Hui-Ting, Kuo Lan-Hsin, Wolfe Michael S., Tumor Necrosis Factor-α, Interleukin-1β, and Interferon-γ Stimulate γ-Secretase-mediated Cleavage of Amyloid Precursor Protein through a JNK-dependent MAPK Pathway, 10.1074/jbc.m402034200
  11. Sheng Jin G., Jones Richard A., Zhou Xue Q., McGinness John M., Van Eldik Linda J., Mrak Robert E., Griffin W.Sue T., Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: potential significance for tau protein phosphorylation, 10.1016/s0197-0186(01)00041-9
  12. Griffin W Sue T, Liu Ling, Li Yuekui, Mrak Robert E, Barger Steven W, 10.1186/1742-2094-3-5
  13. Braida Daniela, Sacerdote Paola, Panerai Alberto E, Bianchi Mauro, Aloisi Anna Maria, Iosuè Stefania, Sala Mariaelvina, Cognitive function in young and adult IL (interleukin)-6 deficient mice, 10.1016/j.bbr.2003.12.018
  14. Tancredi Virginia, D'Arcangelo Giovanna, Grassi Francesca, Tarroni Paolo, Palmieri Gabriella, Santoni Angela, Eusebi Fabrizio, Tumor necrosis factor alters synaptic transmission in rat hippocampal slices, 10.1016/0304-3940(92)90071-e
  15. Lee Kang Soo, Chung Ji Hyung, Choi Tae Kyou, Suh Shin Young, Oh Byoung Hoon, Hong Chang Hyung, Peripheral Cytokines and Chemokines in Alzheimer’s Disease, 10.1159/000245156
  16. Rojo Leonel E., Fernández Jorge A., Maccioni Andrea A., Jimenez José M., Maccioni Ricardo B., Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease, 10.1016/j.arcmed.2007.10.001
  17. Tobinick Edward, Tumour Necrosis Factor Modulation for Treatment of Alzheimerʼs Disease : Rationale and Current Evidence, 10.2165/11310810-000000000-00000
  18. Yamamoto Yumi, Gaynor Richard B., Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer, 10.1172/jci11914
  19. Zhang X., Luhrs K.J., Ryff K.A., Malik W.T., Driscoll M.J., Culver B., Suppression of nuclear factor kappa B ameliorates astrogliosis but not amyloid burden in APPswe/PS1dE9 mice, 10.1016/j.neuroscience.2009.03.010
  20. Peel A, Activation of the cell stress kinase PKR in Alzheimer's disease and human amyloid precursor protein transgenic mice, 10.1016/s0969-9961(03)00086-x
  21. Page G., Rioux Bilan A., Ingrand S., Lafay-Chebassier C., Pain S., Perault Pochat M.C., Bouras C., Bayer T., Hugon J., Activated double-stranded RNA-dependent protein kinase and neuronal death in models of Alzheimer’s disease, 10.1016/j.neuroscience.2006.01.047
  22. Paccalin Marc, Pain-Barc Stéphanie, Pluchon Claudette, Paul Chloé, Besson Marie-Noelle, Carret-Rebillat Anne-Sophie, Rioux-Bilan Agnès, Gil Roger, Hugon Jacques, Activated mTOR and PKR Kinases in Lymphocytes Correlate with Memory and Cognitive Decline in Alzheimer’s Disease, 10.1159/000095562
  23. Morel Milena, Couturier Julien, Lafay-Chebassier Claire, Paccalin Marc, Page Guylène, PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease, 10.1111/j.1582-4934.2009.00849.x
  24. Chang Raymond C. C., Wong Ada K. Y., Ng Ho-Keung, Hugon Jacques, Phosphorylation of eukaryotic initiation factor-2α (eIF2α) is associated with neuronal degeneration in Alzheimerʼs disease : , 10.1097/00001756-200212200-00011
  25. Zamanian-Daryoush M., Mogensen T. H., DiDonato J. A., Williams B. R. G., NF-kappa B Activation by Double-Stranded-RNA-Activated Protein Kinase (PKR) Is Mediated through NF-kappa B-Inducing Kinase and Ikappa B Kinase, 10.1128/mcb.20.4.1278-1290.2000
  26. Kumar A., Haque J., Lacoste J., Hiscott J., Williams B. R., Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B., 10.1073/pnas.91.14.6288
  27. Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal B B, Genetic deletion of PKR abrogates TNF-induced activation of IκBα kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation, 10.1038/sj.onc.1209906
  28. Jammi Narasimham V., Whitby Landon R., Beal Peter A., Small molecule inhibitors of the RNA-dependent protein kinase, 10.1016/s0006-291x(03)01318-4
  29. Morel Milena, Couturier Julien, Pontcharraud Raymond, Gil Roger, Fauconneau Bernard, Paccalin Marc, Page Guylène, Evidence of molecular links between PKR and mTOR signalling pathways in Aβ neurotoxicity: Role of p53, Redd1 and TSC2, 10.1016/j.nbd.2009.07.004
  30. Frank Matthew G., Wieseler-Frank Julie L., Watkins Linda R., Maier Steven F., Rapid isolation of highly enriched and quiescent microglia from adult rat hippocampus: Immunophenotypic and functional characteristics, 10.1016/j.jneumeth.2005.06.026
  31. Lawson L.J., Perry V.H., Dri P., Gordon S., Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain, 10.1016/0306-4522(90)90229-w
  32. Suen Ka-Chun, Yu Man-Shan, So Kwok-Fai, Chang Raymond Chuen-Chung, Hugon Jacques, Upstream Signaling Pathways Leading to the Activation of Double-stranded RNA-dependent Serine/Threonine Protein Kinase in β-Amyloid Peptide Neurotoxicity, 10.1074/jbc.m306503200
  33. Couturier Julien, Morel Milena, Pontcharraud Raymond, Gontier Virginie, Fauconneau Bernard, Paccalin Marc, Page Guylène, Interaction of Double-stranded RNA-dependent Protein Kinase (PKR) with the Death Receptor Signaling Pathway in Amyloid β (Aβ)-treated Cells and in APPSLPS1 Knock-in Mice, 10.1074/jbc.m109.041954
  34. Viatour Patrick, Merville Marie-Paule, Bours Vincent, Chariot Alain, Phosphorylation of NF-κB and IκB proteins: implications in cancer and inflammation, 10.1016/j.tibs.2004.11.009
  35. Buss Holger, Dörrie Anneke, Schmitz M. Lienhard, Frank Ronald, Livingstone Mark, Resch Klaus, Kracht Michael, Phosphorylation of Serine 468 by GSK-3β Negatively Regulates Basal p65 NF-κB Activity, 10.1074/jbc.c400442200
  36. Sakurai Hiroaki, Chiba Hiroaki, Miyoshi Hidetaka, Sugita Takahisa, Toriumi Wataru, IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain, 10.1074/jbc.274.43.30353
  37. Kumar A., Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappa B, 10.1093/emboj/16.2.406
  38. Bonnet M. C., Weil R., Dam E., Hovanessian A. G., Meurs E. F., PKR Stimulates NF-kappa B Irrespective of Its Kinase Function by Interacting with the Ikappa B Kinase Complex, 10.1128/mcb.20.13.4532-4542.2000
  39. Meda Lucia, Cassatella Marco A., Szendrei Gyorgyi I., Otvos Laszlo, Baron Pierluigi, Villalba Martin, Ferrari Davide, Rossi Filippo, Activation of microglial cells by β-amyloid protein and interferon-γ, 10.1038/374647a0
  40. Liu Man-Hai, Lin Yu-Shan, Sheu Shiow-Yunn, Sun Jui-Sheng, Anti-inflammatory effects of daidzein on primary astroglial cell culture, 10.1179/147683009x423274
  41. Floden A. M., beta-Amyloid Stimulates Murine Postnatal and Adult Microglia Cultures in a Unique Manner, 10.1523/jneurosci.4822-05.2006
  42. Franciosi Sonia, Choi Hyun B., Kim Seung U., McLarnon James G., IL-8 enhancement of amyloid-beta (Aβ1-42)-induced expression and production of pro-inflammatory cytokines and COX-2 in cultured human microglia, 10.1016/j.jneuroim.2004.10.006
  43. McGeer Patrick L., Rogers Joseph, McGeer Edith G., Neuroimmune Mechanisms in Alzheimer Disease Pathogenesis : , 10.1097/00002093-199408030-00001
  44. Minghetti L., Carnevale D., Simone R., Microglia-Neuron Interaction in Inflammatory and Degenerative Diseases: Role of Cholinergic and Noradrenergic Systems, 10.2174/187152707783399193
  45. Hatton Glenn I, Dynamic neuronal–glial interactions: an overview 20 years later, 10.1016/j.peptides.2003.12.001
  46. Näslund Jan, Correlation Between Elevated Levels of Amyloid β-Peptide in the Brain and Cognitive Decline, 10.1001/jama.283.12.1571
  47. Farina Cinthia, Aloisi Francesca, Meinl Edgar, Astrocytes are active players in cerebral innate immunity, 10.1016/j.it.2007.01.005
  48. Ivins Kathryn J., Bui Elizabeth T.N., Cotman Carl W., β-Amyloid Induces Local Neurite Degeneration in Cultured Hippocampal Neurons: Evidence for Neuritic Apoptosis, 10.1006/nbdi.1998.0228
  49. Chen Jennifer, Zhou Yungui, Mueller-Steiner Sarah, Chen Lin-Feng, Kwon Hakju, Yi Saili, Mucke Lennart, Gan Li, SIRT1 Protects against Microglia-dependent Amyloid-β Toxicity through Inhibiting NF-κB Signaling, 10.1074/jbc.m509329200
  50. Desai A., Konda V. R., Darland G., Austin M., Prabhu K. S., Bland J. S., Carroll B. J., Tripp M. L., META060 inhibits multiple kinases in the NF-κB pathway and suppresses LPS – mediated inflammation in vitro and ex vivo, 10.1007/s00011-008-8162-y
  51. Gruol D. L., Nelson T. E., Physiological and pathological roles of interleukin-6 in the central nervous system, 10.1007/bf02740665
  52. Benveniste Etty N., Sparacio Shaun M., Gavin Norris J., Grennett Hernan E., Fuller Gerald M., Induction and regulation of interleukin-6 gene expression in rat astrocytes, 10.1016/0165-5728(90)90104-u
  53. Del Bo Roberto, Angeretti Nadia, Lucca Elisa, De Simoni Maria Grazia, Forloni Gianluigi, Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures, 10.1016/0304-3940(95)11384-9
  54. Lindberg Catharina, Selenica Maj-Linda Bardyl, Westlind-Danielsson Anita, Schultzberg Marianne, β-Amyloid Protein Structure Determines the Nature of Cytokine Release From Rat Microglia, 10.1385/jmn:27:1:001
  55. Haas Jürgen, Storch-Hagenlocher Brigitte, Biessmann Annette, Wildemann Brigitte, Inducible nitric oxide synthase and argininosuccinate synthetase: co-induction in brain tissue of patients with Alzheimer's dementia and following stimulation with β-amyloid 1–42 in vitro, 10.1016/s0304-3940(02)00095-2
  56. McAlpine Fiona E., Lee Jae-Kyung, Harms Ashley S., Ruhn Kelly A., Blurton-Jones Mathew, Hong John, Das Pritam, Golde Todd E., LaFerla Frank M., Oddo Salvatore, Blesch Armin, Tansey Malú G., Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology, 10.1016/j.nbd.2009.01.006
  57. Alkam Tursun, Nitta Atsumi, Mizoguchi Hiroyuki, Saito Kuniaki, Seshima Mitsuru, Itoh Akio, Yamada Kiyofumi, Nabeshima Toshitaka, Restraining tumor necrosis factor-alpha by thalidomide prevents the Amyloid beta-induced impairment of recognition memory in mice, 10.1016/j.bbr.2007.12.014
  58. Jiang Y., Deacon R., Anthony D.C., Campbell S.J., Inhibition of peripheral TNF can block the malaise associated with CNS inflammatory diseases, 10.1016/j.nbd.2008.06.017
  59. Morihara Takashi, Teter Bruce, Yang Fusheng, Lim Giselle P, Boudinot Sally, Boudinot F Douglas, Frautschy Sally A, Cole Greg M, Ibuprofen Suppresses Interleukin-1β Induction of Pro-Amyloidogenic α1-Antichymotrypsin to Ameliorate β-Amyloid (Aβ) Pathology in Alzheimer's Models, 10.1038/sj.npp.1300668
  60. Wang Xin, Fan Zhiqin, Wang Bingwei, Luo Jia, Ke Zun-Ji, Activation of double-stranded RNA-activated protein kinase by mild impairment of oxidative metabolism in neurons, 10.1111/j.1471-4159.2007.04978.x
  61. Shimohama Shun, 10.1023/a:1009625323388
  62. SHAKIBAEI M., JOHN T., SEIFARTH C., MOBASHERI A., Resveratrol Inhibits IL-1beta-Induced Stimulation of Caspase-3 and Cleavage of PARP in Human Articular Chondrocytes in Vitro, 10.1196/annals.1397.060
  63. Zhao Xiurong, Bausano Brian, Pike Brian R., Newcomb-Fernandez Jennifer K., Wang Kevin K.W., Shohami Esther, Ringger N.C., DeFord S.M., Anderson Douglas K., Hayes Ronald L., TNF-? stimulates caspase-3 activation and apoptotic cell death in primary septo-hippocampal cultures, 10.1002/jnr.1059
  64. Lee Jee Hoon, Park Eun Jung, Kim Ohn Soon, Kim Hee Young, Joe Eun-Hye, Jou Ilo, Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells, 10.1002/glia.20156
  65. Korotzer Andrew R., Pike Christian J., Cotman Carl W., β-Amyloid peptides induce degeneration of cultured rat microglia, 10.1016/0006-8993(93)90068-x
  66. Streit Wolfgang J., Braak Heiko, Xue Qing-Shan, Bechmann Ingo, Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease, 10.1007/s00401-009-0556-6
  67. Luo Xiao-Guang, Ding Jian-Qing, Chen Sheng-Di, Microglia in the aging brain: relevance to neurodegeneration, 10.1186/1750-1326-5-12